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Rigshospitalet - a part of Copenhagen University Hospital
Niklas Rye Jørgensen

Niklas Rye Jørgensen

Professor, MD, DMSc, PhD

Valdemar Hansens Vej 13, indgang 3, VB, 2.sal

Building: Klinisk Biokemisk Afdeling, Rigshospitalet, Glostrup

2600 Glostrup

Denmark

  1. 2020
  2. Published

    GIP's effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3-30)NH2

    Gasbjerg, L. S., Hartmann, B., Christensen, M. B., Lanng, A. R., Vilsbøll, T., Jørgensen, N. R., Holst, J. J., Rosenkilde, M. M. & Knop, F. K., 1 Jan 2020, In : The Bone. 130, 115079.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients

    Ellegaard, M., Bieler, T., Beyer, N., Kjaer, M. & Jørgensen, N. R., 1 Jan 2020, In : Translational Sports Medicine. 3, 1, p. 16-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2019
  5. E-pub ahead of print

    Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, A. K., Jørgensen, N. R., Olsen, B. S., Svensson, J., Pociot, F. & Johannesen, J., 15 Dec 2019, In : Pediatric Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Biochemical markers of inflammation are associated with increased mortality in hip fracture patients: the Bispebjerg Hip Fracture Biobank

    Norring-Agerskov, D., Bathum, L., Pedersen, O. B., Abrahamsen, B., Lauritzen, J. B., Jørgensen, N. R. & Jørgensen, H. L., 1 Dec 2019, In : Aging clinical and experimental research. 31, 12, p. 1727-1734 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Fracture-induced changes in biomarkers CTX, PINP, OC, and BAP - a systematic review

    Højsager, F. D., Rand, M. S., Pedersen, S. B., Nissen, N. & Jørgensen, N. R., Dec 2019, In : Osteoporosis International. 30, 12, p. 2381-2389 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published
  9. Published

    Multiple Fractures and Impaired Bone Fracture Healing in a Patient with Pycnodysostosis and Hypophosphatasia

    Hepp, N., Frederiksen, A. L., Dunø, M., Jørgensen, N. R., Langdahl, B., Hove, H. B., Vedtofte, P., Hindsø, K. & Jensen, J-E. B., Dec 2019, In : Calcified Tissue International. 105, 6, p. 681-686 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. E-pub ahead of print

    Unaffected bone mineral density in Danish children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, A. K., Jørgensen, N. R., Olsen, B. S., Pociot, F. & Johannesen, J., 21 Nov 2019, In : Journal of Bone and Mineral Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Assessment of acute bone loading in humans using [18F]NaF PET/MRI

    Haddock, B., Fan, A. P., Uhlrich, S. D., Jørgensen, N. R., Suetta, C., Gold, G. E. & Kogan, F., Nov 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, 12, p. 2452-2463 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Algorithm for the use of biochemical markers of bone turnover in the diagnosis, assessment and follow-up of treatment for osteoporosis

    Lorentzon, M., Branco, J., Brandi, M. L., Bruyère, O., Chapurlat, R., Cooper, C., Cortet, B., Diez-Perez, A., Ferrari, S., Gasparik, A., Herrmann, M., Jorgensen, N. R., Kanis, J., Kaufman, J-M., Laslop, A., Locquet, M., Matijevic, R., McCloskey, E., Minisola, S., Pikner, R., Reginster, J-Y., Rizzoli, R., Szulc, P., Vlaskovska, M. & Cavalier, E., Oct 2019, In : Advances in Therapy. 36, 10, p. 2811-2824 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study): a randomized controlled trial

    Jepsen, D. B., Ryg, J., Hansen, S., Jørgensen, N. R., Gram, J. & Masud, T., Sep 2019, In : Osteoporosis International. 30, 9, p. 1827-1836 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. E-pub ahead of print

    Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass

    Iepsen, E. W., Zhang, J., Hollensted, M., Madsbad, S., Hansen, T., Holst, J. J., Jørgensen, N. R., Holm, J-C. & Torekov, S. S., 30 Aug 2019, In : Journal of Bone and Mineral Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Bone turnover markers in children and adolescents with type 1 diabetes - A systematic review

    Madsen, J. O. B., Jørgensen, N. R., Pociot, F. & Johannesen, J., 1 Aug 2019, In : Pediatric Diabetes. 20, 5, p. 510-522 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Role of the purinergic P2X receptors in osteoclast pathophysiology

    Jørgensen, N. R., Aug 2019, In : Current Opinion in Pharmacology. 47, p. 97-101 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes

    Bergmann, N. C., Lund, A., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M. B., Vilsbøll, T. & Knop, F. K., Jul 2019, In : The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953-2960 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    An evaluation of total 25-hydroxyvitamin D assay standardization: Where are we today?

