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Ictal source imaging and electroclinical correlation in self-limited epilepsy with centrotemporal spikes

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@article{a81eb530a48942e9bf3f30976d51c34a,
title = "Ictal source imaging and electroclinical correlation in self-limited epilepsy with centrotemporal spikes",
abstract = "PURPOSE: To elucidate the localization of ictal EEG activity, and correlate it to semiological features in self-limited epilepsy with centrotemporal spikes (formerly called {"}benign epilepsy with centrotemporal spikes{"}).METHODS: We have performed ictal electric source imaging, and we analysed electroclinical correlations in three patients with self-limited epilepsy with centrotemporal spikes.RESULTS: The source of the evolving rhythmic ictal activity (9.7-13.5Hz) localized to the operculo-insular area. The rhythmic EEG activity was time-locked to the contralateral focal motor seizure manifestation: facial rhythmic myoclonic jerks, with the same frequency as the analysed ictal rhythm. In all three patients, the seizures had fluctuating course with pauses of clinical and electrographic seizure activity, ranging from 0.4 to 7s.CONCLUSION: Source imaging of ictal EEG activity in patients with self-limited epilepsy with centrotemporal spikes showed activation of the operculo-insular area, time-locked to the contralateral focal myoclonic jerks. Fragmented seizure dynamics, with fluctuating course, previously described as a hallmark in patients with psychogenic non-epileptic seizures, can occur in rolandic seizures.",
keywords = "Journal Article",
author = "J{\o}rgen Alving and Fabricius, {Martin Ejler} and Ivana Rosenzweig and S{\'a}ndor Beniczky",
note = "Copyright {\circledC} 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.",
year = "2017",
doi = "10.1016/j.seizure.2017.09.006",
language = "English",
volume = "52",
pages = "7--10",
journal = "Seizure : the journal of the British Epilepsy Association",
issn = "1059-1311",
publisher = "W.B./Saunders Co. Ltd",

}

RIS

TY - JOUR

T1 - Ictal source imaging and electroclinical correlation in self-limited epilepsy with centrotemporal spikes

AU - Alving, Jørgen

AU - Fabricius, Martin Ejler

AU - Rosenzweig, Ivana

AU - Beniczky, Sándor

N1 - Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

PY - 2017

Y1 - 2017

N2 - PURPOSE: To elucidate the localization of ictal EEG activity, and correlate it to semiological features in self-limited epilepsy with centrotemporal spikes (formerly called "benign epilepsy with centrotemporal spikes").METHODS: We have performed ictal electric source imaging, and we analysed electroclinical correlations in three patients with self-limited epilepsy with centrotemporal spikes.RESULTS: The source of the evolving rhythmic ictal activity (9.7-13.5Hz) localized to the operculo-insular area. The rhythmic EEG activity was time-locked to the contralateral focal motor seizure manifestation: facial rhythmic myoclonic jerks, with the same frequency as the analysed ictal rhythm. In all three patients, the seizures had fluctuating course with pauses of clinical and electrographic seizure activity, ranging from 0.4 to 7s.CONCLUSION: Source imaging of ictal EEG activity in patients with self-limited epilepsy with centrotemporal spikes showed activation of the operculo-insular area, time-locked to the contralateral focal myoclonic jerks. Fragmented seizure dynamics, with fluctuating course, previously described as a hallmark in patients with psychogenic non-epileptic seizures, can occur in rolandic seizures.

AB - PURPOSE: To elucidate the localization of ictal EEG activity, and correlate it to semiological features in self-limited epilepsy with centrotemporal spikes (formerly called "benign epilepsy with centrotemporal spikes").METHODS: We have performed ictal electric source imaging, and we analysed electroclinical correlations in three patients with self-limited epilepsy with centrotemporal spikes.RESULTS: The source of the evolving rhythmic ictal activity (9.7-13.5Hz) localized to the operculo-insular area. The rhythmic EEG activity was time-locked to the contralateral focal motor seizure manifestation: facial rhythmic myoclonic jerks, with the same frequency as the analysed ictal rhythm. In all three patients, the seizures had fluctuating course with pauses of clinical and electrographic seizure activity, ranging from 0.4 to 7s.CONCLUSION: Source imaging of ictal EEG activity in patients with self-limited epilepsy with centrotemporal spikes showed activation of the operculo-insular area, time-locked to the contralateral focal myoclonic jerks. Fragmented seizure dynamics, with fluctuating course, previously described as a hallmark in patients with psychogenic non-epileptic seizures, can occur in rolandic seizures.

KW - Journal Article

U2 - 10.1016/j.seizure.2017.09.006

DO - 10.1016/j.seizure.2017.09.006

M3 - Journal article

VL - 52

SP - 7

EP - 10

JO - Seizure : the journal of the British Epilepsy Association

JF - Seizure : the journal of the British Epilepsy Association

SN - 1059-1311

ER -

ID: 52625610