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Rigshospitalet - a part of Copenhagen University Hospital
Niklas Rye Jørgensen

Niklas Rye Jørgensen

Professor, MD, DMSc, PhD

Valdemar Hansens Vej 13, indgang 3, VB, 2.sal

Building: Klinisk Biokemisk Afdeling, Rigshospitalet, Glostrup

2600 Glostrup

Denmark

  1. 2017
  2. Published

    Bone structural changes after gastric bypass surgery evaluated by HR-pQCT: a two-year longitudinal study

    Shanbhogue, V. V., Støving, R. K., Frederiksen, K. H., Hanson, S., Brixen, K., Gram, J., Jørgensen, N. R. & Hansen, S., Jun 2017, In : European Journal of Endocrinology. 176, 6, p. 685-693 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: a single-arm phase II trial

    Kjær Nielsen, T., Højgaard, M., Andersen, J. T., Jørgensen, N. R., Zerahn, B., Kristensen, B., Henriksen, T., Lykkesfeldt, J., Mikines, K. J. & Poulsen, H. E., Jun 2017, In : Translational Andrology and Urology. 6, 3, p. 517-528 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Clinical usefulness of bone turnover marker concentrations in osteoporosis

    Morris, H. A., Eastell, R., Jorgensen, N. R., Cavalier, E., Vasikaran, S., Chubb, S. A. P., Kanis, J. A., Cooper, C., Makris, K. & IFCC-IOF Working Group for Standardisation of Bone Marker Assays (WG-BMA), Apr 2017, In : Clinica chimica acta; international journal of clinical chemistry. 467, p. 34-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pectin nanocoating of titanium implant surfaces - an experimental study in rabbits

    Gurzawska, K., Dirscherl, K., Jørgensen, B., Berglundh, T., Jørgensen, N. R. & Gotfredsen, K., Mar 2017, In : Clinical Oral Implants Research. 28, 3, p. 298-307 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts

    Agrawal, A., Henriksen, Z., Syberg, S., Petersen, S., Aslan, D., Solgaard, M., Nissen, N., Korsgaard Larsen, T., Schwarz, P., Steinberg, T. H. & Jørgensen, N. R., Feb 2017, In : Bone. 95, p. 91-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Adaptations with Intermittent Exercise Training in Post- and Premenopausal Women

    Seidelin, K., Nyberg, M., Piil, P., Jørgensen, N. R., Hellsten, Y. & Bangsbo, J., Jan 2017, In : Medicine and Science in Sports and Exercise. 49, 1, p. 96-105 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of GLP-1 Receptor Agonist Treatment on Body weight in Obese Antipsychotic-treated Patients with Schizophrenia: a Randomized, Placebo-controlled Trial Byline

    Ishøy, P. L., Knop, F. K., Broberg, B. V., Bak, N., Andersen, U. B., Jørgensen, N. R., Holst, J. J., Glenthøj, B. Y. & Ebdrup, B. H., 2017, In : Diabetes, Obesity and Metabolism. 19, 2, p. 162-171

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Evidence for the prevention of bone loss in elderly and old early non-metastatic breast cancer patients treated with aromatase inhibitors

    Gunmalm, V., Jørgensen, N. R., Abrahamsen, B. & Schwarz, P., 2017, In : European Geriatric Medicine. 8, p. 408-412 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    P2Y12 Receptor Antagonist, Clopidogrel, Does Not Contribute to Risk of Osteoporotic Fractures in Stroke Patients

    Jørgensen, N. R., Schwarz, P., Iversen, H. K. & Vestergaard, P., 2017, In : Frontiers in Pharmacology. 8, p. e821

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Reliability of the Biochemical Bone Markers CTX and P1NP during a TNF-Inhibitor Treatment Cycle in Patients with Rheumatoid Arthritis

    Holmsted, K., Jørgensen, N. R. & Madsen, O. R., 2017, In : Arthritis & Rheumatology. 69, S10, 2382.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  12. 2016
  13. Published

    Soluble urokinase plasminogen activator receptor (suPAR) is a novel, independent predictive marker of myocardial infarction in HIV-1-infected patients: a nested case-control study

