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Rigshospitalet - a part of Copenhagen University Hospital

Long-term outcomes after out-of-hospital cardiac arrest in relation to socioeconomic status

Research output: Contribution to journalJournal articleResearchpeer-review

  • Sidsel Møller
  • Mads Wissenberg
  • Kathrine Søndergaard
  • Kristian Kragholm
  • Fredrik Folke
  • Carolina Malta Hansen
  • Kristian B Ringgren
  • Julie Andersen
  • Freddy Lippert
  • Amalie Lykkemark Møller
  • Lars Køber
  • Thomas Alexander Gerds
  • Christian Torp-Pedersen
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AIMS: This study aimed to examine whether socioeconomic differences exist in long-term outcomes after out-of-hospital cardiac arrest (OHCA).

METHODS: We included 2,309 30-day OHCA survivors ≥30 years of age from the Danish Cardiac Arrest Registry, 2001-2014, divided in tertiles of household income (low, medium, high). Absolute probabilities were estimated using logistic regression for 1-year outcomes and cause-specific Cox regression for 5-year outcomes. Differences between income-groups were standardized with respect to age, sex, education and comorbidities.

RESULTS: High-income compared to low-income patients had highest 1-year (96.4% vs. 84.2%) and 5-year (87.6% vs. 64.1%) survival, and lowest 1-year (11.3% vs. 7.4%) and 5-year (13.7% vs. 8.6%) risk of anoxic brain damage/nursing home admission. The corresponding standardized probability differences were 8.2% (95%CI 4.7-11.6%) and 13.9% (95%CI 8.2-19.7%) for 1- and 5-year survival, respectively; and -4.5% (95%CI -8.2 to -1.2%) and -5.1% (95%CI -9.3 to -0.9%) for 1- and 5-year risk of anoxic brain damage/nursing home admission, respectively. Among 831 patients <66 years working prior to OHCA, 72.1% returned to work within 1 year and 80.8% within 5 years. High-income compared to low-income patients had the highest chance of 1-year (76.4% vs. 58.8%) and 5-year (85.3% vs. 70.6%) return to work with the corresponding absolute probability difference of 18.0% (95%CI 3.8-32.7%) for 1-year and 9.4% (95%CI -3.4-22.3%) for 5-year.

CONCLUSION: Patients of high socioeconomic status had higher probability of long-term survival and return to work, and lower risk of anoxic brain damage/nursing home admission after OHCA compared to patients of low socioeconomic status.

Original languageEnglish
Pages (from-to)336-344
Number of pages9
Publication statusPublished - Oct 2021

    Research areas

  • Long-term outcomes, Nursing home, OHCA, Return to work, Socioeconomic factors, Survival

ID: 67035504