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Rigshospitalet - a part of Copenhagen University Hospital
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From mother to child: investigation of prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring

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  1. Enantiomeric ratios as an indicator of exposure processes for persistent pollutants in human placentas

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Endocrine Disrupting Chemicals and Risk of Testicular Cancer: A Systematic Review and Meta-analysis

    Research output: Contribution to journalReviewResearchpeer-review

  2. Brain tumours in children and adolescents may affect the circadian rhythm and quality of life

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  3. Brain tumours result in sleep disorders in children and adolescents

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  4. Paracetamol use during pregnancy - a call for precautionary action

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The exposure levels of placenta and paired breast milk samples to selected organochlorine compounds and pesticides from Danish and Finnish samples have been investigated. p,p'-DDE is the dominant pollutant, beta-HCH, hexachlorobenzene, endosulfan-I, dieldrin, oxychlordane, cis-heptachlor epoxide and p,p'-DDT being the other major constituents. Their concentrations are linearly correlated between milk and placenta in similar patterns for Danish and Finnish samples. Milk samples have higher levels of these pollutants than placenta on lipid base. However, the apparently not correlated compounds, such as alpha-HCH, pentachlorobenzene, pentachloroanisole and methoxychlor, are generally accumulated more in placenta, which may suggest a tissue specific metabolic activity. Thus, depending on the compound of interest, biomonitoring may be done in placenta only or in both matrices.

Original languageEnglish
JournalChemosphere
Volume67
Issue number9
Pages (from-to)S256-62
ISSN0045-6535
DOIs
Publication statusPublished - Apr 2007

    Research areas

  • Adult, Denmark, Dichlorodiphenyl Dichloroethylene, Environmental Monitoring, Environmental Pollutants, Female, Finland, Humans, Hydrocarbons, Chlorinated, Infant, Newborn, Insecticides, Male, Milk, Human, Mothers, Pesticides, Placenta, Pregnancy, Prenatal Exposure Delayed Effects

ID: 44943775