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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2021
  2. Published

    Cerebral lactate uptake during exercise is driven by the increased arterial lactate concentration

    Siebenmann, C., Sorensen, H., Bonne, T. C., Zaar, M., Aachmann-Andersen, N. J., Nordsborg, N. B., Nielsen, H. B., Secher, N. H., Lundby, C. & Rasmussen, P., 1 Dec 2021, In: Journal of Applied Physiology. 131, 6, p. 1824-1830 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. Published

    Association of the intraoperative peripheral perfusion index with postoperative morbidity and mortality in acute surgical patients: a retrospective observational multicentre cohort study

    Agerskov, M., Thusholdt, A. N. W., Holm-Sørensen, H., Wiberg, S., Meyhoff, C. S., Højlund, J., Secher, N. H. & Foss, N. B., Sep 2021, In: British Journal of Anaesthesia. 127, 3, p. 396-404 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Mesenteric traction syndrome in pigs: A single-blinded, randomized controlled trial

    Strandby, R. B., Osterkamp, J. T. F., Ambrus, R., Henriksen, A., Goetze, J. P., Secher, N. H., Achiam, M. P. & Svendsen, L-B., Jun 2021, In: Animal models and experimental medicine. 4, 2, p. 162-168 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    The role of lactate in sepsis and COVID-19: Perspective from contracting skeletal muscle metabolism

    Iepsen, U. W., Plovsing, R. R., Tjelle, K., Foss, N. B., Meyhoff, C. S., Ryrsø, C. K., Berg, R. M. G. & Secher, N. H., 31 May 2021, (E-pub ahead of print) In: Experimental Physiology. p. 1-9 9 p., EP089474.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Cardiorespiratory responses to high intensity skeletal muscle metaboreflex activation in chronic obstructive pulmonary disease

    Iepsen, U. W., Ryrsø, C. K., Rugbjerg, M., Secher, N. H., Barbosa, T. C., Lange, P., Thaning, P., Pedersen, B. K., Mortensen, S. P. & Fadel, P. J., Mar 2021, In: Clinical Physiology and Functional Imaging. 41, 2, p. 146-155 10 p., 12678.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of low vs. high haemoglobin transfusion trigger on cardiac output in patients undergoing elective vascular surgery: Post-hoc analysis of a randomized trial

    Møller, A., Wetterslev, J., Shahidi, S., Hellemann, D., Secher, N. H., Pedersen, O. B., Marcussen, K. V., Ramsing, B. G. U., Mortensen, A. & Nielsen, H. B., Mar 2021, In: Acta Anaesthesiologica Scandinavica. 65, 3, p. 302-312 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Cerebral vs. Cardiovascular Responses to Exercise in Type 2 Diabetic Patients

    Kim, Y-S., van der Ster, B. J. P., Brassard, P., Secher, N. H. & van Lieshout, J. J., 15 Jan 2021, In: Frontiers in Physiology. 11, p. 583155 583155.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    An Untargeted Urine Metabolomics Approach for Autologous Blood Transfusion Detection

    Bejder, J., Gürdeniz, G., Cuparencu, C., Hall, F., Gybel-Brask, M., Breenfeldt Andersen, A., Dragsted, L. O., Secher, N. H., Johansson, P. I. & Nordsborg, N. B., Jan 2021, In: Medicine and Science in Sports and Exercise. 53, 1, p. 236-243 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. 2020
  13. Published

    The central blood volume as measured by thoracic electrical impedance and plasma proANP is not compromised by donation of 900 mL of blood in men

    Gybel-Brask, M., Nordsborg, N. B., Goetze, J. P., Johansson, P. I., Secher, N. H. & Bejder, J., Dec 2020, In: Transfusion medicine (Oxford, England). 30, 6, p. 450-455 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The physiology of rowing with perspective on training and health

    Volianitis, S., Yoshiga, C. C. & Secher, N. H., Sep 2020, In: European Journal of Applied Physiology. 120, 9, p. 1943-1963 21 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    KATP channels modulate cerebral blood flow and oxygen delivery during isocapnic hypoxia in humans

    Rocha, M. P., Campos, M. O., Mattos, J. D., Mansur, D. E., Rocha, H. N. M., Secher, N. H., Nóbrega, A. C. L. & Fernandes, I. A., Aug 2020, In: The Journal of physiology. 598, 16, p. 3343-3356 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Hypertension impairs hypoxia-induced angiogenesis in men

    Garcia, V. P., Rocha, H. N. M., Rocha, M. P., Mattos, J. D., Campos, M. O., Mansur, D. E., Secher, N. H., Nóbrega, A. C. L., Fernandes, I. A. & Rocha, N. G., Jun 2020, In: Journal of Hypertension. 38, 6, p. 1131-1139 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published
  18. Published

    To survive a dive; cerebral oxygen delivery and our aquatic heritage

    Bain, A. R., Secher, N. H. & Bailey, D. M., Jun 2020, In: Experimental Physiology. 105, 6, p. 925-927 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Muscle-liver substrate fluxes in exercising humans and potential effects on hepatic metabolism

