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Post procedure headache in patients treated for neurovascular arteriovenous malformations and aneurysms using endovascular therapy

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@article{4c776a6aa48147ebb87ed75d548b6766,
title = "Post procedure headache in patients treated for neurovascular arteriovenous malformations and aneurysms using endovascular therapy",
abstract = "BACKGROUND: Though endovascular therapy (EVT) is increasingly applied in the treatment of intracranial vascular lesions, little is known about the effect of EVT on post-procedure headache. We aimed to investigate the prevalence of headache in patients who have undergone EVT for cerebral arteriovenous malformations (AVMs) and aneurysms.METHODS: A total of 324 patients underwent EVT treatment for aneurysms and AVMs at the Danish National Hospital from January 2012 to December 2014. We applied strict exclusion criteria in order to minimize the effect of other factors on headache occurrence, e.g., craniotomy. Eligible subjects were phone-interviewed using a purpose-developed semi-structured questionnaire. Headaches were classified according to ICHD-III beta criteria.RESULTS: The 59 patients underwent treatment of aneurysms (n = 43), cranial dural fistulas (n = 11), and AVMs (n = 5). There was a significant increase in overall headache (p = 0.017) and tension-type headache (TTH) (p = 0.012) within the first 3 months after EVT compared to 1 month before EVT. However, at interview time (median 2.5 years post-EVT), the increase in overall headache, migraine, and tension-type headache was not statistically significant. A minority of patients experienced headaches for the first time within 3 months of their EVT (migraine 4, TTH 10). At interview time, 50 % of these new headaches still persisted.CONCLUSION: Our results suggest a temporary increase in headache in the first 3 months after EVT, which normalizes over time. Clinicians may use this knowledge to better inform their patients of functional outcomes after their EVT procedure.",
keywords = "Adult, Aged, Cerebral Angiography, Endovascular Procedures, Female, Headache, Humans, Intracranial Aneurysm, Intracranial Arteriovenous Malformations, Male, Middle Aged, Neurosurgical Procedures, Postoperative Complications, Prevalence, Surveys and Questionnaires, Treatment Outcome, Journal Article",
author = "Sabrina Khan and Amin, {Faisal Mohammad} and John Hauerberg and Markus Holtmannsp{\"o}tter and Petersen, {Julie Falkenberg} and Zainab Fakhril-Din and David Gaist and Messoud Ashina",
year = "2016",
month = dec,
doi = "10.1186/s10194-016-0666-1",
language = "English",
volume = "17",
pages = "73",
journal = "Journal of Headache and Pain",
issn = "1129-2369",
publisher = "Springer Italia Srl",
number = "1",

}

RIS

TY - JOUR

T1 - Post procedure headache in patients treated for neurovascular arteriovenous malformations and aneurysms using endovascular therapy

AU - Khan, Sabrina

AU - Amin, Faisal Mohammad

AU - Hauerberg, John

AU - Holtmannspötter, Markus

AU - Petersen, Julie Falkenberg

AU - Fakhril-Din, Zainab

AU - Gaist, David

AU - Ashina, Messoud

PY - 2016/12

Y1 - 2016/12

N2 - BACKGROUND: Though endovascular therapy (EVT) is increasingly applied in the treatment of intracranial vascular lesions, little is known about the effect of EVT on post-procedure headache. We aimed to investigate the prevalence of headache in patients who have undergone EVT for cerebral arteriovenous malformations (AVMs) and aneurysms.METHODS: A total of 324 patients underwent EVT treatment for aneurysms and AVMs at the Danish National Hospital from January 2012 to December 2014. We applied strict exclusion criteria in order to minimize the effect of other factors on headache occurrence, e.g., craniotomy. Eligible subjects were phone-interviewed using a purpose-developed semi-structured questionnaire. Headaches were classified according to ICHD-III beta criteria.RESULTS: The 59 patients underwent treatment of aneurysms (n = 43), cranial dural fistulas (n = 11), and AVMs (n = 5). There was a significant increase in overall headache (p = 0.017) and tension-type headache (TTH) (p = 0.012) within the first 3 months after EVT compared to 1 month before EVT. However, at interview time (median 2.5 years post-EVT), the increase in overall headache, migraine, and tension-type headache was not statistically significant. A minority of patients experienced headaches for the first time within 3 months of their EVT (migraine 4, TTH 10). At interview time, 50 % of these new headaches still persisted.CONCLUSION: Our results suggest a temporary increase in headache in the first 3 months after EVT, which normalizes over time. Clinicians may use this knowledge to better inform their patients of functional outcomes after their EVT procedure.

AB - BACKGROUND: Though endovascular therapy (EVT) is increasingly applied in the treatment of intracranial vascular lesions, little is known about the effect of EVT on post-procedure headache. We aimed to investigate the prevalence of headache in patients who have undergone EVT for cerebral arteriovenous malformations (AVMs) and aneurysms.METHODS: A total of 324 patients underwent EVT treatment for aneurysms and AVMs at the Danish National Hospital from January 2012 to December 2014. We applied strict exclusion criteria in order to minimize the effect of other factors on headache occurrence, e.g., craniotomy. Eligible subjects were phone-interviewed using a purpose-developed semi-structured questionnaire. Headaches were classified according to ICHD-III beta criteria.RESULTS: The 59 patients underwent treatment of aneurysms (n = 43), cranial dural fistulas (n = 11), and AVMs (n = 5). There was a significant increase in overall headache (p = 0.017) and tension-type headache (TTH) (p = 0.012) within the first 3 months after EVT compared to 1 month before EVT. However, at interview time (median 2.5 years post-EVT), the increase in overall headache, migraine, and tension-type headache was not statistically significant. A minority of patients experienced headaches for the first time within 3 months of their EVT (migraine 4, TTH 10). At interview time, 50 % of these new headaches still persisted.CONCLUSION: Our results suggest a temporary increase in headache in the first 3 months after EVT, which normalizes over time. Clinicians may use this knowledge to better inform their patients of functional outcomes after their EVT procedure.

KW - Adult

KW - Aged

KW - Cerebral Angiography

KW - Endovascular Procedures

KW - Female

KW - Headache

KW - Humans

KW - Intracranial Aneurysm

KW - Intracranial Arteriovenous Malformations

KW - Male

KW - Middle Aged

KW - Neurosurgical Procedures

KW - Postoperative Complications

KW - Prevalence

KW - Surveys and Questionnaires

KW - Treatment Outcome

KW - Journal Article

U2 - 10.1186/s10194-016-0666-1

DO - 10.1186/s10194-016-0666-1

M3 - Journal article

C2 - 27550214

VL - 17

SP - 73

JO - Journal of Headache and Pain

JF - Journal of Headache and Pain

SN - 1129-2369

IS - 1

ER -

ID: 49611741