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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2021
  2. E-pub ahead of print

    Maintenance therapy and risk of osteonecrosis in children and young adults with acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study

    Toksvang, L. N., Andrés-Jensen, L., Rank, C. U., Niinimäki, R., Nersting, J., Nielsen, S. N., Mogensen, S. S., Harila-Saari, A., Abrahamsson, J., Joelsson, J., Overgaard, U. M., Quist-Paulsen, P., Griškevičius, L., Jónsson, Ó. G., Vaitkevičienė, G., Frandsen, T. L., Toft, N., Grell, K. & Schmiegelow, K., Nov 2021, In: Cancer Chemotherapy and Pharmacology. 88, 5, p. 911-917 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Increments in DNA-thioguanine level during thiopurine enhanced maintenance therapy of acute lymphoblastic leukemia

    Larsen, R. H., Utke Rank, C., Grell, K., Nørgaard Møller, L., Malthe Overgaard, U., Kampmann, P., Nersting, J., Degn, M., Nygaard Nielsen, S., Holst, H., Klug Albertsen, B., Skov Wehner, P., Thude Callesen, M., Kanerva, J., Leth Frandsen, T., Als-Nielsen, B., Lyngsie Hjalgrim, L. & Schmiegelow, K., 27 May 2021, (E-pub ahead of print) In: Haematologica.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    TPMT polymorphisms and minimal residual disease after 6-mercaptopurine post-remission consolidation therapy of childhood acute lymphoblastic leukaemia

    Dreisig, K., Brünner, E. D., Marquart, H. V., Helt, L. R., Nersting, J., Frandsen, T. L., Jonsson, O. G., Taskinen, M., Vaitkeviciene, G., Lund, B., Abrahamsson, J., Lepik, K. & Schmiegelow, K., Apr 2021, In: Pediatric Hematology and Oncology. 38, 3, p. 227-238 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2020
  6. Published
  7. Published

    Gastrointestinal toxicity during induction treatment for childhood acute lymphoblastic leukemia: The impact of the gut microbiota

    De Pietri, S., Ingham, A. C., Frandsen, T. L., Rathe, M., Krych, L., Castro-Mejía, J. L., Nielsen, D. S., Nersting, J., Wehner, P. S., Schmiegelow, K., Hasle, H., Pamp, S. J. & Müller, K., 1 Oct 2020, In: International Journal of Cancer. 147, 7, p. 1953-1962 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia

    Tulstrup, M., Moriyama, T., Jiang, C., Grosjean, M., Nersting, J., Abrahamsson, J., Grell, K., Hjalgrim, L. L., Jónsson, Ó. G., Kanerva, J., Lund, B., Nielsen, S. N., Nielsen, R. L., Overgaard, U., Quist-Paulsen, P., Pruunsild, K., Vaitkeviciene, G., Wolthers, B. O., Zhang, H., Gupta, R., Yang, J. J. & Schmiegelow, K., 3 Sep 2020, In: Blood. 136, 10, p. 1161-1168 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Feasibility of monitoring peripheral blood to detect emerging clones in children with acute lymphoblastic leukemia†

    Saliba, J., Evensen, N. A., Meyer, J. A., Newman, D., Nersting, J., Narang, S., Ma, X., Schmiegelow, K. & Carroll, W. L., Jul 2020, In: Pediatric Blood & Cancer. 67, 7, p. e28306

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Sperm DNA Integrity is Unaffected by Thiopurine Treatment in Men With Inflammatory Bowel Disease

    Grosen, A., Nersting, J., Bungum, M., Christensen, L. A., Schmiegelow, K., Spanò, M., Julsgaard, M., Cordelli, E., Leter, G., Larsen, P. B., Hvas, C. L. & Kelsen, J., 1 Jan 2019, In: Journal of Crohn's & colitis. 13, 1, p. 3-11 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy

    Nersting, J., Nielsen, S. N., Grell, K., Paerregaard, M., Abrahamsson, J., Lund, B., Jonsson, O. G., Pruunsild, K., Vaitkeviciene, G., Kanerva, J., Schmiegelow, K. & Nordic Society of Paediatric Haematology and Oncology (NOPHO), 2019, In: Cancer Chemotherapy and Pharmacology. 83, 1, p. 53-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia

