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Rigshospitalet - a part of Copenhagen University Hospital
Niklas Rye Jørgensen

Niklas Rye Jørgensen

Professor, MD, DMSc, PhD

Valdemar Hansens Vej 13, indgang 3, VB, 2.sal

Building: Klinisk Biokemisk Afdeling, Rigshospitalet, Glostrup

2600 Glostrup

Denmark

  1. 2014
  2. Published

    Treatment of antipsychotic-associated obesity with a GLP-1 receptor agnoist: Protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study - the TAO study

    Ishøy, P. L., Knop, F. K., Broberg, B. V., Baandrup, L., Fagerlund, B., Jørgensen, N. R., Andersen, U. B., Rostrup, E., Glenthøj, B. Y. & Ebdrup, B. H., 8 Oct 2014. 1 p.

    Research output: Contribution to conferencePosterResearch

  3. Published

    Osteoblastic response to pectin nanocoating on titanium surfaces

    Gurzawska, K., Svava, R., Yihua, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Byg, I., Damager, I., Nielsen, M. W., Jørgensen, B., Jørgensen, N. R. & Gotfredsen, K., 1 Oct 2014, In : Materials Science and Engineering C: Materials for Biological Applications. 43, p. 117-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Muscle strength, power and cardiorespiratory fitness are associated with bone mineral density in men aged 31-60 years

    Schwarz, P., Jørgensen, N., Nielsen, B., Laursen, A. S. D., Linneberg, A. & Aadahl, M., 30 Sep 2014, In : Scandinavian Journal of Public Health. 42, 8, p. 773-779

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Genetic variants in the P2RX7 gene are associated with risk of multiple myeloma

    Vangsted, A. J., Klausen, T. W., Gimsing, P., Abildgaard, N., Andersen, N. F., Gang, A. O., Holmström, M. O., Gregersen, H., Vogel, U., Schwarz, P. & Jørgensen, N. R., Aug 2014, In : European Journal of Haematology. 93, 2, p. 172-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Recreational football improves bone mineral density and bone turnover marker profile in elderly men

    Helge, E. W., Andersen, T. R., Schmidt, J. F., Jørgensen, N. R., Hornstrup, T., Krustrup, P. & Bangsbo, J., Aug 2014, In : Scandinavian journal of medicine & science in sports. 24 Suppl 1, p. 98-104 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The structurally effect of surface coated rhamnogalacturonan I on response of the osteoblast-like cell line SaOS-2

    Svava, R., Gurzawska, K., Yihau, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Jørgensen, N. R., Gotfredsen, K., Damager, I., Ulvskov, P. & Jørgensen, B., Jun 2014, In : Journal of Biomedical Materials Research. Part A. 102, 6, p. 1961-1971 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Status of drug development for the prevention and treatment of osteoporosis

    Schwarz, P., Jørgensen, N. R. & Abrahamsen, B., Mar 2014, In : Expert Opinion on Drug Discovery. 9, 3, p. 245-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Treatment of antipsychotic-associated obesity with a GLP-1 receptor agonist: Protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study – the TAO study

    Ishøy, P. L., Knop, F. K., Broberg, B. V., Baandrup, L., Fagerlund, B., Jørgensen, N. R., Andersen, U. B., Rostrup, E., Glenthøj, B. Y. & Ebdrup, B. H., Mar 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  10. Published

    Plasma plasminogen activator inhibitor-1 predicts myocardial infarction in HIV-1-infected individuals

    Knudsen, A., Katzenstein, T. L., Benfield, T., Jørgensen, N. R., Kronborg, G., Gerstoft, J., Obel, N., Kjær, A. & Lebech, A-M., 22 Feb 2014, In : AIDS (London, England). 28, 8, p. 1171-79

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Non-infectious osteomyelitis of the mandible in a young woman: a case report

    Rasmussen, A. Q., Andersen, U. B., Jørgensen, N. R. & Schwarz, P., 12 Feb 2014, In : Journal of Medical Case Reports. 8, 1, p. 44

    Research output: Contribution to journalJournal articleResearch

  12. Published

    Carriers in mesenchymal stem cell osteoblast mineralization--state-of-the-art

    Dahl, M., Jørgensen, N. R., Hørberg, M. & Pinholt, E. M., Jan 2014, In : Journal of Cranio-Maxillofacial Surgery. 42, 1, p. 41-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The P2X7 Receptor: A Key Player in Immune-Mediated Bone Loss?

