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Increased Y-chromosome detection by SRY duplexing

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@article{d8fa03f209e043a4a87dd0948479314e,
title = "Increased Y-chromosome detection by SRY duplexing",
abstract = "Determining fetal sex noninvasively is dependent of a robust assay. We designed a novel SRY assay and combined it with a SRY assay from literature forming a duplex assay with the same fluorescent dye to increase detection of Y-chromosome at low cell-free fetal DNA or chimeric DNA concentrations.",
keywords = "Chromosomes, Human, Y, DNA, Denmark, Female, Fluorescent Dyes, Genes, sry, Gestational Age, Humans, Male, Nucleic Acid Probes, Predictive Value of Tests, Pregnancy, Prenatal Diagnosis, Real-Time Polymerase Chain Reaction, Sensitivity and Specificity, Sex Determination Analysis",
author = "Hansen, {Morten H{\o}gh} and Clausen, {Frederik Banch} and Dziegiel, {Morten Hanefeld}",
note = "Copyright {\circledC} 2012 S. Karger AG, Basel.",
year = "2012",
doi = "10.1159/000335350",
language = "English",
volume = "31",
pages = "185--90",
journal = "Fetal Diagnosis and Therapy",
issn = "1015-3837",
publisher = "S./Karger AG",
number = "3",

}

RIS

TY - JOUR

T1 - Increased Y-chromosome detection by SRY duplexing

AU - Hansen, Morten Høgh

AU - Clausen, Frederik Banch

AU - Dziegiel, Morten Hanefeld

N1 - Copyright © 2012 S. Karger AG, Basel.

PY - 2012

Y1 - 2012

N2 - Determining fetal sex noninvasively is dependent of a robust assay. We designed a novel SRY assay and combined it with a SRY assay from literature forming a duplex assay with the same fluorescent dye to increase detection of Y-chromosome at low cell-free fetal DNA or chimeric DNA concentrations.

AB - Determining fetal sex noninvasively is dependent of a robust assay. We designed a novel SRY assay and combined it with a SRY assay from literature forming a duplex assay with the same fluorescent dye to increase detection of Y-chromosome at low cell-free fetal DNA or chimeric DNA concentrations.

KW - Chromosomes, Human, Y

KW - DNA

KW - Denmark

KW - Female

KW - Fluorescent Dyes

KW - Genes, sry

KW - Gestational Age

KW - Humans

KW - Male

KW - Nucleic Acid Probes

KW - Predictive Value of Tests

KW - Pregnancy

KW - Prenatal Diagnosis

KW - Real-Time Polymerase Chain Reaction

KW - Sensitivity and Specificity

KW - Sex Determination Analysis

U2 - 10.1159/000335350

DO - 10.1159/000335350

M3 - Journal article

VL - 31

SP - 185

EP - 190

JO - Fetal Diagnosis and Therapy

JF - Fetal Diagnosis and Therapy

SN - 1015-3837

IS - 3

ER -

ID: 36330394