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Rigshospitalet - a part of Copenhagen University Hospital
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Individualised therapy is more cost-effective than dose intensification in patients with Crohn's disease who lose response to anti-TNF treatment: a randomised, controlled trial

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  4. Long-term follow-up of patients on home parenteral nutrition in Europe: implications for intestinal transplantation

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  2. Lewis and AB0 blood group-phenotypes in periodontitis, cardiovascular disease, obesity and stroke

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  3. Gasotransmitters and the immune system: Mode of action and novel therapeutic targets

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  4. Biological anti-TNF drugs: immunogenicity underlying treatment failure and adverse events

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  • Casper Steenholdt
  • Jørn Brynskov
  • Ole Østergaard Thomsen
  • Lars Kristian Munck
  • Jan Fallingborg
  • Lisbet Ambrosius Christensen
  • Gitte Pedersen
  • Jens Christian William Kjeldsen
  • Bent Ascanius Jacobsen
  • Anne Sophie Oxholm
  • Jakob Kjellberg
  • Klaus Bendtzen
  • Mark Andrew Ainsworth
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Although the reasons for secondary loss of response to infliximab (IFX) maintenance therapy in Crohn's disease vary, dose intensification is usually recommended. This study investigated the cost-effectiveness of interventions defined by an algorithm designed to identify specific reasons for therapeutic failure.
Original languageEnglish
JournalGut
Volume4
Issue number63
Pages (from-to)919
Number of pages9
ISSN0017-5749
DOIs
Publication statusPublished - 2014

ID: 42508094