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Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort

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Harvard

Andersen, ZJ, Cramer, J, Jørgensen, JT, Dehlendorff, C, Amini, H, Mehta, A, Cole-Hunter, T, Mortensen, LH, Westendorp, R, So, R, Li, S, Hoffmann, B, Loft, S, Bräuner, EV, Ketzel, M, Hertel, O, Brandt, J, Jensen, SS, Christensen, JH, Geels, C, Frohn, LM, Backalarz, C, Simonsen, MK & Lim, Y-H 2021, 'Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort', Environmental Health Perspectives, vol. 129, no. 8, 087002, pp. 87002. https://doi.org/10.1289/EHP8090

APA

Andersen, Z. J., Cramer, J., Jørgensen, J. T., Dehlendorff, C., Amini, H., Mehta, A., Cole-Hunter, T., Mortensen, L. H., Westendorp, R., So, R., Li, S., Hoffmann, B., Loft, S., Bräuner, E. V., Ketzel, M., Hertel, O., Brandt, J., Jensen, S. S., Christensen, J. H., ... Lim, Y-H. (2021). Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort. Environmental Health Perspectives, 129(8), 87002. [087002]. https://doi.org/10.1289/EHP8090

CBE

Andersen ZJ, Cramer J, Jørgensen JT, Dehlendorff C, Amini H, Mehta A, Cole-Hunter T, Mortensen LH, Westendorp R, So R, Li S, Hoffmann B, Loft S, Bräuner EV, Ketzel M, Hertel O, Brandt J, Jensen SS, Christensen JH, Geels C, Frohn LM, Backalarz C, Simonsen MK, Lim Y-H. 2021. Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort. Environmental Health Perspectives. 129(8):87002. https://doi.org/10.1289/EHP8090

MLA

Vancouver

Author

Andersen, Zorana J ; Cramer, Johannah ; Jørgensen, Jeanette T ; Dehlendorff, Christian ; Amini, Heresh ; Mehta, Amar ; Cole-Hunter, Tom ; Mortensen, Laust H ; Westendorp, Rudi ; So, Rina ; Li, Shuo ; Hoffmann, Barbara ; Loft, Steffen ; Bräuner, Elvira V ; Ketzel, Matthias ; Hertel, Ole ; Brandt, Jørgen ; Jensen, Steen Solvang ; Christensen, Jesper H ; Geels, Camilla ; Frohn, Lise M ; Backalarz, Claus ; Simonsen, Mette K ; Lim, Youn-Hee. / Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort. In: Environmental Health Perspectives. 2021 ; Vol. 129, No. 8. pp. 87002.

Bibtex

@article{2fb30af6fce54503adbb49bc1b9dd6c8,
title = "Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort",
abstract = "BACKGROUND: Associations between long-term exposure to air pollution and road traffic noise have been established for ischemic heart disease, but findings have been mixed for atrial fibrillation (AF).OBJECTIVES: The goal of the study was to examine associations of long-term exposure to road traffic noise and air pollution with AF.METHODS: Time-varying Cox regression models were used to estimate associations of 1-, 3-, and 23-y mean road traffic noise and air pollution exposures with AF incidence in 23,528 women enrolled in the Danish Nurse Cohort (age >44y at baseline in 1993 or 1999). AF diagnoses were ascertained via the Danish National Patient Register. Annual mean weighted 24-h average road traffic noise levels (Lden) at the nurses' residences, since 1970, were estimated using the Nord2000 model, and annual mean levels of particulate matter with a diameter <2.5μm (PM2.5) and nitrogen dioxide (NO2) were estimated using the DEHM/UBM/AirGIS model.RESULTS: Of 23,528 nurses with no prior AF diagnosis at the cohort baseline, 1,522 developed AF during follow-up. In a fully adjusted model (including PM2.5), the estimated risk of AF was 18% higher [hazard ratio (HR); 95% confidence interval (CI): 1.18; 1.02, 1.36] in nurses with residential 3-y mean Lden levels >58 dB vs. <48 dB, with similar findings for 1-y mean exposures. A 3.9-μg/m3 increase in 3-y mean PM2.5 was associated with incident AF before and after adjustment for concurrent exposure to road traffic noise (HR 1.09; 95% CI: 1.00, 1.20 and 1.08; 95% CI: 0.97, 1.19, respectively). Associations with 1-y mean PM2.5 exposures were positive but closer to the null and not significant. Associations with NO2 were null for all time periods before and after adjustment for road traffic noise and inverse when adjusted for concurrent PM2.5.CONCLUSION: Our analysis of prospective data from a cohort of Danish female nurses followed for up to 14 y provided suggestive evidence of independent associations between incident AF and 1- and 3-y exposures to road traffic noise and PM2.5. https://doi.org/10.1289/EHP8090.",
author = "Andersen, {Zorana J} and Johannah Cramer and J{\o}rgensen, {Jeanette T} and Christian Dehlendorff and Heresh Amini and Amar Mehta and Tom Cole-Hunter and Mortensen, {Laust H} and Rudi Westendorp and Rina So and Shuo Li and Barbara Hoffmann and Steffen Loft and Br{\"a}uner, {Elvira V} and Matthias Ketzel and Ole Hertel and J{\o}rgen Brandt and Jensen, {Steen Solvang} and Christensen, {Jesper H} and Camilla Geels and Frohn, {Lise M} and Claus Backalarz and Simonsen, {Mette K} and Youn-Hee Lim",
year = "2021",
month = aug,
doi = "10.1289/EHP8090",
language = "English",
volume = "129",
pages = "87002",
journal = "Environmental Health Perspectives",
issn = "0091-6765",
publisher = "U.S. Department of Health and Human Services National Institute of Environmental Health Sciences",
number = "8",

