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Rigshospitalet - a part of Copenhagen University Hospital
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The environmental occurrence of Pseudomonas aeruginosa

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  • Stephanie Crone
  • Martha Vives-Flórez
  • Aaron M Saunders
  • Lasse Kvich
  • Matthew Malone
  • Mette H Nicolaisen
  • Esteban Martínez-García
  • Catalina Rojas-Acosta
  • Maria Catalina Gomez-Puerto
  • Henrik Calum
  • Marvin Whiteley
  • Roberto Kolter
  • Thomas Bjarnsholt
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Pseudomonas aeruginosa is generally described as ubiquitous in natural settings, such as soil and water. However, because anecdotal observations and published reports have questioned whether or not this description is true, we undertook a rigorous study using three methods to investigate the occurrence of P. aeruginosa: we investigated environmental samples, analyzed 16S rRNA data, and undertook a systematic review and meta-analysis of published data. The environmental sample screening identified P. aeruginosa as significantly associated with hydrocarbon and pesticide contaminated environments and feces, as compared to uncontaminated environments in which its prevalence was relatively low. The 16S rRNA data analysis showed that P. aeruginosa sequences were present in all habitats but were most abundant in samples from human and animals. Similarly, the meta-analysis revealed that samples obtained from environments with intense human contact had a higher prevalence of P. aeruginosa compared to those with less human contact. Thus, we found a clear tendency of P. aeruginosa to be present in places closely linked with human activity. Although P. aeruginosa may be ubiquitous in nature, it is usually scarce in pristine environments. Thus, we suggest that P. aeruginosa should be described as a bacterium largely found in locations associated with human activity.

Original languageEnglish
JournalAPMIS - Journal of Pathology, Microbiology and Immunology
Volume128
Issue number3
Pages (from-to)220-231
Number of pages12
ISSN0903-4641
DOIs
Publication statusPublished - Mar 2020

    Research areas

  • Environmental, incidence, occurrence, Pseudomonas aeruginosa, Pseudomonas Infections/microbiology, Animals, Environmental Microbiology, Humans, Pseudomonas aeruginosa/genetics, RNA, Ribosomal, 16S/genetics, Environment

ID: 58382057