Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

Abnormal prolactin levels and pituitary-gonadal axis in the puerperium

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Human Papillomavirus Genotypes From Vaginal and Vulvar Intraepithelial Neoplasia in Females 15-26 Years of Age

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Risk of Adverse Pregnancy Outcomes at Advanced Maternal Age

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Risk of Adverse Pregnancy Outcome After Paternal Exposure to Methotrexate Within 90 Days Before Pregnancy

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

To investigate the influence of breast-feeding and prolactin secretion on the pituitary-gonadal function, 3 different groups of patients were studied during the first 8 weeks of the puerperium. Group A comprised patients with hyperprolactinemia and secondary amenorrhea who conceived while on a regimen of bromocriptine. Group B was composed of normal lactating women. Group C comprised nonlactating women treated with bromocriptine. Group A patients had a normal decline in serum prolactin levels during the early postpartum period, but serum prolactin remained completely unaltered after clearance of placental estradiol. In group B suckling increased serum prolactin and suppressed luteinizing hormone. This pattern was not seen in group A. Group C patients had a rapid postpartum normalization of the pituitary-gonadal axis. The results indicate that in relation to lactation the pituitary function is rather autonomous in hyperprolactinemic patients.

Original languageEnglish
JournalObstetrics and Gynecology
Volume57
Issue number6
Pages (from-to)725-9
Number of pages5
ISSN0029-7844
Publication statusPublished - Jun 1981

    Research areas

  • Adult, Amenorrhea, Breast Feeding, Bromocriptine, Estrogens, Female, Humans, Lactation, Luteinizing Hormone, Ovary, Pituitary Gland, Pituitary Neoplasms, Postpartum Period, Pregnancy, Prolactin, Comparative Study, Journal Article

ID: 53710608