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Rigshospitalet - a part of Copenhagen University Hospital
Niklas Rye Jørgensen

Niklas Rye Jørgensen

Professor, MD, DMSc, PhD

Valdemar Hansens Vej 13, indgang 3, VB, 2.sal

Building: Klinisk Biokemisk Afdeling, Rigshospitalet, Glostrup

2600 Glostrup

Denmark

  1. 2019
  2. Published

    Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

    Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, N. R., Vestergaard, H., Hansen, T., Hansen, T. H., Pedersen, O. & Nielsen, T., Jun 2019, In : Diabetologia. 62, 6, p. 1024-1035 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effects of Dapagliflozin on Volume Status When Added to Renin-Angiotensin System Inhibitors

    Eickhoff, M. K., Dekkers, C. C. J., Kramers, B. J., Laverman, G. D., Frimodt-Møller, M., Jørgensen, N. R., Faber, J., Danser, A. H. J., Gansevoort, R. T., Rossing, P., Persson, F. & Heerspink, H. J. L., 31 May 2019, In : Journal of Clinical Medicine. 8, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes

    Bergmann, N. C., Lund, A., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M. B., Vilsbøll, T. & Knop, F. K., 8 Mar 2019, In : The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Biochemical markers of inflammation are associated with increased mortality in hip fracture patients: the Bispebjerg Hip Fracture Biobank

    Norring-Agerskov, D., Bathum, L., Pedersen, O. B., Abrahamsen, B., Lauritzen, J. B., Jørgensen, N. R. & Jørgensen, H. L., 1 Feb 2019, In : Aging clinical and experimental research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density

    Eriksson, R., Broberg, B. V., Ishøy, P. L., Bak, N., Andersen, U. B., Jørgensen, N. R., Knop, F. K. & Ebdrup, B. H., 28 Jan 2019, In : Frontiers in Psychiatry. 9, p. 781

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. E-pub ahead of print

    A review of sleep research in patients with spinal cord injury

    Hultén, V. D. T., Biering-Sørensen, F., Jørgensen, N. R. & Jennum, P. J., 2019, In : Journal of Spinal Cord Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hyponatremia and metabolic bone disease in patients with epilepsy: A cross-sectional study

    Diemar, S. S., Sejling, A-S., Eiken, P., Suetta, C., Jørgensen, N. R. & Andersen, N. B., 2019, In : The Bone. 123, p. 67-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2018
  10. Published

    Effects of high-dose, intravenous lipid emulsion on laboratory tests in humans: a randomized, placebo-controlled, double-blind, clinical crossover trial

    Petersen, K. M., Jørgensen, N. R., Bøgevig, S., Petersen, T. S., Jensen, T. B., Dalhoff, K. P. & Christensen, M. B., 27 Nov 2018, In : Clinical Chemistry and Laboratory Medicine. 56, 12, p. 2047-2057 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Comparison of bone turnover markers in peripheral blood and bone marrow aspirate

    Ornstrup, M. J., Kjær, T. N., Harsløf, T., Jørgensen, N. R., Pedersen, S. B. & Langdahl, B. L., Nov 2018, In : The Bone. 116, p. 315-320 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Melatonin and cortisol in individuals with spinal cord injury

    Thøfner Hultén, V. D., Biering-Sørensen, F., Jørgensen, N. R. & Jennum, P. J., Nov 2018, In : Sleep Medicine. 51, p. 92-98 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N., Lund, A., Heimbürger, S. M., Gasbjerg, L. S., Jørgensen, N. R., Jessen, L., Hartmann, B., Holst, J. J., Christensen, M., Vilsbøll, T. & Knop, F. K., 1 Oct 2018, In : Diabetologia. 61, suppl 1, p. S348-S348 1 p., 717.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    Secondary Stroke Prophylaxis with Clopidogrel Produces Sufficient Antiplatelet Response

    Rath, C. L., Jørgensen, N. R. & Wienecke, T., Oct 2018, In : Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 27, 10, p. 2683-2690 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Osteogenic impact of football training in 55- to 70-year-old women and men with prediabetes

