Research output: Contribution to journal › Journal article › Research
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TY - JOUR
T1 - Acute recurrent polyhydramnios
T2 - a combination of amniocenteses and NSAID may be curative rather than palliative
AU - Rode, Line
AU - Bundgaard, Anne
AU - Skibsted, Lillian
AU - Odum, Lars
AU - Jørgensen, Connie
AU - Langhoff-Roos, Jens
N1 - (c) 2007 S. Karger AG, Basel.
PY - 2007
Y1 - 2007
N2 - Acute recurrent polyhydramnios is a rare occurrence characterized by a poor fetal outcome. This is a case report describing a 34-year-old woman presenting with acute recurrent polyhydramnios. Treatment with non-steroidal anti-inflammatory drugs (NSAID) and therapeutic amniocenteses was initiated immediately and resulted in a decreased amniotic fluid production from 30 weeks' gestation. Even after the discontinuation of NSAID treatment, the amniotic fluid production normalized, and the woman delivered a healthy boy at 39 weeks 2 days' gestation. Amniotic prolactin was measured at three occasions using an enzyme-linked immunosorbent assay. As in normal pregnancies, amniotic prolactin levels decreased by 80% from highest to lowest value in this case of resolving acute recurrent polyhydramnios.
AB - Acute recurrent polyhydramnios is a rare occurrence characterized by a poor fetal outcome. This is a case report describing a 34-year-old woman presenting with acute recurrent polyhydramnios. Treatment with non-steroidal anti-inflammatory drugs (NSAID) and therapeutic amniocenteses was initiated immediately and resulted in a decreased amniotic fluid production from 30 weeks' gestation. Even after the discontinuation of NSAID treatment, the amniotic fluid production normalized, and the woman delivered a healthy boy at 39 weeks 2 days' gestation. Amniotic prolactin was measured at three occasions using an enzyme-linked immunosorbent assay. As in normal pregnancies, amniotic prolactin levels decreased by 80% from highest to lowest value in this case of resolving acute recurrent polyhydramnios.
KW - Acute Disease
KW - Adult
KW - Amniocentesis
KW - Amniotic Fluid
KW - Anti-Inflammatory Agents, Non-Steroidal
KW - Combined Modality Therapy
KW - Female
KW - Humans
KW - Infant, Newborn
KW - Male
KW - Polyhydramnios
KW - Pregnancy
KW - Prolactin
KW - Receptors, Prolactin
KW - Recurrence
U2 - 10.1159/000098714
DO - 10.1159/000098714
M3 - Journal article
VL - 22
SP - 186
EP - 189
JO - Fetal Diagnosis and Therapy
JF - Fetal Diagnosis and Therapy
SN - 1015-3837
IS - 3
ER -
ID: 42353304