Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Aggressive multiple sclerosis (2): Treatment

Research output: Contribution to journalReviewpeer-review

DOI

  1. Exposure to passive smoking during adolescence is associated with an increased risk of developing multiple sclerosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. COVID-19 in people with multiple sclerosis: A global data sharing initiative

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Predictors of treatment outcome in patients with paediatric onset multiple sclerosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Reproductive history of the Danish multiple sclerosis population: A register-based study

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Exposure to passive smoking during adolescence is associated with an increased risk of developing multiple sclerosis

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Fibrinogen: A potential biomarker for predicting disease severity in multiple sclerosis

    Research output: Contribution to journalReviewpeer-review

  3. Using Smartphones and Wearable Devices to Monitor Behavioral Changes During COVID-19

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

The natural history of multiple sclerosis (MS) is highly heterogeneous. A subgroup of patients has what might be termed aggressive MS. These patients may have frequent, severe relapses with incomplete recovery and are at risk of developing greater and permanent disability at the earlier stages of the disease. Their therapeutic window of opportunity may be narrow, and while it is generally considered that they will benefit from starting early with a highly efficacious treatment, a unified definition of aggressive MS does not exist and data on its treatment are largely lacking. Based on discussions at an international focused workshop sponsored by the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), we review our current knowledge about treatment of individuals with aggressive MS. We analyse the available evidence, identify gaps in knowledge and suggest future research needed to fill those gaps. A companion paper details the difficulties in developing a consensus about what defines aggressive MS.

Original languageEnglish
JournalMultiple Sclerosis Journal
Volume26
Issue number9
Pages (from-to)1045-1063
ISSN1352-4585
DOIs
Publication statusPublished - 12 Jun 2020

    Research areas

  • Aggressive, highly active, multiple sclerosis, disability, relapsing-remitting, treatment response

ID: 61515402