Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Low morbidity in Danish patients with common variable immunodeficiency disorder infected with severe acute respiratory syndrome coronavirus 2

Research output: Contribution to journalJournal articleResearchpeer-review

  1. The increasing importance of Haemophilus influenzae in community-acquired pneumonia: results from a Danish cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Hospitalizations for infections by age and sex: register-based study of Danish children 1977-2014

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. External validation of the HANDOC score - high sensitivity to identify patients with non-beta-haemolytic streptococcal endocarditis

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Limited anti-HIV neutralizing antibody breadth and potency before and after HIV superinfection in Danish men who have sex with men

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. The experience of pregnancy among women living with HIV in Nordic countries: A qualitative narrative enquiry

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Intensive Care Antifungal Stewardship Programme Based on T2Candida PCR and Candida Mannan Antigen: A Prospective Study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Surgical management of rhinocerebral mucormycosis: A case series

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Symptomatisk SARS-CoV-2-reinfektion hos ellers rask person

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

BACKGROUND: Manifestations and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are not well documented in patients with common variable immunodeficiency disorder (CVID).

METHODS: A Danish nationwide retrospective clinician-reported survey.

RESULTS: Eleven patients with CVID and SARS-CoV-2 infection were identified. The median age was 50 years (range 22-72). All were on immunoglobulin replacement therapy. Eight patients had other pre-existing co-morbidities. Three patients were asymptomatic during the SARS-CoV-2 infection while seven developed mild coronavirus disease 2019 (COVID-19). One patient had more severe disease with hypoxia and required oxygen therapy. This patient had multiple co-morbidities including well known risk factors for severe COVID-19. All patients recovered.

CONCLUSIONS: The results suggest that CVID may not be a risk factor for severe COVID-19. However, further monitoring of this immunodeficient population is needed to confirm our observation.

Original languageEnglish
Article number1957144
JournalInfectious diseases (London, England)
Volume53
Issue number12
Pages (from-to)953-958
Number of pages6
ISSN2374-4235
DOIs
Publication statusPublished - 11 Aug 2021

    Research areas

  • common variable immunodeficiency, COVID-19, inborn errors of immunity, primary immunodeficiency, SARS-CoV-2

ID: 67245518