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Rigshospitalet - a part of Copenhagen University Hospital
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PET imaging in patients with brain metastasis-report of the RANO/PET group

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  1. The natural history of Vestibular Schwannoma growth - prospective 40-year data from an unselected national cohort

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  3. Sex-specific gene and pathway modeling of inherited glioma risk

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  1. Prevalence of cognitive impairment and its relation to mental health in Danish lymphoma survivors

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  2. Somatostatin receptor-targeted radiopeptide therapy in treatment-refractory meningioma: Individual Patient Data Meta-analysis

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  3. Comparison of the clinical impact of 2-[18F]FDG-PET and cerebrospinal fluid biomarkers in patients suspected of Alzheimer's disease

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  4. Hybrid 2-[18F] FDG PET/MRI in premanifest Huntington's disease gene-expansion carriers: The significance of partial volume correction

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  • Norbert Galldiks
  • Karl-Josef Langen
  • Nathalie L Albert
  • Marc Chamberlain
  • Riccardo Soffietti
  • Michelle M Kim
  • Ian Law
  • Emilie Le Rhun
  • Susan Chang
  • Julian Schwarting
  • Stephanie E Combs
  • Matthias Preusser
  • Peter Forsyth
  • Whitney Pope
  • Michael Weller
  • Jörg C Tonn
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Brain metastases (BM) from extracranial cancer are associated with significant morbidity and mortality. Effective local treatment options are stereotactic radiotherapy, including radiosurgery or fractionated external beam radiotherapy, and surgical resection. The use of systemic treatment for intracranial disease control also is improving. BM diagnosis, treatment planning, and follow-up is most often based on contrast-enhanced magnetic resonance imaging (MRI). However, anatomic imaging modalities including standard MRI have limitations in accurately characterizing posttherapeutic reactive changes and treatment response. Molecular imaging techniques such as positron emission tomography (PET) characterize specific metabolic and cellular features of metastases, potentially providing clinically relevant information supplementing anatomic MRI. Here, the Response Assessment in Neuro-Oncology working group provides recommendations for the use of PET imaging in the clinical management of patients with BM based on evidence from studies validated by histology and/or clinical outcome.

Original languageEnglish
JournalNeuro-Oncology
Volume21
Issue number5
Pages (from-to)585-595
Number of pages11
ISSN1522-8517
DOIs
Publication statusPublished - 6 May 2019

ID: 59320346