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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2021
  2. Published

    Neurokinins and their receptors in the rat trigeminal system: Differential localization and release with implications for migraine pain

    Edvinsson, J. C., Reducha, P. V., Sheykhzade, M., Warfvinge, K., Haanes, K. A. & Edvinsson, L., 14 Dec 2021, In: Molecular Pain. 17, p. 17448069211059400 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine

    Christensen, S. L., Rasmussen, R. H., Ernstsen, C., La Cour, S., David, A., Chaker, J., Haanes, K. A., Christensen, S. T., Olesen, J. & Kristensen, D. M., Dec 2021, In: Cephalalgia : an international journal of headache. 41, 14, p. 1413-1426 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Ovariectomy reduces vasocontractile responses of rat middle cerebral arteries after focal cerebral ischemia

    Rehnström, M., Ahnstedt, H., Krause, D. N., Edvinsson, M. L., Haanes, K. A. & Edvinsson, L., 13 Oct 2021, (E-pub ahead of print) In: Journal of Cardiovascular Pharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP

    Krause, D. N., Warfvinge, K., Haanes, K. A. & Edvinsson, L., Oct 2021, In: Nature reviews. Neurology. 17, 10, p. 621-633 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. E-pub ahead of print
  7. Published
  8. Published
  9. Published

    Identifying New Antimigraine Targets: Lessons from Molecular Biology

    Edvinsson, L. & Haanes, K. A., Apr 2021, In: Trends in Pharmacological Sciences. 42, 4, p. 217-225 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. 2020
  11. Published

    Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects

    Warfvinge, K., Krause, D. N., Maddahi, A., Edvinsson, J. C. A., Edvinsson, L. & Haanes, K. A., Dec 2020, In: Journal of Headache and Pain. 21, 1, p. 131 131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published
  13. Published
  14. Published
  15. Lasmiditan inhibits calcitonin gene-related peptide release in the rodent trigeminovascular system

    Labastida-Ramírez, A., Rubio-Beltrán, E., Haanes, K. A., Chan, K. Y., Garrelds, I. M., Johnson, K. W., Danser, A. H. J., Villalón, C. M. & MaassenVanDenBrink, A., May 2020, In: Pain. 161, 5, p. 1092-1099 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Understanding side-effects of anti-CGRP and anti-CGRP receptor antibodies

    Haanes, K. A., Edvinsson, L. & Sams, A., 16 Mar 2020, In: The Journal of Headache and Pain Online. 21, 1, p. 26

    Research output: Contribution to journalLetterResearchpeer-review

  17. Published

    The role of purinergic P2Y12 and P2Y13 receptors in ADPβS-induced inhibition of the cardioaccelerator sympathetic drive in pithed rats

    Villanueva-Castillo, B., Rivera-Mancilla, E., Haanes, K. A., MaassenVanDenBrink, A. & Villalón, C. M., Mar 2020, In: Purinergic Signalling. 16, 1, p. 73-84 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Hyperpolarization through ATP-sensitive potassium channels; relevance to migraine pathology

    Haanes, K. A. & Edvinsson, L., 1 Feb 2020, In: Brain. 143, 2, p. e13

    Research output: Contribution to journalLetterResearchpeer-review

  19. Published

    Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction

    Bautista-Niño, P. K., Portilla-Fernandez, E., Rubio-Beltrán, E., van der Linden, J. J., de Vries, R., van Veghel, R., de Boer, M., Durik, M., Ridwan, Y., Brandt, R., Essers, J., Menzies, R. I., Thomas, R., de Bruin, A., Duncker, D. J., van Beusekom, H. M. M., Ghanbari, M., Hoeijmakers, J. H. J., Sedlacek, R., Touyz, R. M., Montezano, A. C., van der Pluijm, I., Danser, A. H. J., Haanes, K. A. & Roks, A. J. M., 2020, In: Clinical science (London, England : 1979). 134, 7, p. 727-746 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The fifth cranial nerve in headaches

