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Rigshospitalet - a part of Copenhagen University Hospital
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Familial Hemiplegic Migraine and Recurrent Episodes of Psychosis: A Case Report

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Familial hemiplegic migraine (FHM) is a rare autosomal dominant form of migraine with motor aura. We present a case report of a father and son with very similar attacks of hemiplegic migraine and recurrent episodes of accompanying psychoses. Previously, such episodes led to hospitalization and extended clinical examinations, which further worsened the psychoses. Since the episodes were recognized as related to the hemiplegic migraine, a treatment strategy combining sleep and sedation was initiated and progression onto psychosis was almost completely avoided in both father and son. Genetic analyses found no causal gene mutation in the three known FHM genes, suggesting that the phenotype is caused by a yet unidentified mutation.

Original languageEnglish
Article number55
JournalHeadache Online
Volume55
Issue number7
Pages (from-to)1004-1007
Number of pages4
ISSN1526-4610
DOIs
Publication statusPublished - 18 Jun 2015

ID: 45445133