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Rigshospitalet - a part of Copenhagen University Hospital
  1. 2020
  2. Published

    Highly sensitive quantification of optic neuritis intrathecal biomarker CXCL13

    Olesen, M. N., Nilsson, A. C., Pihl-Jensen, G., Soelberg, K. K., Olsen, D. A., Brandslund, I., Lillevang, S. T., Madsen, J. S., Frederiksen, J. L. & Asgari, N., Sep 2020, In : Multiple Sclerosis and Related Disorders. 44, p. 102281

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print
  4. 2019
  5. Published

    Affinity-Guided Conjugation to Antibodies for Use in Positron Emission Tomography

    Skovsgaard, M. B., Jeppesen, T. E., Mortensen, M. R., Nielsen, C. H., Madsen, J., Kjaer, A. & Gothelf, K. V., 20 Mar 2019, In : Bioconjugate Chemistry. 30, 3, p. 881-887 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Oxime Coupling of Active Site Inhibited Factor Seven with a Nonvolatile, Water-Soluble Fluorine-18 Labeled Aldehyde

    Jeppesen, T. E., Kristensen, L. K., Nielsen, C. H., Petersen, L. C., Kristensen, J. B., Behrens, C., Madsen, J. & Kjaer, A., 20 Mar 2019, In : Bioconjugate Chemistry. 30, 3, p. 775-784

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2018
  8. Published
  9. Published
  10. Published

    Site-SpecificCu Labeling of the Serine Protease, Active Site Inhibited Factor Seven Azide (FVIIai-N), Using Copper Free Click Chemistry

    Jeppesen, T. E., Kristensen, L. K., Nielsen, C. H., Petersen, L. C., Kristensen, J. B., Behrens, C., Madsen, J. & Kjaer, A., 17 Jan 2018, In : Bioconjugate Chemistry. 29, 1, p. 117-125 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2017
  12. Published

    Safety Aspects of Postanesthesia Care Unit Discharge without Motor Function Assessment after Spinal Anesthesia: A Randomized, Multicenter, Semiblinded, Noninferiority, Controlled Trial

    Aasvang, E. K., Jørgensen, C. C., Laursen, M. B., Madsen, J., Solgaard, S., Krøigaard, M., Kjærsgaard-Andersen, P., Mandøe, H., Hansen, T. B., Nielsen, J. U., Krarup, N. H., Skøtt, A. E. & Kehlet, H., Jun 2017, In : Anesthesiology. 126, 6, p. 1043-1052 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    (18)F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Madsen, J., Jensen, A. A., Gillings, N., Lehel, S., Herth, M. M., Knudsen, G. M. & Kristensen, J. L., 23 May 2017, In : Organic & biomolecular chemistry. 15, 20, p. 4351-4358 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published
  16. 2016
  17. Published
  18. Published

    Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?

    Rasmussen, H., Frokjaer, V. G., Hilker, R. W., Madsen, J., Anhøj, S., Oranje, B., Pinborg, L. H., Glenthøj, B. & Knudsen, G. M., Jul 2016, In : European Neuropsychopharmacology. 26, 7, p. 1248-1250 3 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    PET Imaging of Tissue Factor in Pancreatic Cancer Using 64Cu-Labeled Active Site-Inhibited Factor VII

    Nielsen, C. H., Jeppesen, T. E., Kristensen, L. K., Jensen, M. M., El Ali, H. H., Madsen, J., Wiinberg, B., Petersen, L. C. & Kjaer, A., Jul 2016, In : Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 57, 7, p. 1112-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Angiogenesis PET Tracer Uptake ((68)Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction in Minipigs

    Rasmussen, T., Follin, B., Kastrup, J., Brandt-Larsen, M., Madsen, J., Emil Christensen, T., Pharao Hammelev, K., Hasbak, P. & Kjær, A., 17 Jun 2016, In : Diagnostics. 6, 2, p. 26-29

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Quantitative PET Imaging of Tissue Factor Expression Using 18F-Labeled Active Site-Inhibited Factor VII

    Nielsen, C. H., Erlandsson, M., Jeppesen, T. E., Jensen, M. M., Kristensen, L. K., Madsen, J., Petersen, L. C. & Kjaer, A., Jan 2016, In : Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 57, 1, p. 89-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. Published

    Seasonal difference in brain serotonin transporter binding predicts symptom severity in patients with seasonal affective disorder