}

RIS

TY - JOUR

T1 - Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort

AU - Andersen, Zorana J

AU - Cramer, Johannah

AU - Jørgensen, Jeanette T

AU - Dehlendorff, Christian

AU - Amini, Heresh

AU - Mehta, Amar

AU - Cole-Hunter, Tom

AU - Mortensen, Laust H

AU - Westendorp, Rudi

AU - So, Rina

AU - Li, Shuo

AU - Hoffmann, Barbara

AU - Loft, Steffen

AU - Bräuner, Elvira V

AU - Ketzel, Matthias

AU - Hertel, Ole

AU - Brandt, Jørgen

AU - Jensen, Steen Solvang

AU - Christensen, Jesper H

AU - Geels, Camilla

AU - Frohn, Lise M

AU - Backalarz, Claus

AU - Simonsen, Mette K

AU - Lim, Youn-Hee

PY - 2021/8

Y1 - 2021/8

N2 - BACKGROUND: Associations between long-term exposure to air pollution and road traffic noise have been established for ischemic heart disease, but findings have been mixed for atrial fibrillation (AF).OBJECTIVES: The goal of the study was to examine associations of long-term exposure to road traffic noise and air pollution with AF.METHODS: Time-varying Cox regression models were used to estimate associations of 1-, 3-, and 23-y mean road traffic noise and air pollution exposures with AF incidence in 23,528 women enrolled in the Danish Nurse Cohort (age >44y at baseline in 1993 or 1999). AF diagnoses were ascertained via the Danish National Patient Register. Annual mean weighted 24-h average road traffic noise levels (Lden) at the nurses' residences, since 1970, were estimated using the Nord2000 model, and annual mean levels of particulate matter with a diameter <2.5μm (PM2.5) and nitrogen dioxide (NO2) were estimated using the DEHM/UBM/AirGIS model.RESULTS: Of 23,528 nurses with no prior AF diagnosis at the cohort baseline, 1,522 developed AF during follow-up. In a fully adjusted model (including PM2.5), the estimated risk of AF was 18% higher [hazard ratio (HR); 95% confidence interval (CI): 1.18; 1.02, 1.36] in nurses with residential 3-y mean Lden levels >58 dB vs. <48 dB, with similar findings for 1-y mean exposures. A 3.9-μg/m3 increase in 3-y mean PM2.5 was associated with incident AF before and after adjustment for concurrent exposure to road traffic noise (HR 1.09; 95% CI: 1.00, 1.20 and 1.08; 95% CI: 0.97, 1.19, respectively). Associations with 1-y mean PM2.5 exposures were positive but closer to the null and not significant. Associations with NO2 were null for all time periods before and after adjustment for road traffic noise and inverse when adjusted for concurrent PM2.5.CONCLUSION: Our analysis of prospective data from a cohort of Danish female nurses followed for up to 14 y provided suggestive evidence of independent associations between incident AF and 1- and 3-y exposures to road traffic noise and PM2.5. https://doi.org/10.1289/EHP8090.

AB - BACKGROUND: Associations between long-term exposure to air pollution and road traffic noise have been established for ischemic heart disease, but findings have been mixed for atrial fibrillation (AF).OBJECTIVES: The goal of the study was to examine associations of long-term exposure to road traffic noise and air pollution with AF.METHODS: Time-varying Cox regression models were used to estimate associations of 1-, 3-, and 23-y mean road traffic noise and air pollution exposures with AF incidence in 23,528 women enrolled in the Danish Nurse Cohort (age >44y at baseline in 1993 or 1999). AF diagnoses were ascertained via the Danish National Patient Register. Annual mean weighted 24-h average road traffic noise levels (Lden) at the nurses' residences, since 1970, were estimated using the Nord2000 model, and annual mean levels of particulate matter with a diameter <2.5μm (PM2.5) and nitrogen dioxide (NO2) were estimated using the DEHM/UBM/AirGIS model.RESULTS: Of 23,528 nurses with no prior AF diagnosis at the cohort baseline, 1,522 developed AF during follow-up. In a fully adjusted model (including PM2.5), the estimated risk of AF was 18% higher [hazard ratio (HR); 95% confidence interval (CI): 1.18; 1.02, 1.36] in nurses with residential 3-y mean Lden levels >58 dB vs. <48 dB, with similar findings for 1-y mean exposures. A 3.9-μg/m3 increase in 3-y mean PM2.5 was associated with incident AF before and after adjustment for concurrent exposure to road traffic noise (HR 1.09; 95% CI: 1.00, 1.20 and 1.08; 95% CI: 0.97, 1.19, respectively). Associations with 1-y mean PM2.5 exposures were positive but closer to the null and not significant. Associations with NO2 were null for all time periods before and after adjustment for road traffic noise and inverse when adjusted for concurrent PM2.5.CONCLUSION: Our analysis of prospective data from a cohort of Danish female nurses followed for up to 14 y provided suggestive evidence of independent associations between incident AF and 1- and 3-y exposures to road traffic noise and PM2.5. https://doi.org/10.1289/EHP8090.

UR - http://www.scopus.com/inward/record.url?scp=85112680308&partnerID=8YFLogxK

U2 - 10.1289/EHP8090

DO - 10.1289/EHP8090

M3 - Journal article

C2 - 34338552

VL - 129

SP - 87002

JO - Environmental Health Perspectives

JF - Environmental Health Perspectives

SN - 0091-6765

IS - 8

M1 - 087002

ER -

ID: 66962092