    Kvist, T. M., Schwarz, P. & Jørgensen, N. R., 2014, In : TheScientificWorldJournal. 2014, p. 954530

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Treatment of antipsychotic-associated obesity with a GLP-1 receptor agonist--protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study: the TAO study protocol

    Ishøy, P. L., Knop, F. K., Broberg, B. V., Baandrup, L., Fagerlund, B., Jørgensen, N. R., Andersen, U. B., Rostrup, E., Glenthøj, B. Y. & Ebdrup, B. H., 2014, In : B M J Open. 4, 1, p. e004158

    Research output: Contribution to journalJournal articleResearch

  15. Published

    UTP-induced ATP release is a fine-tuned signalling pathway in osteocytes

    Kringelbach, T. M., Aslan, D., Novak, I., Schwarz, P. & Jørgensen, N. R., 2014, In : Purinergic Signalling. 10, 2, p. 337-347

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2013
  17. Published

    Adipose derived mesenchymal stem cells - Their osteogenicity and osteoblast in vitro mineralization on titanium granule carriers

    Dahl, M., Syberg, S., Jørgensen, N. R. & Pinholt, E. M., Dec 2013, In : Journal of Cranio-Maxillofacial Surgery. 41, 8, p. e213-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Association of P2Y(2) receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, P., Jørgensen, N. R., van Helden, S. & Dagnelie, P. C., Mar 2013, In : Purinergic Signalling. 9, 1, p. 41-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Functional polymorphisms in the P2X7 receptor gene are associated with osteoporosis

    Husted, L. B., Harsløf, T., Stenkjær, L., Carstens, M., Jørgensen, N. R. & Langdahl, B. L., Mar 2013, In : Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 24, 3, p. 949-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J., Jørgensen, N. R., Wiley, J., Gu, B., van Helden, S., van Rhijn, L. & Dagnelie, P. C., Mar 2013, In : Purinergic Signalling. 9, 1, p. 123-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Gastrointestinal events with clopidogrel: a nationwide population-based cohort study

    Grove, E. L., Würtz, M., Schwarz, P., Jørgensen, N. R. & Vestergaard, P., Feb 2013, In : Journal of General Internal Medicine. 28, 2, p. 216-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Association of P2X(7) receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, P., Jørgensen, N. R., van Helden, S. & Dagnelie, P. C., 2013, In : Osteoporosis International. 24, 4, p. 1235-1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Purinergic signaling in bone

    Jørgensen, N. R., Adinolfi, E., Orriss, I. & Schwarz, P., 2013, In : Journal of Osteoporosis. 2013, p. 673684

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    The effect of PTH(1-34) on fracture healing during different loading conditions.

    Ellegaard Larsen, M., Kringelbach, T., Syberg, S., Petersen, S., Beck Jensen, J-E., Brüel, A., Jørgensen, N. R. & Schwarz, P., 2013, In : Journal of Bone and Mineral Research. 28, 10, p. 2145-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2012
  27. Published

    Association between P2X7 Receptor Polymorphisms and Bone Status in Mice

    Syberg, S., Schwarz, P., Petersen, S., Steinberg, T. H., Jensen, J-E. B., Teilmann, J. & Jørgensen, N. R., 2012, In : Journal of Osteoporosis. 2012, p. 637986

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Clopidogrel (Plavix®), a P2Y(12) receptor antagonist, inhibits bone cell function in vitro and decreases trabecular bone in vivo

    Syberg, S., Brandao-Burch, A., Patel, J. J., Hajjawi, M., Arnett, T. R., Schwarz, P., Jørgensen, N. R. & Orriss, I. R., 2012, In : Journal of Bone and Mineral Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Clopidogrel and the risk of osteoporotic fractures: a nationwide cohort study

    Jørgensen, N. R., Grove, E. L., Schwarz, P. & Vestergaard, P., 2012, In : Journal of Internal Medicine. 272/4, p. 385-393

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Effect of nanocoating with rhamnogalacturonan-I on surface properties and osteoblasts response

    Gurzawska, K., Svava, R., Syberg, S., Yihua, Y., Haugshøj, K. B., Damager, I., Ulvskov, P., Christensen, L. H., Gotfredsen, K. & Jørgensen, N. R., 2012, In : Journal of Biomedical Materials Research. Part A. 100, 3, p. 654-64 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Effects of Increasing Age, Dosage, and Duration of PTH Treatment on BMD Increase-A Meta-analysis

    Schwarz, P., Jorgensen, N. R., Mosekilde, L. & Vestergaard, P., 2012, In : Calcified Tissue International. 90, 3, p. 165-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice

    Syberg, S., Petersen, S., Beck Jensen, J-E., Gartland, A., Teilmann, J., Chessell, I., Steinberg, T. H., Schwarz, P. & Jørgensen, N. R., 2012, In : Journal of Osteoporosis. 2012, p. 391097

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Mechanisms for the bone anabolic effect of parathyroid hormone treatment in humans

    Aslan, D., Andersen, M. D., Gede, L. B., de Franca, T. K., Jørgensen, S. R., Schwarz, P. & Jørgensen, N. R., 2012, In : Scandinavian Journal of Clinical & Laboratory Investigation. 72, 1, p. 14-22 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Nanocoating of titanium implant surfaces with organic molecules. Polysaccharides including glycosaminoglycans

    Gurzawska, K., Svava, R., Jørgensen, N. R. & Gotfredsen, K., 2012, In : Journal of Biomedical Nanotechnology. 8, 6, p. 1012-24 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Paget's disease of the bone after treatment with Denosumab: a case report

    Schwarz, P., Rasmussen, A. Q., Kvist, T. M., Andersen, U. B. & Jørgensen, N. R., 2012, In : The Bone. 50, 5, p. 1023-5 3 p.