    Edvinsson, J. C. A., Viganò, A., Alekseeva, A., Alieva, E., Arruda, R., De Luca, C., D'Ettore, N., Frattale, I., Kurnukhina, M., Macerola, N., Malenkova, E., Maiorova, M., Novikova, A., Řehulka, P., Rapaccini, V., Roshchina, O., Vanderschueren, G., Zvaune, L., Andreou, A. P., Haanes, K. A. & European Headache Federation School of Advanced Studies (EHF-SAS), 2020, In: The Journal of Headache and Pain Online. 21, 1, p. 65

    Research output: Contribution to journalReviewResearchpeer-review

  21. 2019
  22. Published
  23. Characterisation of vasodilatory responses in the presence of the CGRP receptor antibody erenumab in human isolated arteries

    Rubio-Beltrán, E., Labastida-Ramírez, A., Haanes, K. A., van den Bogaerdt, A., Bogers, A. J., Dirven, C., Danser, A. J., Xu, C., Snellman, J. & MaassenVanDenBrink, A., Dec 2019, In: Cephalalgia : an international journal of headache. 39, 14, p. 1735-1744 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system

    Edvinsson, J. C. A., Warfvinge, K., Krause, D. N., Blixt, F. W., Sheykhzade, M., Edvinsson, L. & Haanes, K. A., 12 Nov 2019, In: The Journal of Headache and Pain Online. 20, 1, p. 105 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Exploration of physiological and pathophysiological implications of miRNA-143 and miRNA-145 in cerebral arteries

    Christensen, S. T., Johansson, S. E., Warfvinge, K., Braun, T., Boettger, T., Edvinsson, L. & Haanes, K. A., Nov 2019, In: Journal of Cardiovascular Pharmacology. 74, 5, p. 409-419

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Exploration of purinergic receptors as potential anti-migraine targets using established pre-clinical migraine models

    Haanes, K. A., Labastida-Ramírez, A., Blixt, F. W., Rubio-Beltrán, E., Dirven, C. M., Danser, A. H., Edvinsson, L. & MaassenVanDenBrink, A., Oct 2019, In: Cephalalgia : an international journal of headache. 39, 11, p. 1421-1434 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Does inflammation have a role in migraine?

    Edvinsson, L., Haanes, K. A. & Warfvinge, K., 1 Aug 2019, In: Nature reviews. Neurology. 15, 8, p. 483-490 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Characterization of binding, functional activity, and contractile responses of the selective 5-HT1F receptor agonist lasmiditan

    Rubio-Beltrán, E., Labastida-Ramírez, A., Haanes, K. A., van den Bogaerdt, A., Bogers, A. J. J. C., Zanelli, E., Meeus, L., Danser, A. H. J., Gralinski, M. R., Senese, P. B., Johnson, K. W., Kovalchin, J., Villalón, C. M. & MaassenVanDenBrink, A., 1 Jan 2019, In: British Journal of Pharmacology. p. epub

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Synergistic effects of a cremophor EL drug delivery system and its U0126 cargo in an ex vivo model

    Christensen, S. T., Grell, A. S., Johansson, S. E., Andersson, C. M., Edvinsson, L. & Haanes, K. A., 1 Jan 2019, In: Drug Delivery . 26, 1, p. 680-688 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Effects of two isometheptene enantiomers in isolated human blood vessels and rat middle meningeal artery - potential antimigraine efficacy

    Labastida-Ramírez, A., Rubio-Beltrán, E., Haanes, K. A., de Vries, R., Dammers, R., Bogers, A. J. J. C., van den Bogaerdt, A., Daugherty, B. L., Danser, A. H. J., Villalón, C. M. & MaassenVanDenBrink, A., 2019, In: The Journal of Headache and Pain Online. 20, 1, p. 47 47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published
  34. Published

