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Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate: occlusion in 8-year-olds according to the Modified Huddart and Bodenham index

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Scandcleft trial of primary surgery for unilateral cleft lip and palate: Craniofacial cephalometrics at 8 years

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate: dental anomalies in 8-year olds

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate: maxillary growth at eight years of age

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate. Dental arch relationships in 8 year-olds

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Association between third mandibular molar impaction and degree of root development in adolescents

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Scandcleft trial of primary surgery for unilateral cleft lip and palate: Craniofacial cephalometrics at 8 years

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate: dental anomalies in 8-year olds

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate: maxillary growth at eight years of age

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Agneta Karsten
  • Agneta Marcusson
  • Sara Rizell
  • Midia Najar Chalien
  • Arja Heliövaara
  • Annelise Küseler
  • Pål Skaare
  • Eli Brinck
  • William Shaw
  • Haydn Bellardie
  • Jeanette Mooney
  • Kirsten Mølsted
  • Paul Sæle
  • Phil Eyres
  • Gunvor Semb
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BACKGROUND: The Scandcleft international multicenter study is a prospective clinical trial of the long-term outcome after four different surgical protocols for palatal closure in patients born with unilateral cleft lip and palate (UCLP). This paper is one of a series of follow-up studies in 8-year olds.

OBJECTIVES: To evaluate the dental occlusion of 8-year-old patients after four different protocols of primary surgery for UCLP.

TRIAL DESIGN: Ten cleft centres in five countries tested three different surgical procedures for primary palatal repair in three parallel trials (Arms B, C, and D) against a common procedure (Arm A).

METHODS: Initially 448 children born with non-syndromic UCLP were included in the project. At 8 years of age, 428 children remained in the study. Dental casts of 411 patients (270 boys, 141 girls), mean age 8.1 years (range 7.0-10.0) were taken. The casts were blindly assessed with the Modified Huddart and Bodenham (MHB) index by four orthodontists. The main outcome measures were anterior (+2 to -6) and posterior (0 to -8) mean scores. Comparisons were made with previous data in 5-year-olds.

RESULTS: The inter- and intra-examiner reliability was good to excellent (0.75-0.90; 0.73-0.97), respectively. The mean total scores varied from -7.09 (Trial 2C) to -10.13 (Trial 3D). The mean anterior scores varied from -1.75 (Trial 2C) to -3.18 (Trial 1A). The mean posterior cleft-side scores varied from -4.32 (Trial 1B) to -5.21 (Trial 3D) and the mean non-cleft-side scores varied from -0.88 (Trial 2C) to -2.40 (Trial 3A). No significant differences were found within the trials. A significant difference was found between Trials 2 and 3 (Arm C/D) for the total score (P = 0.004).

CONCLUSIONS: There was no evidence of clinically significant differences in occlusion between the two surgical methods in each trial or between the trials. All mean scores showed more negative values in 8-year-olds compared with previously reported values in 5-year-olds.

TRIAL REGISTRATION: ISRCTN29932826.

Original languageEnglish
JournalAngle Orthodontist
Volume42
Issue number1
Pages (from-to)15-23
Number of pages9
ISSN0003-3219
DOIs
Publication statusPublished - Feb 2020

    Research areas

  • Child, Cleft Lip/complications, Cleft Palate/surgery, Dental Arch, Dental Models, Dental Occlusion, Female, Humans, Male, Prospective Studies, Randomized Controlled Trials as Topic, Reconstructive Surgical Procedures, Reproducibility of Results, Treatment Outcome, scandcleft
  • Health Sciences

ID: 61799214