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Rigshospitalet - a part of Copenhagen University Hospital
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Menstrual disturbances and fertility in chronic alcoholic women

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  1. Effect of alcohol and glucose infusion on pituitary-gonadal hormones in normal females

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  • U Becker
  • H Tønnesen
  • N Kaas-Claesson
  • C Gluud
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Data on menstrual pattern, gynecological disorders and infertility were obtained from 51 chronic alcoholic women aged 20--42 years attending an outpatient clinic for alcoholics, using 51 randomly drawn age-matched healthy women as controls. A higher variability (P less than 0.05) in the duration of both menstrual cycle and menstrual flow was recorded in the chronic alcoholic women during active alcoholism. A higher frequency (P less than 0.05) of menstrual disturbances (70% vs. 55%) and uterine curettages (38% vs. 16%) were found in the alcoholic women. The latter reported more abortions (63% vs. 28%, P less than 0.001) and miscarriages (23% vs. 8%, P less than 0.05) than controls, but due to a higher number of pregnancies in the alcoholic group the proportion of abortions and miscarriages did not differ significantly. No differences existed between the groups regarding frequency of difficult conception. Social classification had no independent influence on the results. The study shows that chronic alcoholic women are more prone to menstrual abnormalities and are at greater risk of gynecological interventions, while they do not seem to have reduced fertility.
Original languageEnglish
JournalDrug and Alcohol Dependence
Volume24
Issue number1
Pages (from-to)75-82
Number of pages8
ISSN0376-8716
Publication statusPublished - Aug 1989

    Research areas

  • Adolescent, Adult, Alcoholism, Female, Fertility, Humans, Menstruation, Menstruation Disturbances

ID: 38932357