Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Detection of atrial fibrillation with implantable loop recorders in horses
AU - Buhl, Rikke
AU - Hesselkilde, Eva M
AU - Carstensen, Helena
AU - Fenner, Merle F
AU - Jespersen, Thomas
AU - Tfelt-Hansen, Jacob
AU - Michael Sattler, Stefan
N1 - © 2020 The Authors. Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.
PY - 2021/3
Y1 - 2021/3
N2 - BACKGROUND: Cardiac arrhythmias in horses are diagnosed by auscultation or electrocardiogram (ECG), which results in a low sensitivity for detecting arrhythmias that occur sporadically. Implantable loop recorders (ILRs) are small ECG devices placed subcutaneously, to automatically detect arrhythmias in human patients.OBJECTIVES: To test ILRs ability to detect atrial fibrillation (AF) in horses. Furthermore, we hypothesised that anatomical location of the implant site might influence signal quality. Signal quality was evaluated both during exercise and over time.STUDY DESIGN: Experimental study.METHODS: In five Standardbred mares, eleven ILRs were implanted subcutaneously in up to three different positions (Front: pectoral region, Left-6: sixth left intercostal space and Ventral: xiphoid region) and AF induced. The R- and T-wave amplitudes were measured in all positions over time during AF. AF burden automatically registered by the ILRs over a 2-month period was compared with selected Holter ECG recordings.RESULTS: All three positions had stable R- and T-wave amplitudes during the study period and were of sufficient quality to allow AF detection at rest. The position Left-6 showed significantly higher R- and T-wave amplitudes compared with the other positions. During submaximal exercise only the Left-6 position was able to record ECG signals of diagnostic quality. No position yielded diagnostic signals at maximum exercise due to artefacts.MAIN LIMITATIONS: Few horses and ILRs included and no spontaneous AF episodes were studied.CONCLUSIONS: This preliminary study indicates that ILRs can be used for AF detection in horses, but the anatomical location is important for optimal ECG quality. Despite insufficient quality during exercise, ILRs were suitable for AF detection at rest. Therefore, the ILR may be a valuable diagnostic tool for detecting paroxysmal AF in horses.
AB - BACKGROUND: Cardiac arrhythmias in horses are diagnosed by auscultation or electrocardiogram (ECG), which results in a low sensitivity for detecting arrhythmias that occur sporadically. Implantable loop recorders (ILRs) are small ECG devices placed subcutaneously, to automatically detect arrhythmias in human patients.OBJECTIVES: To test ILRs ability to detect atrial fibrillation (AF) in horses. Furthermore, we hypothesised that anatomical location of the implant site might influence signal quality. Signal quality was evaluated both during exercise and over time.STUDY DESIGN: Experimental study.METHODS: In five Standardbred mares, eleven ILRs were implanted subcutaneously in up to three different positions (Front: pectoral region, Left-6: sixth left intercostal space and Ventral: xiphoid region) and AF induced. The R- and T-wave amplitudes were measured in all positions over time during AF. AF burden automatically registered by the ILRs over a 2-month period was compared with selected Holter ECG recordings.RESULTS: All three positions had stable R- and T-wave amplitudes during the study period and were of sufficient quality to allow AF detection at rest. The position Left-6 showed significantly higher R- and T-wave amplitudes compared with the other positions. During submaximal exercise only the Left-6 position was able to record ECG signals of diagnostic quality. No position yielded diagnostic signals at maximum exercise due to artefacts.MAIN LIMITATIONS: Few horses and ILRs included and no spontaneous AF episodes were studied.CONCLUSIONS: This preliminary study indicates that ILRs can be used for AF detection in horses, but the anatomical location is important for optimal ECG quality. Despite insufficient quality during exercise, ILRs were suitable for AF detection at rest. Therefore, the ILR may be a valuable diagnostic tool for detecting paroxysmal AF in horses.
KW - Animals
KW - Atrial Fibrillation/diagnosis
KW - Electrocardiography, Ambulatory/veterinary
KW - Electrocardiography/veterinary
KW - Female
KW - Horse Diseases/diagnosis
KW - Horses
KW - Humans
KW - Prostheses and Implants/veterinary
KW - cardiac arrhythmia
KW - cardiology
KW - horse
KW - atrial fibrillation
KW - implantable loop recorder
UR - http://www.scopus.com/inward/record.url?scp=85087204668&partnerID=8YFLogxK
U2 - 10.1111/evj.13301
DO - 10.1111/evj.13301
M3 - Journal article
C2 - 32506470
VL - 53
SP - 397
EP - 403
JO - Equine veterinary journal. Supplement
JF - Equine veterinary journal. Supplement
SN - 2042-3306
IS - 2
ER -
ID: 62373475