Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Temporal changes in cause-specific death in men with localised prostate cancer treated with radical prostatectomy: a population-based, nationwide study

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Detection of Clinically Significant Prostate Cancer by Systematic TRUS-Biopsies in a Population-Based Setting Over a 20 Year Period

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Antidepressant prescriptions and associated factors in men with prostate cancer and their female partners

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Risk of Depression After Radical Prostatectomy-A Nationwide Registry-based Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Morbidity and Days Alive and Out of Hospital Within 90 Days Following Radical Cystectomy for Bladder Cancer

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

BACKGROUND AND OBJECTIVE: Changes in diagnostic work-up, histopathological assessment, and treatment of men with prostate cancer during the last 20 years have affected the prognosis. The objective was to investigate the risk of prostate cancer death in men with clinically localised prostate cancer treated with radical prostatectomy in Sweden in 2000-2010.

METHODS: Population-based, nationwide, study on men with clinically localised prostate cancer treated with radical prostatectomy in the period 2000-2010. Cox regression analyses were used to assess differences in risk of prostate cancer death according to calendar period for diagnosis and stratified on risk category.

RESULTS: The study included 19 330 men with a median follow-up of 12.4 years. Men diagnosed in 2007-2008 and 2009-2010 had a significantly lower risk of prostate cancer death compared to men diagnosed in 2000-2002. The reduced risk of prostate cancer death was restricted to men with intermediate-risk prostate cancer with no differences observed in men with low- or high-risk prostate cancer.

CONCLUSION: During the study period, the risk of prostate cancer death decreased in the total population of men with localised prostate cancer treated with radical prostatectomy. The decrease was restricted to men with intermediate-risk prostate cancer.

Original languageEnglish
JournalJournal of Surgical Oncology
Volume124
Issue number5
Pages (from-to)867-875
Number of pages9
ISSN0022-4790
DOIs
Publication statusPublished - Oct 2021

    Research areas

  • mortality, PCBaSe, prostate cancer, radical prostatectomy

ID: 67023558