    Tulstrup, M., Grosjean, M., Nielsen, S. N., Grell, K., Wolthers, B. O., Wegener, P. S., Jonsson, O. G., Lund, B., Harila-Saari, A., Abrahamsson, J., Vaitkeviciene, G., Pruunsild, K., Toft, N., Holm, M., Hulegårdh, E., Liestøl, S., Griskevicius, L., Punab, M., Wang, J., Carroll, W. L., Zhang, Z., Dalgaard, M. D., Gupta, R., Nersting, J. & Schmiegelow, K., Dec 2018, In: Leukemia. 32, 12, p. 2527-2535 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Testing physical function in children undergoing intense cancer treatment-a RESPECT feasibility study

    Nielsen, M. K. F., Christensen, J. F., Frandsen, T. L., Thorsteinsson, T., Andersen, L. B., Christensen, K. B., Nersting, J., Faber, M., Schmiegelow, K. & Larsen, H. B., Aug 2018, In: Pediatric Blood & Cancer. 65, 8, p. e27100

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Interactions Between Thiopurine Metabolites, Adalimumab, and Antibodies Against Adalimumab in Previously Infliximab-Treated Patients with Inflammatory Bowel Disease

    Holmstrøm, R. B., Mogensen, D. V., Brynskov, J., Ainsworth, M. A., Nersting, J., Schmiegelow, K. & Steenholdt, C., Jun 2018, In: Digestive Diseases and Sciences. 63, 6, p. 1583-1591 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia

    Evensen, N. A., Madhusoodhan, P. P., Meyer, J., Saliba, J., Chowdhury, A., Araten, D. J., Nersting, J., Bhatla, T., Vincent, T. L., Teachey, D., Hunger, S. P., Yang, J., Schmiegelow, K. & Carroll, W. L., May 2018, In: Haematologica. 103, 5, p. 830-839 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Role of TPMT and ITPA variants in mercaptopurine disposition

    Gerbek, T., Ebbesen, M., Nersting, J., Frandsen, T. L., Appell, M. L. & Schmiegelow, K., Mar 2018, In: Cancer Chemotherapy and Pharmacology. 81, 3, p. 579-586 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A role for thiopurine metabolites in the synergism between thiopurines and infliximab in inflammatory bowel disease

    Mogensen, D. V., Brynskov, J., Ainsworth, M. A., Nersting, J., Schmiegelow, K. & Steenholdt, C., 2018, In: Journal of Crohn's & colitis. 12, 3, p. 298-305

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2017
  21. Published

    Hepatic sinusoidal obstruction syndrome during maintenance therapy of childhood acute lymphoblastic leukemia is associated with continuous asparaginase therapy and mercaptopurine metabolites

    Toksvang, L. N., De Pietri, S., Nielsen, S. N., Nersting, J., Albertsen, B. K., Wehner, P. S., Rosthøj, S., Lähteenmäki, P. M., Nilsson, D., Nystad, T. A., Grell, K., Frandsen, T. L. & Schmiegelow, K., Sep 2017, In: Pediatric Blood and Cancer. 64, 9, p. e26519

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial

    Nielsen, S. N., Grell, K., Nersting, J., Abrahamsson, J., Lund, B., Kanerva, J., Jónsson, Ó. G., Vaitkeviciene, G., Pruunsild, K., Hjalgrim, L. L. & Schmiegelow, K., Apr 2017, In: Lancet Oncology. 18, 4, p. 515-524 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Hepatotoxicity During Maintenance Therapy and Prognosis in Children With Acute Lymphoblastic Leukemia

    Ebbesen, M. S., Nygaard, U., Rosthøj, S., Sørensen, D., Nersting, J., Vettenranta, K., Wesenberg, F., Kristinsson, J., Harila-Saari, A. & Schmiegelow, K., Apr 2017, In: Journal of Pediatric Hematology / Oncology. 39, 3, p. 161-166 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2016
  25. Published

    Maintenance therapy of childhood acute lymphoblastic leukemia revisited-Should drug doses be adjusted by white blood cell, neutrophil, or lymphocyte counts?

