Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

DIAGNOSIS OF ENDOCRINE DISEASE: Sex steroid action in adolescence: too much, too little; too early, too late

Research output: Contribution to journalReviewpeer-review

DOI

  1. The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Distinguishing between hidden testes and anorchia: The role of endocrine evaluation in infancy and childhood

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Heritability of pubertal timing: detailed evaluation of specific milestones in healthy boys and girls

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Abstract: This review aims to cover the subject of sex steroid action in adolescence. It will include situations with too little sex steroid action, as seen in for example, Turners syndrome and androgen insensitivity issues, too much sex steroid action as seen in adolescent PCOS, CAH and gynecomastia, too late sex steroid action as seen in constitutional delay of growth and puberty and too early sex steroid action as seen in precocious puberty. This review will cover the etiology, the signs and symptoms which the clinician should be attentive to, important differential diagnoses to know and be able to distinguish, long-term health and social consequences of these hormonal disorders and the course of action with regards to medical treatment in the pediatric endocrinological department and for the general practitioner. This review also covers situations with exogenous sex steroid application for therapeutic purposes in the adolescent and young adult. This includes gender-affirming therapy in the transgender child and hormone treatment of tall statured children. It gives some background information of the cause of treatment, the patient's motivation for medicating (or self-medicating), long-term consequences of exogenous sex steroid treatment and clinical outcome of this treatment.

Original languageEnglish
JournalEuropean Journal of Endocrinology
Volume184
Issue number1
Pages (from-to)R17-R28
ISSN0804-4643
DOIs
Publication statusPublished - Jan 2021

    Research areas

  • Adolescent, Adolescent Health, Endocrine System Diseases/drug therapy, Female, Gonadal Steroid Hormones/metabolism, Humans, Male, Puberty/metabolism, Puberty, Precocious/drug therapy, Young Adult

ID: 61413166