    Jee Hartmann Rasmussen, L., Knudsen, A., Katzenstein, T. L., Gerstoft, J., Obel, N., Jørgensen, N. R., Kronborg, G., Benfield, T., Kjaer, A., Eugen-Olsen, J. & Lebech, A-M., May 2016, In : HIV Medicine. 17, 5, p. 350-357

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Bone Structural Changes and Estimated Strength After Gastric Bypass Surgery Evaluated by HR-pQCT

    Frederiksen, K. D., Hanson, S., Hansen, S., Brixen, K., Gram, J., Jørgensen, N. R. & Støving, R. K., Mar 2016, In : Calcified Tissue International. 98, 3, p. 253-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Football training in men with prostate cancer undergoing androgen deprivation therapy activity profile and short-term skeletal and postural balance adaptations

    Uth, J., Hornstrup, T., Christensen, J. F., Christensen, K. B., Jørgensen, N. R., Helge, E. W., Schmidt, J. F., Brasso, K., Helge, J. W., Jakobsen, M. D., Andersen, L. L., Rørth, M., Midtgaard, J. & Krustrup, P., Mar 2016, In : European Journal of Applied Physiology. 116, 3, p. 471-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Compromised cortical bone compartment in type 2 diabetes mellitus patients with microvascular disease

    Shanbhogue, V. V., Hansen, S., Frost, M., Jørgensen, N. R., Hermann, A. P., Henriksen, J. E. & Brixen, K., Feb 2016, In : European Journal of Endocrinology. 174, 2, p. 115-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    New insights on pyrimidine signalling within the arterial vasculature - Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse

    Haanes, K. A., Spray, S., Syberg, S., Jørgensen, N. R., Robaye, B., Boeynaems, J-M. & Edvinsson, L., 28 Jan 2016, In : Journal of Molecular and Cellular Cardiology. 93, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A Comprehensive Fracture Prevention Strategy in Older Adults: The European Union Geriatric Medicine Society (EUGMS) Statement

    EUGMS Falls and Fracture Interest Group, The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and International osteoporosis Foundation (IOF) (Niklas Rye Jørgensen, member) & Jørgensen, N. R., 2016, In : Journal of Nutrition, Health and Aging. 20, 6, p. 647-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Short Duration Small Sided Football and to a Lesser Extent Whole Body Vibration Exercise Induce Acute Changes in Markers of Bone Turnover

    Bowtell, J. L., Jackman, S. R., Scott, S., Connolly, L. J., Mohr, M., Ermidis, G., Julian, R., Yousefian, F., Helge, E. W., Jørgensen, N. R., Fulford, J., Knapp, K. M. & Krustrup, P., 2016, In : BioMed Research International. 2016, p. 3574258

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2015
  22. Published

    Effects of soccer vs swim training on bone formation in sedentary middle-aged women

    Mohr, M., Helge, E. W., Petersen, L. F., Lindenskov, A., Weihe, P., Mortensen, J., Jørgensen, N. R. & Krustrup, P., Dec 2015, In : European Journal of Applied Physiology. 115, 12, p. 2671-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Fine-tuned ATP signals are acute mediators in osteocyte mechanotransduction

    Kringelbach, T. M., Aslan, D., Novak, I., Ellegaard, M., Syberg, S., Andersen, C. K. B., Kristiansen, K. A., Vang, O., Schwarz, P. & Jørgensen, N. R., Dec 2015, In : Cellular Signalling. 27, 12, p. 2401-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    No changes in serum tryptase after bariatric surgery

    Skaaby, T., Vestergaard, H., Thomsen, S., Knudsen, A. L., Jørgensen, N. & Linneberg, A., Oct 2015, In : Annals of Epidemiology. 25, 10, p. 800-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The Impact of Nocturnal Hypoglycemia on Sleep in Subjects With Type 2 Diabetes

    Jennum, P., Stender-Petersen, K. L., Rabøl, R., Jørgensen, N. R., Chu, P-L. & Madsbad, S., Oct 2015, In : Diabetes Care. 38, 11, p. 2151-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    GLP-1 Receptor Agonist Treatment Increases Bone Formation and Prevents Bone Loss in Weight-Reduced Obese Women

