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Rigshospitalet - a part of Copenhagen University Hospital
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FSHB-211 and FSHR 2039 are associated with serum levels of follicle-stimulating hormone and antimüllerian hormone in healthy girls: a longitudinal cohort study

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  1. Shortcomings of an unphysiological triggering of oocyte maturation using human chorionic gonadotropin

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  2. Semen quality among young healthy men taking protein supplements

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  3. Ninth-grade school achievement in Danish children conceived following fertility treatment: a population-based cohort study

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  4. Psychological stress, stressful life events, male factor infertility, and testicular function: a cross-sectional study

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  1. DIAGNOSIS OF ENDOCRINE DISEASE: Sex steroid action in adolescence: too much, too little; too early, too late

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  2. Trend of Menarcheal Age among Korean Girls

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  3. Age-related changes in human Leydig cell status

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To investigate whether genetic polymorphisms in the FSH pathway (FSHB-211 G→T and FSHR 2039 A→G) affect serum levels of FSH, antimüllerian hormone (AMH), and age at pubertal onset. FSH secretion and FSH signal transduction are enhanced in carriers of FSHB GG and FSHR AA, respectively. Furthermore, the combined genotype FSHB GG+FSHR AA is the most favorable for male gonadal function, but the effect of this genotype has never been evaluated in peripubertal females. AMH is a marker of ovarian function and is negatively correlated with FSH in prepubertal girls.
Original languageEnglish
JournalFertility and Sterility
Volume100
Issue number4
Pages (from-to)1089-1095
ISSN0015-0282
DOIs
Publication statusPublished - 11 Jul 2013

ID: 39023528