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Rigshospitalet - a part of Copenhagen University Hospital
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Historical epidemiology of hepatitis C virus (HCV) in selected countries

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Low compliance with hepatocellular carcinoma screening guidelines in hepatitis B/C virus co-infected HIV patients with cirrhosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Hepatocellular carcinoma in patients with chronic hepatitis C and cirrhosis in Denmark: a nationwide cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Strategies to manage hepatitis C virus (HCV) disease burden

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  4. The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Predictors of antiviral treatment initiation in hepatitis C virus-infected patients: a Danish cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  • P Bruggmann
  • T Berg
  • A L H Øvrehus
  • C Moreno
  • C E Brandão Mello
  • F Roudot-Thoraval
  • R T Marinho
  • M Sherman
  • S D Ryder
  • J Sperl
  • U Akarca
  • I Balık
  • F Bihl
  • M Bilodeau
  • A J Blasco
  • M Buti
  • F Calinas
  • J L Calleja
  • H Cheinquer
  • P B Christensen
  • M Clausen
  • H S M Coelho
  • M Cornberg
  • M E Cramp
  • G J Dore
  • W Doss
  • A S Duberg
  • M H El-Sayed
  • G Ergör
  • G Esmat
  • C Estes
  • K Falconer
  • J Félix
  • M L G Ferraz
  • P R Ferreira
  • S Frankova
  • J García-Samaniego
  • J Gerstoft
  • J A Giria
  • F L Gonçales
  • E Gower
  • M Gschwantler
  • M Guimarães Pessôa
  • C Hézode
  • H Hofer
  • P Husa
  • R Idilman
  • M Kåberg
  • K D E Kaita
  • A Kautz
  • S Kaymakoglu
  • M Krajden
  • H Krarup
  • W Laleman
  • D Lavanchy
  • P Lázaro
  • P Marotta
  • S Mauss
  • M C Mendes Correa
  • B Müllhaupt
  • R P Myers
  • Francesco Negro
  • V Nemecek
  • N Örmeci
  • J Parkes
  • K M Peltekian
  • A Ramji
  • H Razavi
  • N Reis
  • S K Roberts
  • W M Rosenberg
  • R Sarmento-Castro
  • C Sarrazin
  • D Semela
  • G E Shiha
  • W Sievert
  • P Stärkel
  • R E Stauber
  • A J Thompson
  • P Urbanek
  • I van Thiel
  • H Van Vlierberghe
  • D Vandijck
  • W Vogel
  • I Waked
  • H Wedemeyer
  • N Weis
  • J Wiegand
  • A Yosry
  • A Zekry
  • P Van Damme
  • S Aleman
  • S J Hindman
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Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

Original languageEnglish
JournalJournal of Viral Hepatitis
Volume21 Suppl 1
Pages (from-to)5-33
Number of pages29
ISSN1352-0504
DOIs
Publication statusPublished - May 2014

    Research areas

  • Antiviral Agents, Global Health, Hepatitis C, Chronic, Humans, Incidence, Liver Transplantation, Prevalence, Survival Analysis

ID: 45003867