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Rigshospitalet - a part of Copenhagen University Hospital

Acute recurrent polyhydramnios: a combination of amniocenteses and NSAID may be curative rather than palliative

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Acute recurrent polyhydramnios is a rare occurrence characterized by a poor fetal outcome. This is a case report describing a 34-year-old woman presenting with acute recurrent polyhydramnios. Treatment with non-steroidal anti-inflammatory drugs (NSAID) and therapeutic amniocenteses was initiated immediately and resulted in a decreased amniotic fluid production from 30 weeks' gestation. Even after the discontinuation of NSAID treatment, the amniotic fluid production normalized, and the woman delivered a healthy boy at 39 weeks 2 days' gestation. Amniotic prolactin was measured at three occasions using an enzyme-linked immunosorbent assay. As in normal pregnancies, amniotic prolactin levels decreased by 80% from highest to lowest value in this case of resolving acute recurrent polyhydramnios.
Original languageEnglish
JournalFetal Diagnosis and Therapy
Issue number3
Pages (from-to)186-9
Number of pages4
Publication statusPublished - 2007

    Research areas

  • Acute Disease, Adult, Amniocentesis, Amniotic Fluid, Anti-Inflammatory Agents, Non-Steroidal, Combined Modality Therapy, Female, Humans, Infant, Newborn, Male, Polyhydramnios, Pregnancy, Prolactin, Receptors, Prolactin, Recurrence

ID: 42353304