    Schmiegelow, K., Nersting, J., Nielsen, S. N., Heyman, M., Wesenberg, F., Kristinsson, J., Vettenranta, K., Schrøeder, H., Weinshilboum, R., Jensen, K. L., Grell, K. & Rosthoej, S., Dec 2016, In: Pediatric Blood and Cancer. 63, 12, p. 2104-2111 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published
  27. Published

    Evaluation of a pediatric liquid formulation to improve 6-mercaptopurine therapy in children

    Tiphaine, A. D. B., Hjalgrim, L. L., Nersting, J., Breitkreutz, J., Nelken, B., Schrappe, M., Stanulla, M., Thomas, C., Bertrand, Y., Leverger, G., Baruchel, A., Schmiegelow, K. & Jacqz-Aigrain, E., 15 Feb 2016, In: European Journal of Pharmaceutical Sciences. 83, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

    Moriyama, T., Nishii, R., Perez-Andreu, V., Yang, W., Klussmann, F. A., Zhao, X., Lin, T-N., Hoshitsuki, K., Nersting, J., Kihira, K., Hofmann, U., Komada, Y., Kato, M., McCorkle, R., Li, L., Koh, K., Najera, C. R., Kham, S. K-Y., Isobe, T., Chen, Z., Chiew, E. K-H., Bhojwani, D., Jeffries, C., Lu, Y., Schwab, M., Inaba, H., Pui, C-H., Relling, M. V., Manabe, A., Hori, H., Schmiegelow, K., Yeoh, A. E. J., Evans, W. E. & Yang, J. J., 15 Feb 2016, In: Nature Genetics. 48, 4, p. 367-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2015
  30. Published
  31. Published

    Treatment-related Myelodysplastic Syndrome in a Child With Acute Myeloid Leukemia and TPMT Heterozygosity

    Stensman, L. M., Kjeldsen, E., Nersting, J., Schmiegelow, K. & Hasle, H., 2015, In: Journal of Pediatric Hematology/Oncology. 37, 4, p. e242-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2012
  33. Published
  34. 2011
  35. Published

    Cost-effective multiplexing before capture allows screening of 25 000 clinically relevant SNPs in childhood acute lymphoblastic leukemia

    Wesolowska, A., Dalgaard, M. D., Borst, L., Gautier, L., Bak, M., Weinhold, N., Nielsen, B. F., Helt, L. R., Audouze, K. M. L., Nersting, J., Tommerup, N., Brunak, S., Sicheritz-Ponten, T., Leffers, H., Schmiegelow, K. & Gupta, R., 1 Jun 2011, In: Leukemia. 25, 6, p. 1001-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2010
  37. Published

    DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma

    Hedeland, R. L., Hvidt, K., Nersting, J., Rosthøj, S., Dalhoff, K., Lausen, B. & Schmiegelow, K., 1 Aug 2010, In: Cancer Chemotherapy and Pharmacology. 66, 3, p. 485-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2006
  39. Published

    Spironolactone induces apoptosis in human mononuclear cells. Association between apoptosis and cytokine suppression

    Mikkelsen, M., Sønder, S. U., Nersting, J. & Bendtzen, K., 1 Apr 2006, In: Apoptosis. 11, 4, p. 573-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2003
  41. Published

    Maturation of human dendritic cells by monocyte-conditioned medium is dependent upon trace amounts of lipopolysaccharide inducing tumour necrosis factor alpha

    Nersting, J., Svenson, M., Andersen, V. & Bendtzen, K., 9 Oct 2003, In: Immunology Letters. 89, 1, p. 59-65 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2002
  43. Published

    Autoinflammatoriske sygdomme: et nyt begreb

    Nersting, J., Andersen, V. & Bendtzen, K., 9 Sep 2002, In: Ugeskrift for Laeger. 164, 37, p. 4269-71 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 31027873