    Skoradal, M-B., Helge, E. W., Jørgensen, N. R., Mortensen, J., Weihe, P., Krustrup, P. & Mohr, M., Aug 2018, In : Scandinavian journal of medicine & science in sports. 28 Suppl 1, p. 52-60 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans

    Hansen, T. H., Madsen, M. T. B., Jørgensen, N. R., Cohen, A. S., Hansen, T., Vestergaard, H., Pedersen, O. & Allin, K. H., Jul 2018, In : European Journal of Clinical Nutrition. 72, p. 1046-1054 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effects of metformin, rosiglitazone and insulin on bone metabolism in patients with type 2 diabetes

    Stage, T. B., Christensen, M-M. H., Jørgensen, N. R., Beck-Nielsen, H., Brøsen, K., Gram, J. & Frost, M., Jul 2018, In : Bone. 112, p. 35-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    High-intensity intermittent "5-10-15" running reduces body fat, and increases lean body mass, bone mineral density, and performance in untrained subjects

    Ravnholt, T., Tybirk, J., Jørgensen, N. R. & Bangsbo, J., Jun 2018, In : European Journal of Applied Physiology. 118, 6, p. 1221-1230 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The purinergic P2X7 ion channel receptor - a 'repair' receptor in bone

    Jørgensen, N. R., Jun 2018, In : Current Opinion in Immunology. 52, p. 32-38 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum

    Crusell, M. K. W., Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, P., Vestergaard, H., Rørbye, C., Jørgensen, N. R., Christiansen, O. B., Heinsen, F-A., Franke, A., Hansen, T., Lauenborg, J. & Pedersen, O., 15 May 2018, In : Microbiome. 6, 1, p. 89

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bone Turnover Markers in Patients with Non-Alcoholic Fatty Liver Disease and/or Type 2 Diabetes during Oral Glucose and Isoglycemic iv Glucose

    Maagensen, H., Junker, A. E., Jørgensen, N. R., Gluud, L. L., Knop, F. K. & Vilsbøll, T., 1 May 2018, In : The Journal of clinical endocrinology and metabolism. 103, 5, p. 2042-2049 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effect of dapagliflozin on albuminuria and the renin-angiotensin system when added to renin-angiotensin blockade in patients with type 2 diabetes and nephropathy

    Eickhoff, M., Frimodt-Moller, M., Jorgensen, N. R., Rossing, P. & Persson, F., 1 May 2018, In : Nephrology Dialysis Transplantation. 33, 1, SP417 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Erratum: Effect of GLP-1 receptor agonist treatment on body weight in obese antipsychotic-treated patients with schizophrenia: A randomized, placebo-controlled trial

    Ebdrup, B. H., Broberg, B. V., Ishøy, P. L., Bak, N., Andersen, U. B., Jørgensen, N. R., Holst, J. J., Knop, F. K. & Glenthøj, B. Y., May 2018, In : Diabetes, Obesity and Metabolism. 20, 5, p. 1327-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

    Hagman, M., Helge, E. W., Hornstrup, T., Fristrup, B., Nielsen, J. J., Jørgensen, N. R., Andersen, J. L., Helge, J. W. & Krustrup, P., Apr 2018, In : Journal of Sport and Health Science. 7, 2, p. 159-168 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of OSteoporosis (PaVOS)- study protocol for a randomized controlled trial

    Jepsen, D. B., Ryg, J., Jørgensen, N. R., Hansen, S. & Masud, T., 16 Mar 2018, In : Trials. 19, 1, p. 186

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake

    Dreisig, K., Kristensen, N. P., Dommer, M. W., Jørgensen, N. R. & Kornum, B. R., 1 Mar 2018, In : Purinergic Signalling. 14, 1, p. 83-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Impact of Conventional Medical Therapy on Bone Mineral Density and Bone Turnover in Adult Patients with X-Linked Hypophosphatemia: A 6-Year Prospective Cohort Study

