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Rigshospitalet - a part of Copenhagen University Hospital
Published

Increased Y-chromosome detection by SRY duplexing

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Cell-Free Fetal DNA in the Early and Late First Trimester

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Short-Term Flow Changes in Monochorionic Survivor Twins after Ultrasound-Guided Umbilical Cord Occlusion

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Magnetic Resonance Imaging: A New Tool to Optimize the Prediction of Fetal Anemia?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Next Generation Sequencing-Based Fetal ABO Blood Group Prediction by Analysis of Cell-Free DNA from Maternal Plasma

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Targeted Rhesus immunoglobulin for RhD negative women undergoing an induced abortion: a clinical pilot study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Blood group genotyping of blood donors: validation of a highly accurate routine method

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Noninvasive fetal RHD genotyping to guide targeted anti-D prophylaxis-an external quality assessment workshop

    Research output: Contribution to journalJournal articleResearchpeer-review

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Determining fetal sex noninvasively is dependent of a robust assay. We designed a novel SRY assay and combined it with a SRY assay from literature forming a duplex assay with the same fluorescent dye to increase detection of Y-chromosome at low cell-free fetal DNA or chimeric DNA concentrations.
Original languageEnglish
JournalFetal Diagnosis and Therapy
Volume31
Issue number3
Pages (from-to)185-90
Number of pages6
ISSN1015-3837
DOIs
Publication statusPublished - 2012

    Research areas

  • Chromosomes, Human, Y, DNA, Denmark, Female, Fluorescent Dyes, Genes, sry, Gestational Age, Humans, Male, Nucleic Acid Probes, Predictive Value of Tests, Pregnancy, Prenatal Diagnosis, Real-Time Polymerase Chain Reaction, Sensitivity and Specificity, Sex Determination Analysis

ID: 36330394