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Rigshospitalet - a part of Copenhagen University Hospital
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Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK

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  • Maria Sode Rønne
  • Malene Heidemann
  • Louise Lylloff
  • Anders J Schou
  • Jakob Tarp
  • Jens Ole Laursen
  • Niklas Rye Jørgensen
  • Steffen Husby
  • Niels Wedderkopp
  • Christian Mølgaard
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This longitudinal study examined associations of bone mass with physical activity and vitamin D level over more than 6 years through puberty. A total of 663 participants (320 boys) with mean age 9.6 years at baseline (10-17 years at follow-up), underwent dual energy X-ray absorptiometry, anthropometry and blood samples for vitamin D at least twice during the study period (with three possible time-points). Physical activity was assessed using accelerometers at follow-up. A positive association was found between percent time spent at vigorous physical activity and total-body less head bone mineral content (β = 5.8, p = 0.002). The magnitude of this association increased with maturational development; thus physical activity may have a greater influence on bone mass in the more mature participants. The vitamin D levels were also positively associated with bone mass. A high degree of tracking was observed with changes in anthropometric Z scores predictive of deviation from tracking. No environmental factor predicted deviation from tracking.

Original languageEnglish
JournalCalcified Tissue International
Volume104
Issue number1
Pages (from-to)1-13
Number of pages13
ISSN0171-967X
DOIs
Publication statusPublished - Jan 2019

ID: 58197186