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Audiovestibular Loss of Function Correlates in Vestibular Schwannomas

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@article{677ba7b17ed54023a2b11ad623491672,
title = "Audiovestibular Loss of Function Correlates in Vestibular Schwannomas",
abstract = "OBJECTIVES: The aim of the present study was to investigate the relationships between tumor size, hearing, and vestibular outcomes in patients with vestibular schwannomas (VSs).MATERIALS AND METHODS: Adult patients (n=124) with unilateral extrameatal VS prior to surgery were included in the study. This was a retrospective cohort study of preoperative audiovestibular investigations including audiometry, discrimination test, caloric test, cervical vestibular evoked myogenic potential (c-VEMP), and ocular vestibular evoked myogenic potential (o-VEMP).RESULTS: The difference between lesioned and non-lesioned ear was significant for all audiovestibular outcomes. The mean caloric deficit was 74{\%}. No tumor sided o-VEMPs were elicited. Caloric deficit correlated with hearing loss measured with pure tone average and discrimination score. c-VEMP deficit was significantly associated with severe hearing loss and larger tumors.CONCLUSION: The presence of VS leads to a significant deterioration of audiovestibular function in all objective measures. Caloric test and o-VEMPS are sensitive though unspecific measures of VSs. Increasing tumor size is not directly associated with hearing loss and only somewhat to vestibular deficit. However, audiovestibular findings are correlated.",
author = "Niels West and M{\o}ller, {Martin Nue} and S{\o}ren Hansen and Per Cay{\'e}-Thomasen",
year = "2018",
month = "8",
doi = "10.5152/iao.2018.5500",
language = "English",
volume = "14",
pages = "161--165",
journal = "Mediterranean Journal of Otology",
issn = "0022-2151",
publisher = "Cambridge University Press",
number = "2",

}

RIS

TY - JOUR

T1 - Audiovestibular Loss of Function Correlates in Vestibular Schwannomas

AU - West, Niels

AU - Møller, Martin Nue

AU - Hansen, Søren

AU - Cayé-Thomasen, Per

PY - 2018/8

Y1 - 2018/8

N2 - OBJECTIVES: The aim of the present study was to investigate the relationships between tumor size, hearing, and vestibular outcomes in patients with vestibular schwannomas (VSs).MATERIALS AND METHODS: Adult patients (n=124) with unilateral extrameatal VS prior to surgery were included in the study. This was a retrospective cohort study of preoperative audiovestibular investigations including audiometry, discrimination test, caloric test, cervical vestibular evoked myogenic potential (c-VEMP), and ocular vestibular evoked myogenic potential (o-VEMP).RESULTS: The difference between lesioned and non-lesioned ear was significant for all audiovestibular outcomes. The mean caloric deficit was 74%. No tumor sided o-VEMPs were elicited. Caloric deficit correlated with hearing loss measured with pure tone average and discrimination score. c-VEMP deficit was significantly associated with severe hearing loss and larger tumors.CONCLUSION: The presence of VS leads to a significant deterioration of audiovestibular function in all objective measures. Caloric test and o-VEMPS are sensitive though unspecific measures of VSs. Increasing tumor size is not directly associated with hearing loss and only somewhat to vestibular deficit. However, audiovestibular findings are correlated.

AB - OBJECTIVES: The aim of the present study was to investigate the relationships between tumor size, hearing, and vestibular outcomes in patients with vestibular schwannomas (VSs).MATERIALS AND METHODS: Adult patients (n=124) with unilateral extrameatal VS prior to surgery were included in the study. This was a retrospective cohort study of preoperative audiovestibular investigations including audiometry, discrimination test, caloric test, cervical vestibular evoked myogenic potential (c-VEMP), and ocular vestibular evoked myogenic potential (o-VEMP).RESULTS: The difference between lesioned and non-lesioned ear was significant for all audiovestibular outcomes. The mean caloric deficit was 74%. No tumor sided o-VEMPs were elicited. Caloric deficit correlated with hearing loss measured with pure tone average and discrimination score. c-VEMP deficit was significantly associated with severe hearing loss and larger tumors.CONCLUSION: The presence of VS leads to a significant deterioration of audiovestibular function in all objective measures. Caloric test and o-VEMPS are sensitive though unspecific measures of VSs. Increasing tumor size is not directly associated with hearing loss and only somewhat to vestibular deficit. However, audiovestibular findings are correlated.

U2 - 10.5152/iao.2018.5500

DO - 10.5152/iao.2018.5500

M3 - Journal article

VL - 14

SP - 161

EP - 165

JO - Mediterranean Journal of Otology

JF - Mediterranean Journal of Otology

SN - 0022-2151

IS - 2

ER -

ID: 55863291