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Rigshospitalet - a part of Copenhagen University Hospital
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Antibiofilm Properties of Acetic Acid

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. An Equine Wound Model to Study Effects of Bacterial Aggregates on Wound Healing

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds

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  1. Minimum information guideline for spectrofotometric and fluorometric methods to assess biofilm formation in microplates

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  2. Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

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  3. Is pseudarthrosis after spinal instrumentation caused by a chronic infection?

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Bacterial biofilms are known to be extremely tolerant toward antibiotics and other antimicrobial agents. These biofilms cause the persistence of chronic infections. Since antibiotics rarely resolve these infections, the only effective treatment of chronic infections is surgical removal of the infected implant, tissue, or organ and thereby the biofilm. Acetic acid is known for its antimicrobial effect on bacteria in general, but has never been thoroughly tested for its efficacy against bacterial biofilms. In this article, we describe complete eradication of both Gram-positive and Gram-negative biofilms using acetic acid both as a liquid and as a dry salt. In addition, we present our clinical experience of acetic acid treatment of chronic wounds. In conclusion, we here present the first comprehensive in vitro and in vivo testing of acetic acid against bacterial biofilms.

Original languageEnglish
JournalAdvances in Wound Care
Volume4
Issue number7
Pages (from-to)363-372
Number of pages10
ISSN2162-1918
DOIs
Publication statusPublished - 1 Jul 2015

ID: 45583404