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Rigshospitalet - a part of Copenhagen University Hospital
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Effect of enamel matrix derivative and parathyroid hormone on bone formation in standardized osseous defects: an experimental study in minipigs

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  2. The sandwich osteotomy technique to treat vertical alveolar bone defects prior to implant placement: a systematic review

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  3. Timing af implantatindsættelse efter traumebetinget tandtab

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  4. Implant Therapy in the Esthetic Zone

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  5. Strategies for Treatment of Tooth Loss after Trauma to the Anterior Region of Young Patients

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

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Previous experimental studies have indicated that locally administered enamel matrix derivative (EMD) and parathyroid hormone (PTH) may have a stimulatory effect on bone formation. However, it is not clear if the positive effect of EMD is related to its effect on the periodontium as a whole or directly on the bone-forming cells. In addition, it is not known if the presentation of PTH by adding the amino acid sequence Arg-Gly-Asp (RGD) is essential for its osteopromotive effect. Local delivery of a bioactive substance at the right time and in the right concentration often constitutes a major challenge. Polyethylene glycol-based hydrogel (PEG) is a degradable vehicle developed for delivery of bioactive proteins. To enhance the mechanical stability of the PEG-bioactive substance complex, an osteoconductive bone substitute material is often needed.
Original languageEnglish
JournalJournal of Periodontology
Volume82
Issue number8
Pages (from-to)1197-205
Number of pages9
ISSN0022-3492
DOIs
Publication statusPublished - 1 Aug 2011

ID: 32801221