    Hu, C., Hoene, M., Plomgaard, P., Hansen, J. S., Zhao, X., Li, J., Wang, X., Clemmesen, J. O., Secher, N. H., Häring, H. U., Lehmann, R., Xu, G. & Weigert, C., 1 Apr 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, p. 1196-1209 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    CO2 supplementation dissociates cerebral oxygenation and middle cerebral artery blood velocity during maximal cycling

    Hansen, R. K., Nielsen, P. S., Schelske, M. W., Secher, N. H. & Volianitis, S., Mar 2020, In: Scandinavian journal of medicine & science in sports. 30, 3, p. 399-407 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Atrial fibrillation is associated with lean body mass in postmenopausal women

    Worm, M. S., Bager, C. L., Blair, J. P. M., Secher, N. H., Riis, B. J., Christiansen, C. & Nielsen, H. B., 17 Jan 2020, In: Scientific Reports. 10, 1, p. 573

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Differential vasomotor responses to isocapnic hyperoxia: cerebral versus peripheral circulation

    Mattos, J. D., Campos, M. O., Rocha, M. P., Mansur, D. E., Rocha, H. N. M., Garcia, V. P., Rocha, N. G., Alvares, T. S., Secher, N. H., Nóbrega, A. C. L. & Fernandes, I. A., 1 Jan 2020, In: American journal of physiology. Regulatory, integrative and comparative physiology. 318, 1, p. R182-R187

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Comments on the Review 'Does mean arterial blood pressure scale with body mass in mammals? Effect of measurement of blood pressure' Acta Physiol (Oxf)

    Sandal, P. H., Damgaard, M. & Secher, N. H., Jan 2020, In: Acta physiologica (Oxford, England). 228, 1, p. e13407 e13407.

    Research output: Contribution to journalEditorialResearchpeer-review

  24. 2019
  25. Published
  26. Published

    The age-related reduction in cerebral blood flow affects vertebral artery more than internal carotid artery blood flow

    Olesen, N. D., Nielsen, H. B., Olsen, N. V. & Secher, N. H., Jul 2019, In: Clinical Physiology and Functional Imaging. 39, 4, p. 255-260 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published
  28. Published

    Time Trial Performance Is Sensitive to Low-Volume Autologous Blood Transfusion

    Bejder, J., Andersen, A. B., Solheim, S. A., Gybel-Brask, M., Secher, N. H., Johansson, P. I. & Nordsborg, N. B., Apr 2019, In: Medicine and Science in Sports and Exercise. 51, 4, p. 692-700 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Cardiac output during exercise is related to plasma atrial natriuretic peptide but not to central venous pressure in humans

    Yoshiga, C., Dawson, E. A., Volianitis, S., Warberg, J. & Secher, N. H., Mar 2019, In: Experimental Physiology. 104, 3, p. 379-384 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Dynamic Cerebral Autoregulation Is Maintained during High-Intensity Interval Exercise

    Tsukamoto, H., Hashimoto, T., Olesen, N. D., Petersen, L. G., Sørensen, H., Nielsen, H. B., Secher, N. H. & Ogoh, S., Feb 2019, In: Medicine and Science in Sports and Exercise. 51, 2, p. 372-378 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Human brain blood flow and metabolism during isocapnic hyperoxia: the role of reactive oxygen species

    Mattos, J. D., Campos, M. O., Rocha, M. P., Mansur, D. E., Rocha, H. N. M., Garcia, V. P., Batista, G., Alvares, T. S., Oliveira, G. V., Souza, M. V., Videira, R. L. R., Rocha, N. G., Secher, N. H., Nóbrega, A. C. L. & Fernandes, I. A., Feb 2019, In: The Journal of physiology. 597, 3, p. 741-755 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published

    Hypoxia-induced vagal withdrawal is independent of the hypoxic ventilatory response in men

    Siebenmann, C., Ryrsø, C. K., Oberholzer, L., Fisher, J. P., Hilsted, L. M., Rasmussen, P., Secher, N. H. & Lundby, C., 1 Jan 2019, In: Journal of Applied Physiology. 126, 1, p. 124-131 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Fluid therapy for critical haemorrhage during elective noncardiac surgery

    Rasmussen, K. C., Secher, N. H. & Pedersen, T., Jan 2019, In: European Journal of Anaesthesiology. 36, 1, p. 77-78 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published

    Nasal insulin administration does not affect hepatic glucose production at systemic fasting insulin levels

    Plomgaard, P., Hansen, J. S., Ingerslev, B., Clemmesen, J. O., Secher, N. H., van Hall, G., Fritsche, A., Weigert, C., Lehmann, R., Häring, H-U. & Heni, M., 2019, In: Diabetes, Obesity and Metabolism. 21, 4, p. 993-1000 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Regulation of heart rate and blood pressure during exercise in humans

    Secher, N. H. & Fisher, J. P., 2019, Muscle and Exercise Physiology. p. 541-560 20 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  38. 2018
  39. Published
  40. Published

    Elevated Renal Oxygen Extraction During Open Abdominal Aortic Aneurysm Repair Is Related to Postoperative Renal Dysfunction

