Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Childhood asthma and physical activity: a systematic review with meta-analysis and Graphic Appraisal Tool for Epidemiology assessment

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Antibiotic prescribing in paediatric inpatients in Ghana: a multi-centre point prevalence survey

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Maternal thyroid disorder in pregnancy and risk of cerebral palsy in the child: a population-based cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Leisure time physical activity in 9- to 11-year-old children born moderately preterm: a cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Social, dietary and clinical correlates of oedema in children with severe acute malnutrition: a cross-sectional study

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. A randomized controlled trial on a multicomponent intervention for overweight school-aged children - Copenhagen, Denmark

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. SPEF2- And HYDIN-mutant cilia lack the central pair-associated protein SPEF2, aiding primary ciliary dyskinesia diagnostics

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. The Controversies and Difficulties of Diagnosing Primary Ciliary Dyskinesia

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The impact of mannose-binding lectin polymorphisms on lung function in primary ciliary dyskinesia

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Long-Term Lung Function and Exercise Capacity in Postinfectious chILD

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Lene Lochte
  • Kim G Nielsen
  • Poul Erik Petersen
  • Thomas A E Platts-Mills
View graph of relations

BACKGROUND: Childhood asthma is a global problem affecting the respiratory health of children. Physical activity (PA) plays a role in the relationship between asthma and respiratory health. We hypothesized that a low level of PA would be associated with asthma in children and adolescents. The objectives of our study were to (1) summarize the evidence available on associations between PA and asthma prevalence in children and adolescents and (2) assess the role of PA in new-onset or incident asthma among children and adolescents.

METHODS: We searched Medline, the Cochrane Library, and Embase and extracted data from original articles that met the inclusion criteria. Summary odds ratios (ORs) and confidence intervals (CIs) were used to express the results of the meta-analysis (forest plot). We explored heterogeneity using funnel plots and the Graphic Appraisal Tool for Epidemiology (GATE).

RESULTS: We retrieved 1,571 titles and selected 11 articles describing three cohort and eight cross-sectional studies for inclusion. A meta-analysis of the cohort studies revealed a risk of new-onset asthma in children with low PA (OR [95 % CI] 1.32 [0.95; 1.84] [random effects] and 1.35 [1.13; 1.62] [fixed effects]). Three cross-sectional studies identified significant positive associations between childhood asthma or asthma symptoms and low PA.

CONCLUSIONS: Children and adolescents with low PA levels had an increased risk of new-onset asthma, and some had a higher risk of current asthma/or wheezing; however, there was some heterogeneity among the studies. This review reveals a critical need for future longitudinal assessments of low PA, its mechanisms, and its implications for incident asthma in children. The systematic review was prospectively registered at PROSPERO (registration number: CRD42014013761; available at: http://www.crd.york.ac.uk/PROSPERO [accessed: 24 March 2016]).

Original languageEnglish
JournalBMC Pediatrics
Volume16
Pages (from-to)50
ISSN1471-2431
DOIs
Publication statusPublished - 18 Apr 2016

    Research areas

  • Adolescent, Asthma, Child, Child, Preschool, Global Health, Humans, Incidence, Infant, Infant, Newborn, Models, Statistical, Motor Activity, Prevalence, Protective Factors, Risk Factors, Journal Article, Meta-Analysis, Review

ID: 49874074