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Rigshospitalet - a part of Copenhagen University Hospital
Published

Radiotherapy for Hodgkin Lymphoma: Reducing Toxicity While Maintaining Efficacy

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  1. Improvements in Imaging of Hodgkin Lymphoma: Positron Emission Tomography

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  2. DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?

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  3. Effects of exercise on tumor physiology and metabolism

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  1. Incidence and survival of hypopharyngeal cancer: a Danish Nation-Wide Study from 1980 to 2014

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  2. A step and shoot intensity modulated technique for total body irradiation

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Radiation therapy (RT) for Hodgkin lymphoma has changed dramatically over the past couple of decades, from the very large extended-field RT with prophylactic treatment of all the major lymph node regions to the very limited involved-site RT with treatment only of the initially macroscopically involved lymphoma volume in the combined modality setting. Technological developments in imaging, treatment planning, and treatment machines have enabled very significant reductions in radiation doses to normal organs without jeopardizing the coverage of the lymphoma. Hence, the risks of long-term adverse effects have become much smaller than those in the past. Radiation therapy for Hodgkin lymphoma is now a highly individualized treatment, tailored to each patient. The risks of this limited RT should be weighed against the risks of long-term toxicity of possible additional systemic treatment up-front and at relapse in order to select the optimal treatment combination for each individual patient.

Original languageEnglish
JournalCancer Journal
Volume24
Issue number5
Pages (from-to)237-243
Number of pages7
ISSN1528-9117
DOIs
Publication statusPublished - 25 Sep 2018

ID: 55856718