    Mc Mahon, B., Andersen, S. B., Madsen, M. K., Hjordt, L. V., Hageman, I., Dam, O. H., Svarer, C., da Cunha-Bang, S., Baaré, W. F. C., Madsen, J., Hasholt, L., Holst, K., Frokjaer, V. G. & Knudsen, G. M., 2016, In : Brain : a journal of neurology. 139, p. 1605-1614 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2015
  26. Published

    Synthesis and characterization of (18)F-labeled active site inhibited factor VII (ASIS)

    Erlandsson, M., Nielsen, C. H., Jeppesen, T. E., Kristensen, J., Petersen, L. C., Madsen, J. & Kjaer, A., 15 May 2015, In : Journal of Labelled Compounds and Radiopharmaceuticals. 58, 5, p. 196-201 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals

    Haahr, M. E., Hansen, D. L., Fisher, P. M., Svarer, C., Stenbæk, D. S., Madsen, K., Madsen, J., Holst, J. J., Baaré, W. F. C., Hojgaard, L., Almdal, T. & Knudsen, G. M., 8 Apr 2015, In : The Journal of Neuroscience : the official journal of the Society for Neuroscience. 35, 14, p. 5884-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. Published

    Pharmacokinetic Analysis of (64)Cu-ATSM Dynamic PET in Human Xenograft Tumors in Mice

    Li, F., Jørgensen, J. T., Madsen, J. & Kjaer, A., 2015, In : Diagnostics. 5, 2, p. 96-112 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2014
  31. Published

    uPAR Targeted Radionuclide Therapy with (177)Lu-DOTA-AE105 Inhibits Dissemination of Metastatic Prostate Cancer

    Persson, M., Juhl, K., Rasmussen, P., Brandt-Larsen, M., Madsen, J., Ploug, M. & Kjaer, A., 4 Aug 2014, In : Molecular Pharmaceutics. 11, 8, p. 2796-806 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published
  33. Published

    Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

    Herth, M. M., Leth-Petersen, S., Lehel, S., Hansen, M., Knudsen, G. M., Gillings, N., Madsen, J. & Kristensen, J. L., 30 Apr 2014, In : R S C Advances. 4, 41, p. 21347-21350 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published
  35. Published

    Dosimetry of 64Cu-DOTA-AE105, a PET tracer for uPAR imaging

    Persson, M., Binderup, T., Pfeifer, A., Madsen, J., Rasmussen, P., Kjaer, A. & Ali, H. H. E., Mar 2014, In : Nuclear Medicine and Biology. 41, 3, p. 290-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published
  37. Published
  38. 2013
  39. Published

    Preclinical safety assessment of the 5-HT2A receptor agonist PET radioligand [ 11C]Cimbi-36

    Ettrup, A., Holm, S., Hansen, M., Wasim, M., Santini, M. A., Palner, M., Madsen, J., Svarer, C., Kristensen, J. L. & Knudsen, G. M., Aug 2013, In : Molecular Imaging and Biology. 15, 4, p. 376-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    First (18)F-labeled ligand for PET imaging of uPAR: in vivo studies in human prostate cancer xenografts

    Persson, M., Liu, H., Madsen, J., Cheng, Z. & Kjaer, A., Jul 2013, In : Nuclear Medicine and Biology. 40, 5, p. 618-24 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    High tumor uptake of (64)Cu: implications for molecular imaging of tumor characteristics with copper-based PET tracers

    Jørgensen, J. T., Persson, M., Madsen, J. & Kjær, A., Apr 2013, In : Nuclear Medicine and Biology. 40, 3, p. 345-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Prefrontal serotonin transporter availability is positively associated with the cortisol awakening response

    Frøkjær, V., Erritzoe, D., Holst, K. K., Jensen, P. S., Rasmussen, P. M., Fisher, P., Baaré, W. F. C., Madsen, K. S., Madsen, J., Svarer, C. & Knudsen, G. M., Apr 2013, In : European Neuropsychopharmacology. 23, 4, p. 285-294

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    [18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice

    Jensen, M. M., Erichsen, K. D., Johnbeck, C. B., Björkling, F., Madsen, J., Jensen, P. B., Sehested, M., Højgaard, L. & Kjær, A., 2013, In : B M C Cancer. 13, p. 168

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    [18F]FLT and [18F]FDG PET for non-invasive treatment monitoring of the nicotinamide phosphoribosyltransferase inhibitor APO866 in human xenografts

    Jensen, M. M., Erichsen, K. D., Johnbeck, C. B., Björkling, F., Madsen, J., Bzorek, M., Jensen, P. B., Højgaard, L., Sehested, M. & Kjær, A., 2013, In : P L o S One. 8, 1, p. e53410

