Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Short-Term Flow Changes in Monochorionic Survivor Twins after Ultrasound-Guided Umbilical Cord Occlusion

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Cell-Free Fetal DNA in the Early and Late First Trimester

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Magnetic Resonance Imaging: A New Tool to Optimize the Prediction of Fetal Anemia?

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. OK-432 Treatment of Early Fetal Chylothorax: Pregnancy Outcome and Long-Term Follow-Up of 14 Cases

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Multivitamin use and risk of preeclampsia in a high-income population: A cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Alcohol intake in early pregnancy and spontaneous preterm birth: a cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Cell-Free Fetal DNA in the Early and Late First Trimester

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Physical activity during pregnancy and intelligence in sons; A cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

OBJECTIVE: To determine hemodynamic changes by Doppler ultrasound of the living fetus during 24 h after umbilical cord occlusion (UCO) in monochorionic diamniotic (MCDA) twin pregnancies.

METHOD: We conducted a prospective observational study on fetuses undergoing UCO from 2015 to 2017. Doppler parameters peak systolic velocity (PSV) and umbilical pulsatility index (PI) were obtained in the middle cerebral artery (MCA), umbilical artery (UA) and ductus venosus (DV) before and right after UCO, and at 1, 3, 6, 12, and 24 h after. We used multiple of the median (MoM) to adjust for gestational age. Spaghetti plots visualized flow changes over time. Mixed model adjusting for paired longitudinal data compared the values at different time points.

RESULTS: A total of 16 women were included. MCA-PSV dropped within the first hour after surgery from 0.91 to 0.82 MoM (p = 0.08). MCA-PI and UA-PI increased in the first hour from 0.75 to 0.91 MoM (p = 0.02) and 0.94 to 0.98 MoM (p = 0.22), respectively. The DV-PIV increased to 1.14 MoM 3 h after surgery (p = 0.07). The spaghetti plots illustrated the small changes within the first hours and showed a stabilization of flow measurements near initial values 24 h after UCO.

CONCLUSION: Within the first hours after UCO the circulation of the survivor twin undergoes small hemodynamic changes.

Original languageEnglish
JournalFetal Diagnosis and Therapy
Volume47
Issue number1
Pages (from-to)45-53
Number of pages9
ISSN1015-3837
DOIs
Publication statusPublished - 2020

ID: 58966727