    Research output: Contribution to journalJournal articleResearch

  36. Published

    Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

    Gartland, A., Skarratt, K. K., Hocking, L. J., Parsons, C., Stokes, L., Jørgensen, N. R., Fraser, W. D., Reid, D. M., Gallagher, J. A. & Wiley, J. S., 2012, In : European Journal of Human Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

    Jørgensen, N. R., Husted, L. B., Skarratt, K. K., Stokes, L., Tofteng, C. L., Kvist, T., Jensen, J-E. B., Eiken, P., Brixen, K. T., Fuller, S., Clifton-Bligh, R., Gartland, A., Schwarz, P., Langdahl, B. L. & Wiley, J. S., 2012, In : European Journal of Human Genetics. 20, p. 675-681

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Use of the oral platelet inhibitors dipyridamole and acetylsalicylic acid is associated with increased risk of fracture

    Vestergaard, P., Steinberg, T. H., Schwarz, P. & Jørgensen, N. R., 2012, In : International Journal of Cardiology. 160, 1, p. 36-40 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2011
  40. Published

    Role of purinergic receptor polymorphisms in human bone

    Wesselius, A., Bours, M. J. L., Agrawal, A., Gartland, A., Dagnelie, P. C., Schwarz, P. & Jørgensen, N. R., 1 Jan 2011, In : Frontiers in bioscience : a journal and virtual library. 17, p. 2572-85 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Bone mineral density difference between right and left hip during ageing

    Schwarz, P., Jørgensen, N. R., Jensen, L. T. & Vestergaard, P., 2011, In : European Geriatric Medicine. 2, 2, p. 82 - 86

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Bone phenotypes of P2 receptor knockout mice

    Orriss, I., Syberg, S., Wang, N., Robaye, B., Gartland, A., Jorgensen, N., Arnett, T. & Boeynaems, J-M., 2011, In : Frontiers in Bioscience (Scholar Edition). 3, p. 1038-46 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Clinical and biochemical outcomes of cinacalcet treatment of familial hypocalciuric hypercalcemia: a case series

    Rasmussen, A. Q., Jørgensen, N. R. & Schwarz, P., 2011, In : Journal of Medical Case Reports. 5, 1, p. 564

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effects of anti-osteoporosis medications on fracture healing

    Jørgensen, N. R. & Schwarz, P., 2011, In : Current Osteoporosis Reports (Online). 9, 3, p. 149-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    European meeting "P2 receptors: new targets for the treatment of osteoporosis"

    Jørgensen, N. R., Boeynaems, J-M. & Di Virgilio, F., 2011, In : Purinergic Signalling. 7, 2, p. 275-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    P2X7 receptor-deficient mice are susceptible to bone cancer pain

    Hansen, R. R., Nielsen, C., Nasser, A., Thomsen, S. I. M., Eghorn, L. F., Pham, T. N. Y., Schulenburg, C., Syberg, S., Ding, M., Stojilkovic, S. S., Jorgensen, N. R. & Heegaard, A-M., 2011, In : Pain. 152, 8, p. 1766-76 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The evidence for efficacy of osteoporosis treatment in men with primary osteoporosis: a systematic review and meta-analysis of antiresorptive and anabolic treatment in men

    Schwarz, P., Jorgensen, N. R., Mosekilde, L. & Vestergaard, P., 2011, In : Journal of Osteoporosis. 2011, p. 259818

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2010
  49. Published

    Parathyroid hormone and bone healing

    Ellegaard, M., Jørgensen, N. R. & Schwarz, P., 1 Jul 2010, In : Calcified Tissue International. 87, 1, p. 1-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Amylin(1-8) is devoid of anabolic activity in bone

    Ellegaard, M., Thorkildsen, C., Vibe-Petersen, S., Petersen, J. S., Jørgensen, N. R., Just, R., Schwarz, P., Ramirez, M. T. & Stahlhut, M., 1 Mar 2010, In : Calcified Tissue International. 86, 3, p. 249-60 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2007
  52. Published

    Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment

    Ohlendorff, S. D., Tofteng, C. L., Jensen, J-E. B., Petersen, S., Civitelli, R., Fenger, M., Abrahamsen, B., Hermann, A. P., Eiken, P., Jørgensen, N. R. & Jrgensen, N. R., 1 Jul 2007, In : Pharmacogenetics and Genomics. 17, 7, p. 555-67 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 30792