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Rigshospitalet - a part of Copenhagen University Hospital
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Upstaging of early colorectal cancers following improved lymph node yield after methylene blue injection

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  1. Lessons learned from histological step-sectioning of sentinel lymph nodes in penile cancer

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  2. Pitfalls of histopathological evaluation of EUS guided microbiopsies from pancreatic cystic neoplasms

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  3. Application of automated image analysis reduces the workload of manual screening of sentinel lymph node biopsies in breast cancer

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  1. Perspective: targeting VEGF-A and YKL-40 in glioblastoma - matter matters

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  2. Leukodystrophy as a feature of PIGT-CDG

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  3. First report of the neuropathological findings in a patient with leukodystrophy and compound heterozygous variants in the PIGT gene

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  4. Fatal kakeksi ved mitokondriel neurogastrointestinal encefalomyopati.

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  5. Evaluating the causality of novel sequence variants in the prion protein gene by example

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Jepsen R K, Ingeholm P & Lund E L (2012) Histopathology 61, 788-794 Upstaging of early colorectal cancers following improved lymph node yield after methylene blue injection Aims:  To evaluate whether the use of intra-arterial methylene blue injection improves lymph node yield, and to determine whether a higher lymph node count results in upstaging in colorectal cancer. Method and results:  We performed a retrospective study of colorectal cancer specimens (n = 234) 1 year after implementation of the method. All colorectal cancer specimens from the previous year served as our control group. Data concerning tumour characteristics, lymph node count, number of positive lymph nodes and success of methylene injection had been prospectively collected in accordance with the department's ongoing registration. The method was easy to implement and perform with a high rate of success (86%). The number of identified lymph nodes was highly significantly improved in the study group (P 
Original languageEnglish
JournalHistopathology
Volume61
Issue number5
Pages (from-to)788-94
Number of pages7
ISSN0309-0167
DOIs
Publication statusPublished - 2012

ID: 36514508