Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Physical activity in myotonic dystrophy type 1

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Characteristic muscle signatures assessed by quantitative MRI in patients with Bethlem myopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. European muscle MRI study in limb girdle muscular dystrophy type R1/2A (LGMDR1/LGMD2A)

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Efficacy and Safety of Rozanolixizumab in Moderate to Severe Generalized Myasthenia Gravis: A Phase 2 Randomized Control Trial

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Episodic hyperCKaemia may be a feature of α-methylacyl-coenzyme A racemase deficiency

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Data from the European registry for patients with McArdle disease and other muscle glycogenoses (EUROMAC)

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Creation and implementation of a European registry for patients with McArdle disease and other muscle glycogenoses (EUROMAC registry)

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

BACKGROUND: Physical inactivity is associated with lifestyle diseases and exercise of moderate intensity seems beneficial in DM1, but knowledge about physical activity and predictors of physical activity in individuals with myotonic dystrophy type 1 (DM1) is limited. The objective of this study is to assess physical activity and predictors of physical activity in individuals with DM1.

METHODS: Sixty-seven adults with DM1 and 39 healthy adults were recruited. Physical activity was monitored by accelerometry and assessed using the International Physical Activity Questionnaire. Age, marital status, education, apathy, cognition, fatigue, and muscle strength were assessed as predictors of physical activity in DM1.

RESULTS: The individuals with DM1 were on average - 187 min (p < 0.00001) objectively and - 48% (p = 0.001) subjectively less physically active per week compared to healthy controls. Education was the only predictor of physical activity in DM1 (p = 0.02).

CONCLUSIONS: Individuals with DM1 are less physically active compared to healthy controls and only half of the patients fulfilled minimum requirements for recommended physical activity. Education is the only predictor of physical activity in DM1. Thus, enhancement of physical activity in individuals with DM1 might be suggested, and especially in the less educated individuals, but RCT studies are needed to guide exact recommendations.

Original languageEnglish
JournalJournal of Neurology
Volume267
Issue number6
Pages (from-to)1679-1686
Number of pages8
ISSN0340-5354
DOIs
Publication statusPublished - Jun 2020

ID: 61074950