    Shanbhogue, V. V., Hansen, S., Jørgensen, N. R. & Beck-Nielsen, S. S., Mar 2018, In : Calcified Tissue International. 102, 3, p. 321-328 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis

    Wang, N., Agrawal, A., Jørgensen, N. R. & Gartland, A., 22 Feb 2018, In : Scientific Reports. 8, 1, p. 3507

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Bone mineral density and markers of bone turnover and inflammation in diabetes patients with or without a Charcot foot: An 8.5-year prospective case-control study

    Jansen, R. B., Christensen, T. M., Bülow, J., Rørdam, L., Holstein, P. E., Jørgensen, N. R. & Svendsen, O. L., 1 Feb 2018, In : Journal of Diabetes and its Complications. 32, 2, p. 164-170 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Identification of new biomarkers to promote personalised treatment of patients with inflammatory rheumatic disease: protocol for an open cohort study

    Biomarker Protocol Study Group, Kringelbach, T. M., Glintborg, B., Hogdall, E. V., Johansen, J. S., Hetland, M. L., Jørgensen, N. R., Sørensen, I. J., Dreyer, L., Østergaard, M., Bliddal, H., Jacobsen, S., Pedersen, S. J., Nielsen, C. T. & Jensen, D. V., 1 Feb 2018, In : BMJ Open. 8, 2, p. e019325

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. Published

    Bone Turnover Markers

    Cavalier, E., Eastell, R., Jørgensen, N. R., Makris, K., Vasikaran, S. & Morris, H. A., 2018, Encyclopedia of Endocrine Diseases. Martini, L. & Huhtaniemi, I. T. (eds.). 2 ed. Elsevier, Vol. 4. p. 116-127 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  33. Published

    Chronic hyponatremia - Why care? A case report

    Diemar, S. S., Sejling, A-S., Jørgensen, N. R. & Andersen, N. B., 2018, In : Seizure. 59, p. 123-125 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Effects of Dapagliflozin on Albuminuria, Renal Function, and Renin-Angiotensin-Aldosterone Hormones in Type 2 Diabetes

    Eickhoff, M. K., Frimodt-Møller, M., Jørgensen, N. R., Rossing, P. & Persson, F., 2018, In : Journal of the American Society of Nephrology. p. 770 1 p., SA-PO138.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published

    Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption independently of Insulin and Glycemia

    Christensen, M. B., Lund, A., Calanna, S., Jørgensen, N. R., Holst, J. J., Vilsbøll, T. & Knop, F. K., 2018, In : The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published
  37. Published

    Knogletæthedsmåling og biomarkører til monitorering af osteoporosebehandling

    Pedersen, S. B., Rand, M. S., Eiken, P. A. & Jørgensen, N. R., 2018, In : Ugeskrift for Laeger. 180, 21, p. 1987-1900

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Markers of Local Inflammation and Bone Resorption in the Acute Diabetic Charcot Foot

    Jansen, R. B., Christensen, T. M., Bülow, J., Rørdam, L., Jørgensen, N. R. & Svendsen, O. L., 2018, In : Journal of Diabetes Research. 2018, p. 5647981

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Diagnostic Utility of the Relation between MRI Bone Marrow Edema and Other Types of MRI Lesions in the Sacroiliac Joints in Axial Spondyloarthritis

    Seven, S., Hededal, P., Østergaard, M., Morsel-Carlsen, L., Sørensen, I. J., Bonde, B., Thamsborg, G. M., Hendricks, O., Jørgensen, N. R. & Pedersen, S. J., 2018, In : Arthritis & Rheumatology. 70, S9, 3 p., 864.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Whole-body Magnetic Resonance Imaging in Axial Spondyloarthritis: Reduction of Sacroiliac, Spinal, and Entheseal Inflammation in a Placebo-controlled Trial of Adalimumab

