Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Morphological evidence of biofilm in chronic obstructive sialadenitis

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{a07e0dc2453640e9832531ea4cbe6190,
title = "Morphological evidence of biofilm in chronic obstructive sialadenitis",
abstract = "OBJECTIVE: Bacterial infection is a common finding in acute sialadenitis and may play a role in the chronicity of the condition. This study investigated if bacterial biofilm is present in submandibular chronic obstructive sialadenitis.METHODS: A descriptive case-control study was conducted that compared 10 histological sections of submandibular glands with chronic obstructive sialadenitis, to 10 histological sections of the healthy part of submandibular glands with pleomorphic adenoma. Fluorescence in situ hybridisation and confocal laser scanning microscopy visualised evidence of bacterial biofilm.RESULTS: In the chronic obstructive sialadenitis group, 5 out of 10 histological sections showed morphological evidence of bacterial biofilm. In the control group, there was no sign of bacterial biofilm formation.CONCLUSION: Morphological evidence of bacterial biofilm was found in the submandibular gland sections from patients with chronic sialadenitis and suggests a role in the chronicity of submandibular chronic obstructive sialadenitis.",
author = "Schr{\o}der, {S A} and S Eickhardt and T Bjarnsholt and T N{\o}rgaard and P Hom{\o}e",
year = "2018",
doi = "10.1017/S0022215118000646",
language = "English",
volume = "132",
pages = "611--614",
journal = "Mediterranean Journal of Otology",
issn = "0022-2151",
publisher = "Cambridge University Press",
number = "7",

}

RIS

TY - JOUR

T1 - Morphological evidence of biofilm in chronic obstructive sialadenitis

AU - Schrøder, S A

AU - Eickhardt, S

AU - Bjarnsholt, T

AU - Nørgaard, T

AU - Homøe, P

PY - 2018

Y1 - 2018

N2 - OBJECTIVE: Bacterial infection is a common finding in acute sialadenitis and may play a role in the chronicity of the condition. This study investigated if bacterial biofilm is present in submandibular chronic obstructive sialadenitis.METHODS: A descriptive case-control study was conducted that compared 10 histological sections of submandibular glands with chronic obstructive sialadenitis, to 10 histological sections of the healthy part of submandibular glands with pleomorphic adenoma. Fluorescence in situ hybridisation and confocal laser scanning microscopy visualised evidence of bacterial biofilm.RESULTS: In the chronic obstructive sialadenitis group, 5 out of 10 histological sections showed morphological evidence of bacterial biofilm. In the control group, there was no sign of bacterial biofilm formation.CONCLUSION: Morphological evidence of bacterial biofilm was found in the submandibular gland sections from patients with chronic sialadenitis and suggests a role in the chronicity of submandibular chronic obstructive sialadenitis.

AB - OBJECTIVE: Bacterial infection is a common finding in acute sialadenitis and may play a role in the chronicity of the condition. This study investigated if bacterial biofilm is present in submandibular chronic obstructive sialadenitis.METHODS: A descriptive case-control study was conducted that compared 10 histological sections of submandibular glands with chronic obstructive sialadenitis, to 10 histological sections of the healthy part of submandibular glands with pleomorphic adenoma. Fluorescence in situ hybridisation and confocal laser scanning microscopy visualised evidence of bacterial biofilm.RESULTS: In the chronic obstructive sialadenitis group, 5 out of 10 histological sections showed morphological evidence of bacterial biofilm. In the control group, there was no sign of bacterial biofilm formation.CONCLUSION: Morphological evidence of bacterial biofilm was found in the submandibular gland sections from patients with chronic sialadenitis and suggests a role in the chronicity of submandibular chronic obstructive sialadenitis.

U2 - 10.1017/S0022215118000646

DO - 10.1017/S0022215118000646

M3 - Journal article

VL - 132

SP - 611

EP - 614

JO - Mediterranean Journal of Otology

JF - Mediterranean Journal of Otology

SN - 0022-2151

IS - 7

ER -

ID: 54759654