    Olesen, N. D., Jørgensen, T. B., Eiberg, J., Helgstrand, U. J. V., Sillesen, H. H., Cedergreen, P., Secher, N. H. & Nielsen, H. B., Dec 2018, In: Seminars in Cardiothoracic and Vascular Anesthesia. 22, 4, p. 369-375 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Elevated arterial lactate delays recovery of intracellular muscle pH after exercise

    Volianitis, S., Secher, N. H. & Quistorff, B., Nov 2018, In: European Journal of Applied Physiology. 118, 11, p. 2429-2434 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Phenylephrine increases near-infrared spectroscopy determined muscle oxygenation during head-up tilt in men

    Egesborg, A. H., Sørensen, H., Olesen, N. D. & Secher, N. H., 20 Oct 2018, In: Scandinavian Journal of Clinical and Laboratory Investigation. 78, 7-8, p. 601-605 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Absent increase in vertebral artery blood flow during l-arginine infusion in hypertensive men

    Vianna, L. C., Fernandes, I. A., Barbosa, T. C., Amaral, T. G., Rocha, N. G., Secher, N. H. & Nóbrega, A. C., 1 Oct 2018, In: American journal of physiology. Regulatory, integrative and comparative physiology. 315, 4, p. R820-R824

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Administration of platelets to ruptured abdominal aortic aneurysm patients before open surgery: a prospective, single-blinded, randomised study

    Lunen, T. B., Johansson, P. I., Jensen, L. P., Homburg, K. M., Roeder, O. C., Lonn, L., Secher, N. H., Helgstrand, U., Carstensen, M., Jensen, K. B., Lange, T., Sillesen, H., Swiatek, F. & Nielsen, H. B., Oct 2018, In: Transfusion medicine (Oxford, England). 28, 5, p. 386-391 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Pre-operative haemodynamic monitoring and resuscitation in hip fracture patients: Protocol for a prospective observational study

    Agerskov, M., Sørensen, H., Højlund, J., Secher, N. H. & Foss, N. B., Oct 2018, In: Acta Anaesthesiologica Scandinavica. 62, 9, p. 1314-1320

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Sodium nitroprusside dilates cerebral vessels and enhances internal carotid artery flow in young men

    Olesen, N. D., Fischer, M. & Secher, N. H., Sep 2018, In: The Journal of physiology. 596, 17, p. 3967-3976 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation

    Bailey, D. M., Rasmussen, P., Evans, K. A., Bohm, A. M., Zaar, M., Nielsen, H. B., Brassard, P., Nordsborg, N. B., Homann, P. H., Raven, P. B., McEneny, J., Young, I. S., McCord, J. M. & Secher, N. H., 20 Aug 2018, In: Free Radical Biology & Medicine. 124, p. 104-113 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Perioperativ væsketerapi har indflydelse på koagulation, blodtab og komplikationer

    Rasmussen, K. C., Pedersen, T. & Secher, N. H., 21 May 2018, In: Ugeskrift for Laeger. 180, 21, p. V06170498

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Reduced arterial vasodilatation in response to hypoxia impairs cerebral and peripheral oxygen delivery in hypertensive men

    Fernandes, I. A., Rocha, M. P., Campos, M. O., Mattos, J. D., Mansur, D. E., Rocha, H. N. M., Terra, P. A. C., Garcia, V. P., Rocha, N. G., Secher, N. H. & Nóbrega, A. C. L., 1 Apr 2018, In: The Journal of physiology. 596, 7, p. 1167-1179 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Matrix Metalloproteinase Mediated Type I Collagen Degradation is an Independent Predictor of Increased Risk of Acute Myocardial Infarction in Postmenopausal Women

    Bertelsen, D. M., Neergaard, J. S., Bager, C. L., Nielsen, S. H., Secher, N. H., Svendsen, J. H., Bihlet, A. R., Andersen, J. R., Karsdal, M. A., Christiansen, C. & Nielsen, H. B., 29 Mar 2018, In: Scientific Reports. 8, 1, p. 5371

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Muscle α-adrenergic responsiveness during exercise and ATP-induced vasodilation in chronic obstructive pulmonary disease patients

    Iepsen, U. W., Munch, G. W., Ryrsø, C. K., Secher, N. H., Lange, P., Thaning, P., Pedersen, B. K. & Mortensen, S. P., 1 Feb 2018, In: American Journal of Physiology: Heart and Circulatory Physiology. 314, 2, p. H180-H187

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published
  53. Published

    Maintained exercise-enhanced brain executive function related to cerebral lactate metabolism in men

    Hashimoto, T., Tsukamoto, H., Takenaka, S., Olesen, N. D., Petersen, L. G., Sørensen, H., Nielsen, H. B., Secher, N. H. & Ogoh, S., 2018, In: FASEB Journal. 32, 3, p. 1417-1427

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2017
  55. Published

    Tympanic membrane temperature decreases during head up tilt: relation to frontal lobe oxygenation and middle cerebral artery mean blood flow velocity

    Lorr, D., Lund, A., Fredrikson, M. & Secher, N. H., Dec 2017, In: Scandinavian Journal of Clinical and Laboratory Investigation. 77, 8, p. 587-591 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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