    Bjerg, L. N., Halgreen, J. R., Hansen, S. H., Morris, H. A. & Jørgensen, N. R., Jun 2019, In : The Journal of steroid biochemistry and molecular biology. 190, p. 224-233 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Bone health in patients with type 2 diabetes treated by Roux-En-Y gastric bypass and the role of diabetes remission

    Madsen, L. R., Espersen, R., Ornstrup, M. J., Jørgensen, N. R., Langdahl, B. L. & Richelsen, B., Jun 2019, In : Obesity Surgery. 29, 6, p. 1823-1831 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Elevated bone remodeling markers of CTX and P1NP in addition to sclerostin in patients with X-linked hypophosphatemia: A Cross-Sectional Controlled Study

    Hansen, S., Shanbhogue, V. V., Jørgensen, N. R. & Beck-Nielsen, S. S., Jun 2019, In : Calcified Tissue International. 104, 6, p. 591-598 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

    Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, N. R., Vestergaard, H., Hansen, T., Hansen, T. H., Pedersen, O. & Nielsen, T., Jun 2019, In : Diabetologia. 62, 6, p. 1024-1035 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors

    Eickhoff, M. K., Dekkers, C. C. J., Kramers, B. J., Laverman, G. D., Frimodt-Møller, M., Jørgensen, N. R., Faber, J., Danser, A. H. J., Gansevoort, R. T., Rossing, P., Persson, F. & Heerspink, H. J. L., 31 May 2019, In : Journal of Clinical Medicine. 8, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Bone mass development is sensitive to insulin resistance in adolescent boys

    Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Bugge, A., Laursen, J. O., Jørgensen, N. R., Husby, S., Wedderkopp, N. & Mølgaard, C., May 2019, In : Bone. 122, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Bone turnover markers are differentially affected by pre-analytical handling

    Christensen, G. L., Halgreen, J. R., Milenkovski, M., Köse, A., Quardon, N. & Jørgensen, N. R., May 2019, In : Osteoporosis International. 30, 5, p. 1137-1141 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Kinetic [18F]-Fluoride of the knee in normal volunteers

    Haddock, B., Fan, A. P., Jørgensen, N. R., Suetta, C., Gold, G. E. & Kogan, F., May 2019, In : Clinical Nuclear Medicine. 44, 5, p. 377-385 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published
  27. Published

    Calcitonin-gene related peptide and disease activity in cluster headache

    Snoer, A., Vollesen, A. L. H., Beske, R. P., Guo, S., Hoffmann, J., Fahrenkrug, J., Jørgensen, N. R., Martinussen, T., Jensen, R. H. & Ashina, M., Apr 2019, In : Cephalalgia : an international journal of headache. 39, 5, p. 575-584 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density

    Eriksson, R., Broberg, B. V., Ishøy, P. L., Bak, N., Andersen, U. B., Jørgensen, N. R., Knop, F. K. & Ebdrup, B. H., 28 Jan 2019, In : Frontiers in Psychiatry. 9, 7 p., 781.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Bone mass development in childhood and its association with physical activity and vitamin D levels. The CHAMPS-Study DK

    Rønne, M. S., Heidemann, M., Lylloff, L., Schou, A. J., Tarp, J., Laursen, J. O., Jørgensen, N. R., Husby, S., Wedderkopp, N. & Mølgaard, C., Jan 2019, In : Calcified Tissue International. 104, 1, p. 1-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. E-pub ahead of print

    A review of sleep research in patients with spinal cord injury

    Hultén, V. D. T., Biering-Sørensen, F., Jørgensen, N. R. & Jennum, P. J., 2019, In : Journal of Spinal Cord Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    An explorative literature review of the multifactorial causes of osteoporosis in epilepsy

    Diemar, S. S., Sejling, A-S., Eiken, P., Andersen, N. B. & Jørgensen, N. R., 2019, In : Epilepsy and Behavior. 100, Pt A, p. 106511

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Biokemiske markører for knogleomsætning

    Jørgensen, N. R., Nissen, M. C. M. & Højsager, F. D., 2019, In : DSKB-Nyt. 2/2019, p. 14-17 4 p.

    Research output: Contribution to journalJournal articleCommunication

  33. Published

    Football for promotion of bone health across the lifespan

    Vlachopoulos, D., Williams, C. A., Helge, E. W., Per, A., Jørgensen, N. R. & Krustrup, P., 2019, Football as Medicine: Prescribing Football for Global Health Promotion. Krustrup, P. & Parnell, D. (eds.). Taylor & Francis Ltd, 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  34. Published
  35. Published

    Hyponatremia and metabolic bone disease in patients with epilepsy: A cross-sectional study

    Diemar, S. S., Sejling, A-S., Eiken, P., Suetta, C., Jørgensen, N. R. & Andersen, N. B., 2019, In : The Bone. 123, p. 67-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Standardisering af assays for 25-hydroxyvitamin D; hvor er vi nu?

    Jørgensen, N. R. & Bjerg, L. N., 2019, In : Klinisk Biokemi i Norden. 2/2019, p. 16-21 6 p.

