Research
Print page Print page
Switch language
Rigshospitalet - a part of Copenhagen University Hospital
Published

A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Natriuretic peptides and cerebral hemodynamics

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Adropin: a new regulatory peptide in cardiovascular endocrinology

    Research output: Contribution to journalJournal articleResearch

  4. Cardiac C-type natriuretic peptide gene expression and plasma concentrations in neonatal piglets

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Gut hormones - Team workers or solo trippers?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Colon polyps in patients with short bowel syndrome before and after teduglutide: Post hoc analysis of the STEPS study series

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Enteral Autonomy and Days Off Parenteral Support With Teduglutide Treatment for Short Bowel Syndrome in the STEPS Trials

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Repeated Metabolic Balance Studies in Patients With Short Bowel Syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Impact of Teduglutide on Quality of Life Among Patients With Short Bowel Syndrome and Intestinal Failure

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
Glucagon-like peptide 2 (GLP-2), secreted endogenously from L-cells in the distal bowel in relation to meals, modulates intestinal absorption by adjusting gastric emptying and secretion and intestinal growth. Short bowel syndrome (SBS) patients with distal intestinal resections have attenuated endogenous GLP-2 secretion, which may contribute to their rapid gastric emptying, gastric hypersecretion and poor intestinal adaptation, whereas SBS patients with preserved terminal ileum and colon, who have a constantly elevated GLP-2 secretion, seem to do better in these respects. This study compared effects of continuous, subcutaneous (s.c.), exogenous GLP-2 infusion (CONT-GLP-2) versus three daily s.c. GLP-2 injections (TID-GLP-2) on intestinal absorption in SBS patients.
Original languageEnglish
JournalRegulatory Peptides
Volume184
Pages (from-to)47-53
Number of pages7
ISSN0167-0115
DOIs
Publication statusPublished - 10 Jun 2013

ID: 42487565