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Rigshospitalet - a part of Copenhagen University Hospital
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A 5;7, 5;12 double reciprocal translocation in a normal mother and a 5;7 translocation with a recombinant chromosome 5 in her normal child

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  • A Tabor
  • L K Jensen
  • C Lundsteen
  • E Niebuhr
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A phenotypically normal mother had two apparently balanced translocations involving chromosomes 5, 7, and 12. Her karyotype was 46,XX,t(5;7) (5;12) (p14q34;p14;q21), while her daughter, who was also phenotypically normal, had inherited only one of the translocations. Her karyotype was 46,XX,-5,-7,+rec(5)t(5;7) (q34;p14)mat,+der(7)t(5;7) (q34;p14)mat. The other was lost during a meiotic crossing over, giving the daughter an apparently balanced chromosome complement.

Original languageEnglish
JournalJournal of Medical Genetics
Volume18
Issue number4
Pages (from-to)307-9
Number of pages3
ISSN0022-2593
Publication statusPublished - Aug 1981

    Research areas

  • Adult, Child, Preschool, Chromosomes, Human, 4-5, Chromosomes, Human, 6-12 and X, Female, Humans, Karyotyping, Phenotype, Translocation, Genetic, Uterine Cervical Diseases, Case Reports, Journal Article

ID: 53710662