    Iepsen, E. W., Lundgren, J. R., Hartmann, B., Pedersen, O., Hansen, T., Jørgensen, N. R., Jensen, J-E. B., Holst, J. J., Madsbad, S. & Torekov, S. S., Aug 2015, In : The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Bone Geometry, Volumetric Density, Microarchitecture, and Estimated Bone Strength Assessed by HR-pQCT in Adult Patients With Type 1 Diabetes Mellitus

    Shanbhogue, V. V., Hansen, S., Frost, M., Jørgensen, N. R., Hermann, A. P., Henriksen, J. E. & Brixen, K., 10 Jun 2015, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 12, p. 2188-99

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Application of high resolution synchrotron micro-CT radiation in dental implant osseointegration

    Neldam, C. A., Lauridsen, T., Rack, A., Lefolii, T. T., Jørgensen, N. R., Feidenhans'l, R. & Pinholt, E. M., Jun 2015, In : Journal of Cranio-Maxillofacial Surgery. 43, 5, p. 682-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7

    Adinolfi, E., Capece, M., Franceschini, A., Falzoni, S., Giuliani, A. L., Rotondo, A., Sarti, A. C., Bonora, M., Syberg, S., Corigliano, D., Pinton, P., Jorgensen, N. R., Abelli, L., Emionite, L., Raffaghello, L., Pistoia, V. & Di Virgilio, F., 15 Feb 2015, In : Cancer Research. 75, 4, p. 635-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published
  31. Published
  32. Published

    Exercise and Regulation of Bone and Collagen Tissue Biology

    Kjaer, M., Jørgensen, N. R., Heinemeier, K. & Magnusson, S. P., 2015, In : Progress in Molecular Biology and Translational Science. 135, p. 259-91 33 p.

    Research output: Contribution to journalJournal articleCommunication

  33. Published

    High-dose ascorbic acid in metastatic castration-resistant prostate cancer: evalution of efficacy and safety in a phase II trial.

    Kjær Nielsen, T., Højgaard, M., Poulsen, H. E., Lykkesfeldt, J., Jørgensen, N. R. & Mikines, K. J., 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  34. Published

    The role of P2X receptors in bone biology

    Jørgensen, N. R., Syberg, S. & Ellegaard, M., 2015, In : Current Medicinal Chemistry. 22, 7, p. 902-14 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2014
  36. Published

    Bone geometry, volumetric density, microarchitecture, and estimated bone strength assessed by HR-pQCT in Klinefelter syndrome

    Shanbhogue, V. V., Hansen, S., Jørgensen, N. R., Brixen, K. & Gravholt, C. H., Nov 2014, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 11, p. 2474-82 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Treatment of antipsychotic-associated obesity with a GLP-1 receptor agnoist: Protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study - the TAO study

    Ishøy, P. L., Knop, F. K., Broberg, B. V., Baandrup, L., Fagerlund, B., Jørgensen, N. R., Andersen, U. B., Rostrup, E., Glenthøj, B. Y. & Ebdrup, B. H., 8 Oct 2014. 1 p.

    Research output: Contribution to conferencePosterResearch

  38. Published

    Osteoblastic response to pectin nanocoating on titanium surfaces

    Gurzawska, K., Svava, R., Yihua, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Byg, I., Damager, I., Nielsen, M. W., Jørgensen, B., Jørgensen, N. R. & Gotfredsen, K., 1 Oct 2014, In : Materials Science and Engineering C: Materials for Biological Applications. 43, p. 117-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Muscle strength, power and cardiorespiratory fitness are associated with bone mineral density in men aged 31-60 years

    Schwarz, P., Jørgensen, N., Nielsen, B., Laursen, A. S. D., Linneberg, A. & Aadahl, M., 30 Sep 2014, In : Scandinavian Journal of Public Health. 42, 8, p. 773-779

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Genetic variants in the P2RX7 gene are associated with risk of multiple myeloma

    Vangsted, A. J., Klausen, T. W., Gimsing, P., Abildgaard, N., Andersen, N. F., Gang, A. O., Holmström, M. O., Gregersen, H., Vogel, U., Schwarz, P. & Jørgensen, N. R., Aug 2014, In : European Journal of Haematology. 93, 2, p. 172-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Recreational football improves bone mineral density and bone turnover marker profile in elderly men

