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The efficacy of using computer-aided detection (CAD) for detection of breast cancer in mammography screening: a systematic review

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@article{62aac99c642c4aef8e98c5c54b6e1769,
title = "The efficacy of using computer-aided detection (CAD) for detection of breast cancer in mammography screening: a systematic review",
abstract = "Background Early detection of breast cancer (BC) is crucial in lowering the mortality. Purpose To present an overview of studies concerning computer-aided detection (CAD) in screening mammography for early detection of BC and compare diagnostic accuracy and recall rates (RR) of single reading (SR) with SR + CAD and double reading (DR) with SR + CAD. Material and Methods PRISMA guidelines were used as a review protocol. Articles on clinical trials concerning CAD for detection of BC in a screening population were included. The literature search resulted in 1522 records. A total of 1491 records were excluded by abstract and 18 were excluded by full text reading. A total of 13 articles were included. Results All but two studies from the SR vs. SR + CAD group showed an increased sensitivity and/or cancer detection rate (CDR) when adding CAD. The DR vs. SR + CAD group showed no significant differences in sensitivity and CDR. Adding CAD to SR increased the RR and decreased the specificity in all but one study. For the DR vs. SR + CAD group only one study reported a significant difference in RR. Conclusion All but two studies showed an increase in RR, sensitivity and CDR when adding CAD to SR. Compared to DR no statistically significant differences in sensitivity or CDR were reported. Additional studies based on organized population-based screening programs, with longer follow-up time, high-volume readers, and digital mammography are needed to evaluate the efficacy of CAD.",
keywords = "Computer-aided detection, breast cancer, diagnostic accuracy, early detection, mammography screening, Breast Neoplasms/diagnostic imaging, Reproducibility of Results, Breast/diagnostic imaging, Humans, Mammography/methods, Early Detection of Cancer/methods, Sensitivity and Specificity, Female, Radiographic Image Interpretation, Computer-Assisted/methods",
author = "Henriksen, {Emilie L} and Carlsen, {Jonathan F} and Vejborg, {Ilse Mm} and Nielsen, {Michael B} and Lauridsen, {Carsten A}",
year = "2019",
doi = "10.1177/0284185118770917",
language = "English",
volume = "60",
pages = "13--18",
journal = "Acta Radiologica",
issn = "0284-1851",
publisher = "Informa Healthcare",
number = "1",

}

RIS

TY - JOUR

T1 - The efficacy of using computer-aided detection (CAD) for detection of breast cancer in mammography screening

T2 - a systematic review

AU - Henriksen, Emilie L

AU - Carlsen, Jonathan F

AU - Vejborg, Ilse Mm

AU - Nielsen, Michael B

AU - Lauridsen, Carsten A

PY - 2019

Y1 - 2019

N2 - Background Early detection of breast cancer (BC) is crucial in lowering the mortality. Purpose To present an overview of studies concerning computer-aided detection (CAD) in screening mammography for early detection of BC and compare diagnostic accuracy and recall rates (RR) of single reading (SR) with SR + CAD and double reading (DR) with SR + CAD. Material and Methods PRISMA guidelines were used as a review protocol. Articles on clinical trials concerning CAD for detection of BC in a screening population were included. The literature search resulted in 1522 records. A total of 1491 records were excluded by abstract and 18 were excluded by full text reading. A total of 13 articles were included. Results All but two studies from the SR vs. SR + CAD group showed an increased sensitivity and/or cancer detection rate (CDR) when adding CAD. The DR vs. SR + CAD group showed no significant differences in sensitivity and CDR. Adding CAD to SR increased the RR and decreased the specificity in all but one study. For the DR vs. SR + CAD group only one study reported a significant difference in RR. Conclusion All but two studies showed an increase in RR, sensitivity and CDR when adding CAD to SR. Compared to DR no statistically significant differences in sensitivity or CDR were reported. Additional studies based on organized population-based screening programs, with longer follow-up time, high-volume readers, and digital mammography are needed to evaluate the efficacy of CAD.

AB - Background Early detection of breast cancer (BC) is crucial in lowering the mortality. Purpose To present an overview of studies concerning computer-aided detection (CAD) in screening mammography for early detection of BC and compare diagnostic accuracy and recall rates (RR) of single reading (SR) with SR + CAD and double reading (DR) with SR + CAD. Material and Methods PRISMA guidelines were used as a review protocol. Articles on clinical trials concerning CAD for detection of BC in a screening population were included. The literature search resulted in 1522 records. A total of 1491 records were excluded by abstract and 18 were excluded by full text reading. A total of 13 articles were included. Results All but two studies from the SR vs. SR + CAD group showed an increased sensitivity and/or cancer detection rate (CDR) when adding CAD. The DR vs. SR + CAD group showed no significant differences in sensitivity and CDR. Adding CAD to SR increased the RR and decreased the specificity in all but one study. For the DR vs. SR + CAD group only one study reported a significant difference in RR. Conclusion All but two studies showed an increase in RR, sensitivity and CDR when adding CAD to SR. Compared to DR no statistically significant differences in sensitivity or CDR were reported. Additional studies based on organized population-based screening programs, with longer follow-up time, high-volume readers, and digital mammography are needed to evaluate the efficacy of CAD.

KW - Computer-aided detection

KW - breast cancer

KW - diagnostic accuracy

KW - early detection

KW - mammography screening

KW - Breast Neoplasms/diagnostic imaging

KW - Reproducibility of Results

KW - Breast/diagnostic imaging

KW - Humans

KW - Mammography/methods

KW - Early Detection of Cancer/methods

KW - Sensitivity and Specificity

KW - Female

KW - Radiographic Image Interpretation, Computer-Assisted/methods

UR - http://www.scopus.com/inward/record.url?scp=85045851566&partnerID=8YFLogxK

U2 - 10.1177/0284185118770917

DO - 10.1177/0284185118770917

M3 - Review

VL - 60

SP - 13

EP - 18

JO - Acta Radiologica

JF - Acta Radiologica

SN - 0284-1851

IS - 1

ER -

ID: 54645650