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Rigshospitalet - a part of Copenhagen University Hospital
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Prognostic scoring models in parotid gland carcinoma

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BACKGROUND: The aim was to identify prognostic factors and test three prognostic scoring models that predicted the risk of recurrence in patients with parotid gland carcinoma.

METHODS: All Danish patients with parotid gland carcinoma, treated with curative intent, from 1990 to 2015 (n = 726) were included. Potential prognostic factors were evaluated using Cox regression and competing risk analyses. The concordance of each prognostic model was estimated using Harrel's C index.

RESULTS: The study population consisted of 344 men and 382 women, with a median age of 63 years. Age above 60 years, high grade histology, T3/T4 tumor, regional lymph node metastases, and involved surgical margins were all associated with a significant reduction in recurrence-free survival. The prognostic model that agreed best with actual outcomes had a C-index of 0.76.

CONCLUSION: Prognostic scoring models may improve individualized follow-up strategies after curatively intended treatment for patients with parotid gland carcinoma.

Original languageEnglish
JournalHead and Neck
Volume43
Issue number7
Pages (from-to)2081-2090
Number of pages10
ISSN1043-3074
DOIs
Publication statusPublished - Jul 2021

    Research areas

  • follow-up, parotid gland carcinoma, prognosis, prognostic scoring model, recurrence risk

ID: 64640044