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Development of a (11)C-labeled tetrazine for rapid tetrazine-trans-cyclooctene ligation

    Herth, M. M., Andersen, V. L., Lehel, S., Madsen, J., Knudsen, G. M. & Kristensen, J. L., 2013, In : Chemical Communications. 49, 36, p. 3805-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Imaging of treatment response to the combination of carboplatin and paclitaxel in human ovarian cancer xenograft tumors in mice using FDG and FLT PET

    Munk Jensen, M., Erichsen, K. D., Björkling, F., Madsen, J., Jensen, P. B., Sehested, M., Højgaard, L. & Kjær, A., 2013, In : P L o S One. 8, 12, p. e85126

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Improved PET imaging of uPAR expression using new (64)Cu-labeled cross-bridged peptide ligands: comparative in vitro and in vivo studies

    Persson, M., Hosseini, M., Madsen, J., Jørgensen, T., Jensen, K. J., Kjaer, A. & Ploug, M., 2013, In : Theranostics. 3, 9, p. 618-32 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Radiolabelling and PET brain imaging of the α₁-adrenoceptor antagonist Lu AE43936

    Risgaard, R., Ettrup, A., Balle, T., Dyssegaard, A., Hansen, H. D., Lehel, S., Madsen, J., Pedersen, H., Püschl, A., Badolo, L., Bang-Andersen, B., Knudsen, G. M. & Kristensen, J. L., 2013, In : Nuclear Medicine and Biology. 40, 1, p. 135-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2012
  50. Published

    No change in [¹¹C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human

    Pinborg, L. H., Feng, L., Haahr, M. E., Gillings, N., Dyssegaard, A., Madsen, J., Svarer, C., Yndgaard, S., Kjaer, T. W., Parsey, R. V., Hansen, H. D., Ettrup, A., Paulson, O. B. & Knudsen, G. M., Oct 2012, In : Synapse (New York). 66, 10, p. 880-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    [18F]FLT PET for Non-Invasive Assessment of Tumor Sensitivity to Chemotherapy: Studies with Experimental Chemotherapy TP202377 in Human Cancer Xenografts in Mice

    Munk Jensen, M., Erichsen, K. D., Björkling, F., Madsen, J., Jensen, P. B., Sehested, M., Højgaard, L. & Kjær, A., 2012, In : P L o S One. 7, 11, p. e50618

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    (64)Cu-NODAGA-c(RGDyK) Is a Promising New Angiogenesis PET Tracer: Correlation between Tumor Uptake and Integrin α(V)β(3) Expression in Human Neuroendocrine Tumor Xenografts

    Oxboel, J., Schjoeth-Eskesen, C., El-Ali, H. H., Madsen, J. & Kjaer, A., 2012, In : International Journal of Molecular Imaging. 2012, p. 379807 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    (68)Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers

    Persson, M., Madsen, J., Ostergaard, S., Ploug, M. & Kjaer, A., 2012, In : Nuclear Medicine and Biology. 39, 4, p. 560-569

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published
  55. Published

    Quantitative PET Imaging of Human uPAR with 64CU-DOTA-AE105: Implications for visualizing Cancer Invasion

    Persson, M., Madsen, J., Østergaard, S., Jensen, M. M., Jørgensen, J. T., Juhl, K., Lehmann, C., Ploug, M. & Kjær, A., 2012, In : Journal of Nuclear Medicine. 53, p. 1-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published
  57. Published

    Use of cis-[18F]fluoro-proline for assessment of exercise-related collagen synthesis in musculoskeletal connective tissue

    Skovgaard, D. C., Kjaer, A., Heinemeier, K. M., Brandt-Larsen, M., Madsen, J. & Kjaer, M., 2012, In : P L o S One. 6, 2, p. 827-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2011
  59. Published

    Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects

    Madsen, K., Erritzøe, D., Mortensen, E. L., Gade, A., Madsen, J., Baaré, W. F. C., Knudsen, G. M. & Hasselbalch, S. G., 1 Feb 2011, In : Psychopharmacology. 213, 2-3, p. 573-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements

    Ettrup, A., Mikkelsen, J. D., Lehel, S., Madsen, J., Nielsen, E. Ø., Palner, M., Timmermann, D. B., Peters, D. & Knudsen, G. M., 2011, In : Journal of Nuclear Medicine. 52, 9, p. 1449-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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