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Severe acute hepatitis E infection presenting with acute abdomen and meningoencephalitis

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We present a case of a 50-year-old man admitted due to acute abdomen, icterus and fever. The patient had a history of sufficiently treated type 2 diabetes and a high daily alcohol consumption, no recent travel history and had a strictly heterosexual and monogamous way of living. A full blood count displayed severe elevated liver enzymes. A CT of the abdomen was performed and revealed steatosis but no acute abdominal pathology. During admission, the patient developed signs of meningoencephalitis. A lumbar puncture was performed, and the cerebrospinal fluid revealed lymphocytic pleocytosis consistent with mild inflammation. Furthermore, hepatitis E was found in the blood and the definitive diagnosis was established. The patient gradually recovered and was discharged within 8 days of admission. To the best of our knowledge, we present the second case describing concomitant hepatitis and meningoencephalitis, resolving spontaneously and not giving rise to sequelae.

Original languageEnglish
Article number236922
JournalBMJ Case Reports
Volume13
Issue number12
ISSN1757-790X
DOIs
Publication statusPublished - 13 Dec 2020

    Research areas

  • hepatitis and other GI infections, infectious diseases, meningitis

ID: 61560388