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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2020
  2. Published

    The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome

    Brieghel, C., da Cunha-Bang, C., Yde, C. W., Schmidt, A. Y., Kinalis, S., Nadeu, F., Andersen, M. A., Jacobsen, L. O., Andersen, M. K., Pedersen, L. B., Delgado, J., Baumann, T., Mattsson, M., Mansouri, L., Rosenquist, R., Campo, E., Nielsen, F. C. & Niemann, C. U., 15 Mar 2020, In : Clinical Cancer Research. 26, 6, p. 1507-1515 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2019
  4. Published
  5. 2018
  6. Published

    Lenalidomide plus bendamustine-rituximab does not overcome the adverse impact of TP53 mutations in mantle cell lymphoma

    Eskelund, C. W., Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Pedersen, L. B., Geisler, C. H., Jerkeman, M. & Grønbæk, K., Nov 2018, In : Haematologica. 3, 11, p. 541-543 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Depth and durability of response to ibrutinib in CLL: 5-year follow-up of a phase 2 study

    Ahn, I. E., Farooqui, M. Z. H., Tian, X., Valdez, J., Sun, C., Soto, S., Lotter, J., Housel, S., Stetler-Stevenson, M., Yuan, C. M., Maric, I., Calvo, K. R., Nierman, P., Hughes, T. E., Saba, N. S., Marti, G. E., Pittaluga, S., Herman, S. E. M., Niemann, C. U., Pedersen, L. B., Geisler, C. H., Childs, R., Aue, G. & Wiestner, A., 24 May 2018, In : Blood. 131, 21, p. 2357-2366 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial

    Jerkeman, M., Eskelund, C. W., Hutchings, M., Räty, R., Wader, K. F., Laurell, A., Toldbod, H., Pedersen, L. B., Niemann, C. U., Dahl, C., Kuitunen, H., Geisler, C. H., Grønbæk, K. & Kolstad, A., 1 Mar 2018, In : The Lancet. Haematology. 5, 3, p. 109-116

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    Patients with Chronic Lymphocytic Leukemia Belonging to the B-Cell Receptor Stereotypy Subset #2 Have Long Progression Free Survival after Chemo- or Chemoimmunotherapy in the HOVON68 Trial.

    Vojdeman, F. J., Pedersen, L. B., te Raa, G. D., Juvonen, V., Norden, Y., Tjønnfjord, G. E., Kimby, E., Itälä-Remes, M., Langerak, A. W., Evers, L. M., Zenz, T., van Oers, M., Geisler, C., Kater, A. P. & Niemann, C., 7 Dec 2017.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  11. Published

    Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes

    Xochelli, A., Baliakas, P., Kavakiotis, I., Agathangelidis, A., Sutton, L-A., Minga, E., Ntoufa, S., Tausch, E., Yan, X-J., Shanafelt, T., Plevova, K., Boudjogra, M., Rossi, D., Davis, Z., Navarro, A., Sandberg, Y., Vojdeman, F. J., Scarfò, L., Stavroyianni, N., Sudarikov, A., Veronese, S., Tzenou, T., Karan-Djurasevic, T., Catherwood, M., Kienle, D., Chatzouli, M., Facco, M., Bahlo, J., Pott, C., Pedersen, L. B., Mansouri, L., Smedby, K. E., Chu, C. C., Giudicelli, V., Lefranc, M-P., Panagiotidis, P., Juliusson, G., Anagnostopoulos, A., Vlahavas, I., Antic, D., Trentin, L., Montillo, M., Niemann, C., Döhner, H., Langerak, A. W., Pospisilova, S., Hallek, M., Campo, E., Chiorazzi, N., Maglaveras, N., Oscier, D. G., Gaidano, G., Jelinek, D. F., Stilgenbauer, S., Chouvarda, I., Darzentas, N., Belessi, C., Davi, F., Hadzidimitriou, A., Rosenquist, R., Ghia, P. & Stamatopoulos, K., Sep 2017, In : Clinical Cancer Research. 23, 17, p. 5292-5301

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Molecular Monitoring after Autologous Stem Cell Transplantation and Preemptive Rituximab Treatment of Molecular Relapse; Results from the Nordic Mantle Cell Lymphoma Studies (MCL2 and MCL3) with Median Follow-Up of 8.5 Years

    Kolstad, A., Pedersen, L. B., Eskelund, C. W., Husby, S., Grønbæk, K., Jerkeman, M., Laurell, A., Räty, R., Elonen, E., Andersen, N. S., Brown, P. D., Kimby, E., Bentzen, H., Sundström, C., Ehinger, M., Karjalainen-Lindsberg, M-L., Delabie, J., Ralfkiær, E., Fagerli, U-M., Nilsson-Ehle, H., Lauritzsen, G. F., Kuittinen, O., Niemann, C., Geisler, C. H. & Nordic Lymphoma Group, 2017, In : Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 23, 3, p. 428-435

