Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Multirater Validation of Peripapillary Hyperreflective Ovoid Mass-like Structures (PHOMS)

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Identical Horner Syndrome in Homozygotic Twins Caused by Non-Traumatic Internal Carotid Artery Dissection

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Optic Nerve Head Blood Flow Analysis in Patients with Optic Disc Drusen Using Laser Speckle Flowgraphy

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. An Estimation of the Risk of Pseudotumor Cerebri among Users of the Levonorgestrel Intrauterine Device

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Ipsilateral Recurrence of Optic Disc Drusen-Associated Anterior Ischemic Optic Neuropathy in a 15-Year-Old Boy

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Optic disc drusen diagnosed by optical coherence tomography in a 3-year-old child

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Fibrinogen: A potential biomarker for predicting disease severity in multiple sclerosis

    Research output: Contribution to journalReviewpeer-review

  • Axel Petzold
  • Valerie Biousse
  • Lulu Bursztyn
  • Fiona Costello
  • Alison Crum
  • Kathleen Digre
  • Clare Fraser
  • J Alex Fraser
  • Bradley Katz
  • Neringa Jurkute
  • Nancy Newman
  • Jette Lautrup-Battistini
  • Mitchell Lawlor
  • Petra Liskova
  • Birgit Lorenz
  • Lasse Malmqvist
  • Jason Peragallo
  • Patrick Sibony
  • Prem Subramanian
  • Robert Rejdak
  • Katarzyna Nowomiejska
  • Valerie Touitou
  • Judith Warner
  • Marianne Wegener
  • Sui Wong
  • Patrick Yu-Wai-Man
  • Steffen Hamann
View graph of relations

Peripapillary hyperreflective ovoid mass-like structures (PHOMS) are a new retinal optical coherence tomography (OCT) finding. The Optic Disc Drusen Studies Consortium had made recommendations to distinguish PHOMS from true optic disc drusen (ODD) in 2018. While publications on PHOMS have increased since then, the accuracy of the definition of PHOMS and reliability of detection is unknown. In this multi-rater study, we demonstrate that the 2018 definition of PHOMS resulted in a poor multi-rater kappa of 0.356. We performed a Delphi consensus process to develop a consistent and refined definition of PHOMS with clear principles around the nature of PHOMS and how they differ from normal anatomy. Fifty explanatory teaching slides, provided as supplementary material, allowed our expert group of raters to achieve a good level of agreement (kappa 0.701, 50 OCT scans, 21 raters). We recommend adopting the refined definition for PHOMS.

Original languageEnglish
JournalNeuro-Ophthalmology
Volume44
Issue number6
Pages (from-to)413-414
Number of pages2
ISSN0165-8107
DOIs
Publication statusPublished - 2020

ID: 61975398