    Research output: Contribution to journalJournal articleCommunication

  37. Published

    THE DIAGNOSTIC UTILITY OF THE RELATION BETWEEN MRI BONE MARROW EDEMA AND OTHER TYPES OF MRI LESIONS IN THE SACROILIAC JOINTS IN AXIAL SPONDYLOARTHRITIS

    Seven, S., Hededal, P., Østergaard, M., Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G. M., Lykkegaard, J. J., Hendricks, O., Jørgensen, N. R. & Pedersen, S. J., 2019, In : Annals of the Rheumatic Diseases. 78, Suppl. 2, p. 464-466 3 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  38. Published

    The Utility of Fat Lesions in Close Relation to Other Structural MRI Lesions in the Sacroiliac Joints for Diagnosing Patients with Axial Spondyloarthritis

    Seven, S., Østergaard, M., Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G. M., Lykkegaard, J. J., Hendricks, O., Jørgensen, N. R. & Pedersen, S. J., 2019, In : Arthritis & Rheumatology. 71, S10, 3 p., 1854.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. 2018
  40. Published

    Effects of high-dose, intravenous lipid emulsion on laboratory tests in humans: a randomized, placebo-controlled, double-blind, clinical crossover trial

    Petersen, K. M., Jørgensen, N. R., Bøgevig, S., Petersen, T. S., Jensen, T. B., Dalhoff, K. P. & Christensen, M. B., 27 Nov 2018, In : Clinical Chemistry and Laboratory Medicine. 56, 12, p. 2047-2057 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Comparison of bone turnover markers in peripheral blood and bone marrow aspirate

    Ornstrup, M. J., Kjær, T. N., Harsløf, T., Jørgensen, N. R., Pedersen, S. B. & Langdahl, B. L., Nov 2018, In : The Bone. 116, p. 315-320 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Melatonin and cortisol in individuals with spinal cord injury

    Thøfner Hultén, V. D., Biering-Sørensen, F., Jørgensen, N. R. & Jennum, P. J., Nov 2018, In : Sleep Medicine. 51, p. 92-98 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N., Lund, A., Heimbürger, S. M., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S348-S348 1 p., 717.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    Secondary Stroke Prophylaxis with Clopidogrel Produces Sufficient Antiplatelet Response

    Rath, C. L., Jørgensen, N. R. & Wienecke, T., Oct 2018, In : Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 27, 10, p. 2683-2690 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Osteogenic impact of football training in 55- to 70-year-old women and men with prediabetes

    Skoradal, M-B., Helge, E. W., Jørgensen, N. R., Mortensen, J., Weihe, P., Krustrup, P. & Mohr, M., Aug 2018, In : Scandinavian journal of medicine & science in sports. 28 Suppl 1, p. 52-60 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans

    Hansen, T. H., Madsen, M. T. B., Jørgensen, N. R., Cohen, A. S., Hansen, T., Vestergaard, H., Pedersen, O. & Allin, K. H., Jul 2018, In : European Journal of Clinical Nutrition. 72, p. 1046-1054 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effects of metformin, rosiglitazone and insulin on bone metabolism in patients with type 2 diabetes

    Stage, T. B., Christensen, M-M. H., Jørgensen, N. R., Beck-Nielsen, H., Brøsen, K., Gram, J. & Frost, M., Jul 2018, In : Bone. 112, p. 35-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    High-intensity intermittent "5-10-15" running reduces body fat, and increases lean body mass, bone mineral density, and performance in untrained subjects

    Ravnholt, T., Tybirk, J., Jørgensen, N. R. & Bangsbo, J., Jun 2018, In : European Journal of Applied Physiology. 118, 6, p. 1221-1230 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The purinergic P2X7 ion channel receptor - a 'repair' receptor in bone

    Jørgensen, N. R., Jun 2018, In : Current Opinion in Immunology. 52, p. 32-38 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum

    Crusell, M. K. W., Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, P., Vestergaard, H., Rørbye, C., Jørgensen, N. R., Christiansen, O. B., Heinsen, F-A., Franke, A., Hansen, T., Lauenborg, J. & Pedersen, O., 15 May 2018, In : Microbiome. 6, 1, p. 89

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Bone Turnover Markers in Patients with Non-Alcoholic Fatty Liver Disease and/or Type 2 Diabetes during Oral Glucose and Isoglycemic iv Glucose

    Maagensen, H., Junker, A. E., Jørgensen, N. R., Gluud, L. L., Knop, F. K. & Vilsbøll, T., 1 May 2018, In : The Journal of clinical endocrinology and metabolism. 103, 5, p. 2042-2049 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Effect of dapagliflozin on albuminuria and the renin-angiotensin system when added to renin-angiotensin blockade in patients with type 2 diabetes and nephropathy

    Eickhoff, M., Frimodt-Moller, M., Jorgensen, N. R., Rossing, P. & Persson, F., 1 May 2018, In : Nephrology Dialysis Transplantation. 33, 1, SP417 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  53. Published

    Erratum: Effect of GLP-1 receptor agonist treatment on body weight in obese antipsychotic-treated patients with schizophrenia: A randomized, placebo-controlled trial

    Ebdrup, B. H., Broberg, B. V., Ishøy, P. L., Bak, N., Andersen, U. B., Jørgensen, N. R., Holst, J. J., Knop, F. K. & Glenthøj, B. Y., May 2018, In : Diabetes, Obesity and Metabolism. 20, 5, p. 1327-8

    Research output: Contribution to journalJournal articleResearchpeer-review

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