    Krabbe, S., Østergaard, M., Eshed, I., Sørensen, I. J., Jensen, B., Møller, J. M., Balding, L., Madsen, O. R., Asmussen, K., Eng, G., Jørgensen, N. R. & Pedersen, S. J., 2018, In : Journal of Rheumatology. 45, 5, p. 621-629 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2017
  42. Published

    Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis

    Jepsen, D. B., Thomsen, K., Hansen, S., Jørgensen, N. R., Masud, T. & Ryg, J., 29 Dec 2017, In : BMJ Paediatrics Open . 7, 12, p. e018342

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Bone turnover is altered in transgenic rats overexpressing the P2Y2 purinergic receptor

    Ellegaard, M., Agca, C., Petersen, S., Agrawal, A., Kruse, L. S., Wang, N., Gartland, A., Jensen, J-E. B., Jørgensen, N. R. & Agca, Y., 1 Dec 2017, In : Purinergic Signalling. 13, 4, p. 545-557

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Optimizing combination of vascular endothelial growth factor and mesenchymal stem cells on ectopic bone formation in SCID mice

    Dreyer, C. H., Kjaergaard, K., Ditzel, N., Jørgensen, N. R., Overgaard, S. & Ding, M., Dec 2017, In : Journal of Biomedical Materials Research - Part A. 105, 12, p. 3326-3332 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis

    Kvist, T. M., Syberg, S., Petersen, S., Ding, M., Jørgensen, N. R. & Schwarz, P., Dec 2017, In : Bone Reports. 7, p. 145-151 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Vitamin D Status and Muscle Function Among Adolescent and Young Swimmers

    Geiker, N. R. W., Hansen, M., Jakobsen, J., Kristensen, M., Larsen, R., Jørgensen, N. R., Hansen, B. S. & Bügel, S., Oct 2017, In : International Journal of Sport Nutrition and Exercise Metabolism. 27, 5, p. 399-407 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Bone turnover in women with prior gestational diabetes after 52 week's treatment with liraglutide

    Vedtofte, L., Nielsen-Hannerup, E., Foghsgaard, S., Mathiesen, E. R., Buhl, T., Christiansen, L. K., Svare, J., Clausen, T. D., Damm, P., Jørgensen, N. R., Knop, F. K. & Vilsbøll, T., 14 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  48. Published

    Role of the gut in glucose-induced suppression of bone resorption in patients with non-alcoholic fatty liver disease and/or type 2 diabetes

    Maagensen, HEG., Junker, A. E., Jørgensen, N. R., Gluud, L. L., Knop, F. K. & Vilsbøll, T., 13 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  49. Published

    The effect of liraglutide on bone turnover during exercise training in patients with type 2 diabetes

    Mensberg, P., Espersen, E., Sjøberg, K. A., Storgaard, H., Jørgensen, N. R., Nyby, S., Kiens, B., Richter, E., Knop, F. K. & Vilsbøll, T., 13 Sep 2017. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  50. Published

    Synchrotron radiation μCT and histology evaluation of bone-to-implant contact

    Neldam, C. A., Sporring, J., Rack, A., Lauridsen, T., Hauge, E-M., Jørgensen, H. L., Jørgensen, N. R., Feidenhansl, R. & Pinholt, E. M., Sep 2017, In : Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 45, 9, p. 1448-1457 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published

    Hyperkalemia is Associated with Increased 30-Day Mortality in Hip Fracture Patients

    Norring-Agerskov, D., Madsen, C. M., Abrahamsen, B., Riis, T., Pedersen, O. B., Jørgensen, N. R., Bathum, L., Lauritzen, J. B. & Jørgensen, H. L., 1 Jul 2017, In : Calcified Tissue International. 101, 1, p. 9-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Bone structural changes after gastric bypass surgery evaluated by HR-pQCT: a two-year longitudinal study

    Shanbhogue, V. V., Støving, R. K., Frederiksen, K. H., Hanson, S., Brixen, K., Gram, J., Jørgensen, N. R. & Hansen, S., Jun 2017, In : European Journal of Endocrinology. 176, 6, p. 685-693 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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