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Factors Associated With and Outcomes After Ventricular Fibrillation Before and During Primary Angioplasty in Patients With ST-Segment Elevation Myocardial Infarction

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  1. Causes of Mortality in the Marfan Syndrome(from a Nationwide Register Study)

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  2. Usefulness of Transcatheter Aortic Valve Implantation for Treatment of Pure Native Aortic Valve Regurgitation

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  1. Prevalence and risk factors of prolonged QT interval and electrocardiographic abnormalities in persons living with HIV

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  2. Association between Type D personality and outcomes in patients with non-ischemic heart failure

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  3. Prevalence of infective endocarditis in patients with positive blood cultures: a Danish nationwide study

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We aimed to assess the risk factors and outcome of ventricular fibrillation (VF) before and during primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction. From 1999 to 2012, we consecutively enrolled 5,373 patients with ST-segment elevation myocardial infarction. In total, 410 of the patients had VF before and 88 had VF during PPCI. During a mean follow-up of 4.2 years, 1,196 subjects died. A logistic regression model identified younger age, anterior infarct, Killip class >I at admission, and a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I to be significantly associated with VF before PPCI, whereas inferior infarct, a preprocedural Thrombolysis In Myocardial Infarction flow grade of 0 to I, and Killip class >I at admission were significantly associated with VF during PPCI. All-cause mortality was evaluated using the Cox regression model. Compared with the patients without VF, those with VF before or during PPCI had a significantly increased 30-day mortality, with an adjusted hazard ratio = 3.40 (95% confidence interval 1.70 to 6.70) and 4.20 (95% confidence interval 1.30 to 13.30), respectively. Importantly, there was no tendency of 30-day mortality difference between VF before and during PPCI (p = 0.170). In patients with VF before or during PPCI who survived for at least 30 days, there was no increase in the long-term mortality. In conclusion, our data suggest that 30-day mortality is the same for patients with VF before PPCI compared with VF during PPCI, and the occurrence of VF before or during PPCI was associated with increased 30-day mortality but not with long-term mortality.

Original languageEnglish
JournalThe American journal of cardiology
Volume116
Issue number5
Pages (from-to)678-85
Number of pages8
ISSN0002-9149
DOIs
Publication statusPublished - 1 Sep 2015

    Research areas

  • Aged, Angioplasty, Balloon, Coronary, Cause of Death, Denmark, Electrocardiography, Female, Follow-Up Studies, Humans, Intraoperative Period, Male, Middle Aged, Myocardial Infarction, Preoperative Period, Prognosis, Retrospective Studies, Survival Rate, Time Factors, Treatment Outcome, Ventricular Fibrillation

ID: 46173921