    MEK/ERK/1/2 sensitive vascular changes coincide with retinal functional deficit, following transient ophthalmic artery occlusion

    Blixt, F. W., Haanes, K. A., Ohlsson, L., Dreisig, K., Fedulov, V., Warfvinge, K. & Edvinsson, L., 2019, In: Experimental Eye Research. 179, p. 142-149 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Pathophysiological Mechanisms in Migraine and the Identification of New Therapeutic Targets

    Haanes, K. A. & Edvinsson, L., 2019, In: CNS Drugs. 33, 6, p. 525-537 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published
  37. 2018
  38. Published

    CGRP as the target of new migraine therapies - successful translation from bench to clinic

    Edvinsson, L., Haanes, K. A., Warfvinge, K. & Krause, D. N., 2018, In: Nature reviews. Neurology. 14, 6, p. 338-350 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Characterization of the trigeminovascular actions of several adenosine A2A receptor antagonists in an in vivo rat model of migraine

    Haanes, K. A., Labastida-Ramírez, A., Chan, K. Y., de Vries, R., Shook, B., Jackson, P., Zhang, J., Flores, C. M., Danser, A. H. J., Villalón, C. M. & MaassenVanDenBrink, A., 2018, In: The Journal of Headache and Pain Online. 19, 1, p. 41

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Increased endothelin-1-mediated vasoconstriction after organ culture in rat and pig ocular arteries can be suppressed with MEK/ERK1/2 inhibitors

    W Blixt, F., Kristian Haanes, A., Ohlsson, L., Christiansen, A. T., Warfvinge, K. & Edvinsson, L., 2018, In: Acta Ophthalmologica. 96, 5, p. e619-e625

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published
  42. Published
  43. 2017
  44. Published

    Changes in vasodilation following myocardial ischemia/reperfusion in rats

    Kristiansen, S. B., Sheykhzade, M., Edvinsson, L. & Haanes, K. A., 2017, In: Nitric Oxide: Biology and Chemistry. 70, p. 68-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published
  46. Published
  47. 2016
  48. Published
  49. Published

    Contractile Changes in the Vasculature After Subchronic Smoking: A Comparison Between Wild Type and Surfactant Protein D Knock-Out Mice

    Haanes, K. A., Kruse, L. S., Wulf-Johansson, H., Stottrup, C. C., Sorensen, G. L. & Edvinsson, L., May 2016, In: Nicotine & Tobacco Research. 18, 5, p. 642-6 5 p., ntv136.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Comment on "A second trigeminal CGRP receptor: function and expression of the AMY1 receptor"

    Haanes, K. A., Chan, K. Y. & MaassenVanDenBrink, A., Apr 2016, In: Annals of Clinical and Translational Neurology. 3, 4, p. 307-8 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  51. Published
  52. 2015
  53. Published
  54. Published

    Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells

    Kowal, J. M., Haanes, K. A., Christensen, N. M. & Novak, I., 2015, In: Cell Communication and Signaling. 13, p. 28

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Dural administration of inflammatory soup or Complete Freund's Adjuvant induces activation and inflammatory response in the rat trigeminal ganglion

    Lukács, M., Haanes, K. A., Majláth, Z., Tajti, J., Vécsei, L., Warfvinge, K. & Edvinsson, L., 2015, In: The Journal of Headache and Pain Online. 16, p. 564

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2014
  57. Published

    Characterization of the contractile P2Y14 receptor in mouse coronary and cerebral arteries

    Haanes, K. A. & Edvinsson, L., 25 Aug 2014, In: F E B S Letters. 588, 17, p. 2936-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Comparison of the vasodilator responses of isolated human and rat middle meningeal arteries to migraine related compounds

    Grände, G., Labruijere, S., Haanes, K. A., MaassenVanDenBrink, A. & Edvinsson, L., 2014, In: The Journal of Headache and Pain Online. 15, p. 22

    Research output: Contribution to journalJournal articleResearchpeer-review

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