    Helge, E. W., Andersen, T. R., Schmidt, J. F., Jørgensen, N. R., Hornstrup, T., Krustrup, P. & Bangsbo, J., Aug 2014, In : Scandinavian journal of medicine & science in sports. 24 Suppl 1, p. 98-104 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The structurally effect of surface coated rhamnogalacturonan I on response of the osteoblast-like cell line SaOS-2

    Svava, R., Gurzawska, K., Yihau, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Jørgensen, N. R., Gotfredsen, K., Damager, I., Ulvskov, P. & Jørgensen, B., Jun 2014, In : Journal of Biomedical Materials Research. Part A. 102, 6, p. 1961-1971 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Status of drug development for the prevention and treatment of osteoporosis

    Schwarz, P., Jørgensen, N. R. & Abrahamsen, B., Mar 2014, In : Expert Opinion on Drug Discovery. 9, 3, p. 245-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Treatment of antipsychotic-associated obesity with a GLP-1 receptor agonist: Protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study – the TAO study

    Ishøy, P. L., Knop, F. K., Broberg, B. V., Baandrup, L., Fagerlund, B., Jørgensen, N. R., Andersen, U. B., Rostrup, E., Glenthøj, B. Y. & Ebdrup, B. H., Mar 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  45. Published

    Plasma plasminogen activator inhibitor-1 predicts myocardial infarction in HIV-1-infected individuals

    Knudsen, A., Katzenstein, T. L., Benfield, T., Jørgensen, N. R., Kronborg, G., Gerstoft, J., Obel, N., Kjær, A. & Lebech, A-M., 22 Feb 2014, In : AIDS (London, England). 28, 8, p. 1171-79

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Non-infectious osteomyelitis of the mandible in a young woman: a case report

    Rasmussen, A. Q., Andersen, U. B., Jørgensen, N. R. & Schwarz, P., 12 Feb 2014, In : Journal of Medical Case Reports. 8, 1, p. 44

    Research output: Contribution to journalJournal articleResearch

  47. Published

    Carriers in mesenchymal stem cell osteoblast mineralization--state-of-the-art

    Dahl, M., Jørgensen, N. R., Hørberg, M. & Pinholt, E. M., Jan 2014, In : Journal of Cranio-Maxillofacial Surgery. 42, 1, p. 41-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The P2X7 Receptor: A Key Player in Immune-Mediated Bone Loss?

    Kvist, T. M., Schwarz, P. & Jørgensen, N. R., 2014, In : TheScientificWorldJournal. 2014, p. 954530

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Treatment of antipsychotic-associated obesity with a GLP-1 receptor agonist--protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded intervention study: the TAO study protocol

    Ishøy, P. L., Knop, F. K., Broberg, B. V., Baandrup, L., Fagerlund, B., Jørgensen, N. R., Andersen, U. B., Rostrup, E., Glenthøj, B. Y. & Ebdrup, B. H., 2014, In : B M J Open. 4, 1, p. e004158

    Research output: Contribution to journalJournal articleResearch

  50. Published

    UTP-induced ATP release is a fine-tuned signalling pathway in osteocytes

    Kringelbach, T. M., Aslan, D., Novak, I., Schwarz, P. & Jørgensen, N. R., 2014, In : Purinergic Signalling. 10, 2, p. 337-347

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2013
  52. Published

    Adipose derived mesenchymal stem cells - Their osteogenicity and osteoblast in vitro mineralization on titanium granule carriers

    Dahl, M., Syberg, S., Jørgensen, N. R. & Pinholt, E. M., Dec 2013, In : Journal of Cranio-Maxillofacial Surgery. 41, 8, p. e213-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Association of P2Y(2) receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, P., Jørgensen, N. R., van Helden, S. & Dagnelie, P. C., Mar 2013, In : Purinergic Signalling. 9, 1, p. 41-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Functional polymorphisms in the P2X7 receptor gene are associated with osteoporosis

    Husted, L. B., Harsløf, T., Stenkjær, L., Carstens, M., Jørgensen, N. R. & Langdahl, B. L., Mar 2013, In : Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 24, 3, p. 949-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J., Jørgensen, N. R., Wiley, J., Gu, B., van Helden, S., van Rhijn, L. & Dagnelie, P. C., Mar 2013, In : Purinergic Signalling. 9, 1, p. 123-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 30792