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

    Eskelund, C. W., Dahl, C., Hansen, J. W., Westman, M., Kolstad, A., Pedersen, L. B., Montano-Almendras, C. P., Husby, S., Freiburghaus, C., Ek, S., Pedersen, A., Niemann, C., Räty, R., Brown, P., Geisler, C. H., Andersen, M. K., Guldberg, P., Jerkeman, M. & Grønbæk, K., 2017, In : Blood. 130, 17, p. 1903-1910

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2016
  15. Published

    15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

    Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J., Karjalainen-Lindsberg, M-L., Workman, C. T., Garde, C., Elonen, E., Brown, P., Grønbaek, K. & Geisler, C. H., Nov 2016, In : British Journal of Haematology. 175, 3, p. 410-418 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

    Sutton, L-A., Young, E., Baliakas, P., Hadzidimitriou, A., Moysiadis, T., Plevova, K., Rossi, D., Kminkova, J., Stalika, E., Pedersen, L. B., Malcikova, J., Agathangelidis, A., Davis, Z., Mansouri, L., Scarfò, L., Boudjoghra, M., Navarro, A., Muggen, A. F., Yan, X-J., Nguyen-Khac, F., Larrayoz, M., Panagiotidis, P., Chiorazzi, N., Niemann, C. U., Belessi, C., Campo, E., Strefford, J. C., Langerak, A. W., Oscier, D., Gaidano, G., Pospisilova, S., Davi, F., Ghia, P., Stamatopoulos, K., Rosenquist, R. & ERIC, the European Research Initiative on CLL, Aug 2016, In : Haematologica. 101, 8, p. 959-67 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Lenalidomide-bendamustine-rituximab in untreated mantle cell lymphoma > 65 years, the Nordic Lymphoma Group phase I+II trial NLG-MCL4

    Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Grønbæk, K., Sundberg, J., Pedersen, L. B., Ralfkiær, E., Karjalainen-Lindsberg, M-L., Sundström, C., Ehinger, M., Geisler, C. & Jerkeman, M., 27 Jun 2016, In : Blood. 128, 14, p. 1814-1820

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2015
  19. Published

    miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator

    Husby, S., Ralfkiaer, U., Garde, C., Zandi, R., Ek, S., Kolstad, A., Jerkeman, M., Laurell, A., Räty, R., Pedersen, L. B., Pedersen, A., Ehinger, M., Sundström, C., Karjalainen-Lindsberg, M-L., Delabie, J., Clasen-Linde, E., Brown, P., Cowland, J. B., Workman, C., Geisler, C. H. & Grønbæk, K., 23 Apr 2015, In : Blood. 125, 17, p. 2669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial

    Farooqui, M. Z. H., Valdez, J., Martyr, S., Aue, G., Saba, N., Niemann, C. U., Herman, S. E. M., Tian, X., Marti, G., Soto, S., Hughes, T. E., Jones, J., Lipsky, A., Pittaluga, S., Stetler-Stevenson, M., Yuan, C., Lee, Y. S., Pedersen, L. B., Geisler, C. H., Calvo, K. R., Arthur, D. C., Maric, I., Childs, R., Young, N. S. & Wiestner, A., Feb 2015, In : Lancet Oncology. 16, 2, p. 169-76 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations

    Baliakas, P., Agathangelidis, A., Hadzidimitriou, A., Sutton, L-A., Minga, E., Tsanousa, A., Scarfò, L., Davis, Z., Yan, X-J., Shanafelt, T., Plevova, K., Sandberg, Y., Vojdeman, F. J., Boudjogra, M., Tzenou, T., Chatzouli, M., Chu, C. C., Veronese, S., Gardiner, A., Mansouri, L., Smedby, K. E., Pedersen, L. B., Moreno, D., Van Lom, K., Giudicelli, V., Francova, H. S., Nguyen-Khac, F., Panagiotidis, P., Juliusson, G., Angelis, L., Anagnostopoulos, A., Lefranc, M-P., Facco, M., Trentin, L., Catherwood, M., Montillo, M., Geisler, C. H., Langerak, A. W., Pospisilova, S., Chiorazzi, N., Oscier, D., Jelinek, D. F., Darzentas, N., Belessi, C., Davi, F., Ghia, P., Rosenquist, R. & Stamatopoulos, K., 29 Jan 2015, In : Blood. 125, 5, p. 856-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2014
  23. Published

    Ibrutinib-induced lymphocytosis in patients with chronic lymphocytic leukemia: correlative analyses from a phase II study

    Herman, S. E. M., Niemann, C. U., Farooqui, M., Jones, J., Mustafa, R. Z., Lipsky, A., Saba, N., Martyr, S., Soto, S., Valdez, J. G., Gyamfi, J. A., Maric, I., Calvo, K. R., Pedersen, L. B., Geisler, C. H., Liu, D., Marti, G. E., Aue, G. & Wiestner, A., Nov 2014, In : Leukemia. 28, 11, p. 2188-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia

