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Extensive extraintestinal manifestations of ulcerative colitis in a patient initially suspected to have disseminated malignancy

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A 44-year-old patient with known ulcerative colitis presented with abdominal pain and an abdominal mass. CT revealed cecal stranding, a mass at the left colonic flexure involving the pancreas and multiple lesions in the lungs, retroperitoneum and liver. The patient had also developed a scalp rash as well as impaired hearing. Biopsies from the abdominal mass and lungs revealed necrotic inflammation, and the clinical suspicion of malignancy could not be ruled out. After further examination, the patient was treated with high-dose steroids, which rapidly reduced the extraintestinal manifestations. Due to a persistent abscess formation at the left colonic flexure and pancreas, the patient was referred to our hospital for a total colectomy. Histology showed acute and chronic inflammation with cryptitis, indicating ulcerative colitis. Our case is a rare presentation of extensive extraintestinal disease in organs such as the lungs and liver, as well as necrotic mass formation at the colon site which mimicked malignancy.

Original languageEnglish
Article numbere241163
JournalBMJ Case Reports
Volume14
Issue number11
ISSN1757-790X
DOIs
Publication statusPublished - 19 Nov 2021

Bibliographical note

© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.

    Research areas

  • Adult, Colectomy, Colitis, Ulcerative/complications, Humans, Neoplasms

ID: 70611251