    Bergh, A-C., Evaldsson, C., Pedersen, L. B., Geisler, C., Stamatopoulos, K., Rosenquist, R. & Rosén, A., Nov 2014, In : Haematologica. 99, 11, p. 1722-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Continuous professional development for GPs: experience from Denmark

    Kjaer, N. K., Steenstrup, A. P., Pedersen, L. B. & Halling, A., Jul 2014, In : Postgraduate Medical Journal. 90, 1065, p. 383-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Nordic MCL3 study: 90Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma

    Kolstad, A., Laurell, A., Jerkeman, M., Grønbæk, K., Elonen, E., Räty, R., Pedersen, L. B., Loft, A., Bogsrud, T. V., Kimby, E., Hansen, P. B., Fagerli, U-M., Nilsson-Ehle, H., Lauritzsen, G. F., Lehmann, A. K., Sundstrom, C., Karjalainen-Lindsberg, M-L., Ralfkiaer, E., Ehinger, M., Delabie, J., Bentzen, H., Schildt, J., Kostova-Aherdan, K., Frederiksen, H., Brown, P. D. N., Geisler, C. H. & Nordic Lymphoma Group, 8 May 2014, In : Blood. 123, 19, p. 2953-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2013
  28. Published

    Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2

    Strefford, J. C., Sutton, L-A., Baliakas, P., Agathangelidis, A., Malčíková, J., Plevova, K., Scarfó, L., Davis, Z. J., Stalika, E., Cortese, D., Cahill, N., Pedersen, L. B., di Celle, P. F., Tzenou, T., Geisler, C., Panagiotidis, P., Langerak, A. W., Chiorazzi, N., Pospisilova, S., Oscier, D., Davi, F., Belessi, C., Mansouri, L., Ghia, P., Stamatopoulos, K. & Rosenquist, R., Nov 2013, In : Leukemia. 27, 11, p. 2196-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Molecular characterization of neoplastic and normal "sister" lymphoblastoid B-cell lines from chronic lymphocytic leukemia

    Lanemo Myhrinder, A., Hellqvist, E., Bergh, A-C., Jansson, M., Nilsson, K., Hultman, P., Jonasson, J., Buhl, A. M., Bredo Pedersen, L., Jurlander, J., Klein, E., Weit, N., Herling, M., Rosenquist, R. & Rosén, A., Aug 2013, In : Leukemia and Lymphoma. 54, 8, p. 1769-79 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2012
  31. Published

    Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity

    Kostareli, E., Gounari, M., Janus, A., Murray, F., Brochet, X., Giudicelli, V., Pospisilova, S., Oscier, D., Foroni, L., di Celle, P. F., Tichy, B., Pedersen, L. B., Jurlander, J., Ponzoni, M., Kouvatsi, A., Anagnostopoulos, A., Thompson, K., Darzentas, N., Lefranc, M-P., Belessi, C., Rosenquist, R., Davi, F., Ghia, P. & Stamatopoulos, K., 2012, In : Leukemia. 26, 5, p. 1127-31 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Nordic MCL2 trial update: six-year follow-up after intensive immunochemotherapy for untreated mantle cell lymphoma followed by BEAM or BEAC + autologous stem-cell support: still very long survival but late relapses do occur

    Geisler, C. H., Kolstad, A., Laurell, A., Jerkeman, M., Räty, R., Andersen, N. S., Pedersen, L. B., Eriksson, M., Nordström, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J., Karjalainen-Lindsberg, M-L., Brown, P., Elonen, E. & Nordic Lymphoma Group, 2012, In : British Journal of Haematology. 158, 3, p. 355-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

    Agathangelidis, A., Darzentas, N., Hadzidimitriou, A., Brochet, X., Murray, F., Yan, X-J., Davis, Z., van Gastel-Mol, E. J., Tresoldi, C., Chu, C. C., Cahill, N., Giudicelli, V., Tichy, B., Pedersen, L. B., Foroni, L., Bonello, L., Janus, A., Smedby, K., Anagnostopoulos, A., Merle-Beral, H., Laoutaris, N., Juliusson, G., di Celle, P. F., Pospisilova, S., Jurlander, J., Geisler, C., Tsaftaris, A., Lefranc, M-P., Langerak, A. W., Oscier, D. G., Chiorazzi, N., Belessi, C., Davi, F., Rosenquist, R., Ghia, P. & Stamatopoulos, K., 2012, In : Blood. 119, 19, p. 4467-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2011
  35. Published

    Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases

    Hadzidimitriou, A., Agathangelidis, A., Darzentas, N., Murray, F., Delfau-Larue, M-H., Pedersen, L. B., Lopez, A. N., Dagklis, A., Rombout, P., Beldjord, K., Kolstad, A., Dreyling, M. H., Anagnostopoulos, A., Tsaftaris, A., Mavragani-Tsipidou, P., Rosenwald, A., Ponzoni, M., Groenen, P., Ghia, P., Sander, B., Papadaki, T., Campo, E., Geisler, C., Rosenquist, R., Davi, F., Pott, C. & Stamatopoulos, K., 2011, In : Blood. 118, 11, p. 3088-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 30994454